Search Results (26)

Carbon fiber fabric reinforced composite laminates are widely used in the automotive and aerospace components, which are prone to suffering low velocity impacts. In this paper, helicoidal layups of fabrics inspired by the Bouligand type structure of the dactyl clubs of mantis shrimp are proposed to improve the impact resistance of carbon fiber fabric reinforced composite laminates. Low velocity impact tests and finite element simulation are carried out to investigate the effect of the rotation angle of helicoidal layups on the impact damage behaviors of composite laminates, including impact force response, energy absorption characteristics and damage mechanism. Results show that the simulation results of impact force–time response, absorbed energy–time response, and damage characteristics show good agreements with the experimental results. With the increase in impact energy, the maximum value of impact force, the absorbed energy and the energy absorption ratio for all specimens are all increased. Under all impact energies, the impact damage of specimens with helicoidal layups are lower than that of specimen QI1 (rotation angle of 0°), indicating that the helical layup of woven carbon fabric can sufficiently enhance the impact resistance of the composite material. Furthermore, the impact resistance of specimen HL2 (rotation angle of 12.8°) is the best, because it demonstrates the lowest impact damage and highest impact force under all energies. This work provides a bionic design guideline for the high impact performance of carbon fiber fabric reinforced composite laminate. Full article

This study aimed to identify the heat-resistant bioactive components of Enterococcus faecium HDRsEf1 (HDRsEf1) and investigate their beneficial mechanism. Heat-treated culture supernatants of HDRsEf1 significantly suppressed CXCL-1 expression in LPS-stimulated MODE-K cells (p < 0.001), indicating the presence of heat-resistant anti-inflammatory components. Crude protein (P-Ef1) and crude expolysaccharide (EPS-Ef1) were isolated from an HDRsEf1 culture supernatant using ammonium sulfate and ethanal precipitation. Critically, only crude EPS-Ef1 retained an anti-inflammatory effect after heat treatment, while crude P-Ef1 lost this activity. Further investigation revealed that crude EPS-Ef1 (25 μg/mL) promoted MODE-K cell proliferation via EdU assays (p < 0.001), potentially through an upregulation of PCNA mRNA expression (p < 0.001). Animal studies demonstrated that an oral administration of crude EPS-Ef1 (4 mg/kg bw, 14 days) significantly increased body weight gain and jejunal crypt depth (p < 0.05) while reducing intestinal CXCL-1 mRNA levels (p < 0.001). These in vivo findings are consistent with in vitro observations. A structural analysis using HPAEC and SEC-MALLS-RI characterized crude EPS-Ef1 as a heteropolysaccharide (Mw 80.3 kDa) with a near-spherical conformation (slope 0.13) composed of mannose, glucose, glucuronic acid, and galactose (5.4:4.4:1.2:1). In summary, this study identifies crude EPS-Ef1 as the heat-resistant postbiotic component. Crude EPS-Ef1 possesses the dual effects of suppressing intestinal inflammation and promoting intestinal epithelial cell proliferation, which provides a theoretical foundation for a crude EPS-Ef1-based postbiotic. Full article

Agricultural science and technology policies (ASTPs) have played a pivotal role in shaping agricultural innovation, sustainability, and cleaner production practices. Understanding how ASTPs diffuse is essential for optimizing policy design and advancing the green transition in agriculture. This study aims to investigate the diffusion of ASTPs in China, using a quantitative citation-based approach. The goal is to explore diffusion patterns, topic characteristics, and historical trajectories of ASTPs, thereby providing insights into policy transmission mechanisms that can inform future policy improvements. We analyze 3207 ASTP documents, focusing on policy citation links to examine the distribution, diffusion characteristics, and dynamics of policies. The analysis includes tracking topic evolution and identifying key policies while estimating the main diffusion paths. The results show that the top-down diffusion model is the dominant pattern of policy transmission, exhibiting the highest diffusion speed and both short- and long-term impacts. ASTPs have progressively expanded toward industrialization, informatization, and green development, with increased policy transmission efficiency. The diffusion process has formed three primary pathways: (i) enhancing agricultural innovation capacity, (ii) accelerating the transformation of technological achievements, and (iii) improving the agricultural science and technology innovation system. These pathways are critical to advancing sustainable and cleaner agricultural production. This study provides valuable insights into the diffusion of ASTPs and highlights key pathways for policy optimization. The findings suggest that enhancing policy frameworks and improving policy implementation efficiency will be crucial for facilitating the transition toward sustainable, low-carbon, and environmentally friendly agricultural practices. Future research should refine data sources and incorporate semantic analysis to capture more detailed policy transmission mechanisms. Full article

Innate immunity is critical for insects to adjust to complicated environments. Studying the insect immune system can aid in identifying novel insecticide targets and provide insights for developing novel pest control strategies. Insects recognize environmental pathogens through pattern recognition receptors, thus activating the innate immune system to eliminate pathogens. The innate immune system of insects primarily comprises cellular immunity and humoral immunity. Toll, immune deficiency, and Janus kinase/signal transducers and activators of transcription are the main signaling pathways regulating insect humoral immunity. Nevertheless, increasing research has revealed that immune signaling activated by microbes also performs non-immune roles while exerting immune roles, and insulin signaling performs a key role in mediating the connection between the immune system and non-immune physiological activities. Therefore, this paper first briefly reviews the main innate immune signaling and insulin signaling of insects, then summarizes the relationship between immune signaling activated by microbes and insect growth and development, reproduction, pesticide resistance, chemical communication, cell turnover, lifespan, sleep, energy generation pathways and their possible underlying mechanisms. Future research directions and methodologies are also proposed, aiming to provide insights into further study on the physiological mechanism linking microbes and insect hosts. Full article

Currently, the main limitations of Pd-coated Nb-TiFe dual-phase alloys include insufficient hydrogen permeability, susceptibility to hydrogen embrittlement (HE), and poor tolerance of H₂S poisoning. To address these issues, this study proposes a series of improvements. First, a novel Nb₁₅Ti₅₅Fe₃₀ alloy composed of a well-aligned Nb-TiFe eutectic was successfully prepared using directional solidification (DS) technology. After deposition with a Pd catalytic layer, this alloy exhibits high hydrogen permeability of 3.71 × 10⁻⁸ mol H₂ m⁻¹ s⁻¹ Pa^−1/2 at 673 K, which is 1.4 times greater than that of the as-cast counterpart. Second, to improve the H₂S corrosion resistance, a new Pd₈₈Au₁₂ catalytic layer was deposited on the surface using a multi-target magnetic control sputtering system. Upon testing in a 100 ppm H₂/H₂S mixture, this membrane exhibited better resistance to bulk sulfidation and a higher permeance recovery (ca. 58%) compared to pure Pd-coated membrane. This improvement is primarily due to the lower adsorption energies of the former with H₂S, which hinders the formation of bulk Pd₄S. Finally, the composition region of the Pd-Au catalytic membrane with high comprehensive performance was determined for the first time, revealing that optimal performance occurs at around 12–18 at.% Au. This finding explains how this composition maintains a balance between high H₂ permeability and excellent sulfur resistance. The significance of this study lies in its practical solutions for simultaneously improving hydrogen permeability and resistance to H₂S poisoning in Nb-based composite membranes. Full article

Polysaccharides (AOPs) were extracted from Alpiniae oxyphyllae fructus using three distinct methods: hot water (AOP-HW), hydrochloric acid (AOP-AC), and NaOH/NaBH4 (AOP-AL). This study systematically investigated and compared the physicochemical properties, structural characteristics, antioxidant activities, and α-amylase inhibitory activities of the extracted polysaccharides. Among the three AOPs, AOP-AC exhibited the highest yield (13.76%) and neutral sugar content (80.57%), but had the lowest molecular weight (121.28 kDa). Conversely, AOP-HW had the lowest yield (4.54%) but the highest molecular weight (385.42 kDa). AOP-AL was predominantly composed of arabinose (28.42 mol%), galacturonic acid (17.61 mol%), and galactose (17.09 mol%), while glucose was the major sugar in both AOP-HW (52.31 mol%) and AOP-AC (94.77 mol%). Functionally, AOP-AL demonstrated superior scavenging activities against DPPH, hydroxyl, and ABTS radicals, whereas AOP-AC exhibited the strongest inhibitory effect on α-amylase. These findings indicate that the extraction solvent significantly influences the physicochemical and biological properties of AOPs, thus guiding the selection of appropriate extraction methods for specific applications. The results of this study have broad implications for industries seeking natural polysaccharides with antioxidant and enzymatic inhibitory properties. Full article

Studying the effects of maize and soybean intercropping for improving the maize yield and sustaining stability of the maize yield under different phosphate (P) application rates in red soil is crucial for promoting maize productivity, improving soil fertility and optimizing P nutrient management in southwest China. The objective of this study was to evaluate the dynamic changes in maize yield, yield stability and soil fertility under monoculture and intercropping maize with different P application rates. A six-year field experiment was conducted from 2017 to 2022 to investigate the effects of maize intercropping with soybean on the yield stability and sustainability of maize according to the changes in the maize yield, biomass, partial land equivalent ratio of yield (pLERY), actual yield loss index (AYL), contribution rate of soil capacity and fertilizer (SCR, SFCR) over time, as well as the differences in the coefficient of variation (CV) and sustainable yield index (SYI) at four P application rates (0 kg P₂O₅ ha⁻¹, P0; 60 kg P₂O₅ ha⁻¹, P1; 90 kg P₂O₅ ha⁻¹, P2; and 120 kg P₂O₅ ha⁻¹, P3) based on the two-factor randomized block design. The linear-platform model was utilized to simulate the relationship between the grain yield, the SYI and the amount of P fertilizer under different P application rates. The maize yield in intercropping was significantly superior to the maize yield in monoculture throughout the entire six-year experiment. For all planting years, the yield and biomass of the intercropping were higher than those of the matched monoculture average by 56.0% and 56.1%, respectively. Intercropping had an advantage of pLERY and AYL for maize. Otherwise, intercropping reduced the CV by 30.8% and 39.1% and increased the SYI by 39.4% and 23.0% in P0 and P3 compared with the matched monoculture, respectively. For all planting years, the average SFCR in intercropping treatment was higher than that in monoculture treatment. The linear-plateau model fitted showed that intercropping increased the yield and SYI by 19.8% and 40.7% on the platform and reduced the P application rate by 37.8% and 11.9% at the inflection point, respectively. These results demonstrate that maize and soybean intercropping could achieve a higher yield, a higher yield stability and an SYI with a lower P input than monoculture. Maize and soybean intercropping could be a sustainable practice for promoting the maize productivity and the yield sustainability in the red soil of southwest China. Full article

Background: Long COVID, characterized by a persistent symptom spectrum following SARS-CoV-2 infection, poses significant health, social, and economic challenges. This review aims to consolidate knowledge on its epidemiology, clinical features, and underlying mechanisms to guide global responses; Methods: We conducted a literature review, analyzing peer-reviewed articles and reports to gather comprehensive data on long COVID’s epidemiology, symptomatology, and management approaches; Results: Our analysis revealed a wide array of long COVID symptoms and risk factors, with notable demographic variability. The current understanding of its pathophysiology suggests a multifactorial origin yet remains partially understood. Emerging diagnostic criteria and potential therapeutic strategies were identified, highlighting advancements in long COVID management; Conclusions: This review highlights the multifaceted nature of long COVID, revealing a broad spectrum of symptoms, diverse risk factors, and the complex interplay of physiological mechanisms underpinning the condition. Long COVID symptoms and disorders will continue to weigh on healthcare systems in years to come. Addressing long COVID requires a holistic management strategy that integrates clinical care, social support, and policy initiatives. The findings underscore the need for increased international cooperation in research and health planning to address the complex challenges of long COVID. There is a call for continued refinement of diagnostic and treatment modalities, emphasizing a multidisciplinary approach to manage the ongoing and evolving impacts of the condition. Full article

This study investigates the corrosion behavior of Ni-Cr binary alloys, including Ni-10Cr, Ni-15Cr, Ni-20Cr, Ni-25Cr, and Ni-30Cr, in a NaCl-KCl-MgCl₂ molten salt mixture through gravimetric analysis. Corrosion tests were conducted at 700 °C, with the maximum immersion time reaching up to 100 h. The corrosion rate was determined by measuring the mass loss of the specimens at various time intervals. Verifying corrosion rates by combining mass loss results with the determination of element dissolution in molten salts using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). Detailed examinations of the corrosion products and morphology were conducted using X-ray diffraction (XRD) and scanning electron microscopy (SEM). Micro-area elemental analysis on the corroded surfaces was performed using an energy dispersive spectrometer (EDS), and the elemental distribution across the corrosion cross-sections was mapped. The results indicate that alloys with lower Cr content exhibit superior corrosion resistance in the NaCl-KCl-MgCl₂ molten salt under an argon atmosphere compared to those with higher Cr content; no corrosion products were retained on the surfaces of the lower Cr alloys (Ni-10Cr, Ni-15Cr). For the higher Cr alloys (Ni-20Cr, Ni-25Cr, Ni-30Cr), after 20 h of corrosion, a protective layer was observed in certain areas. The formation of a stable Cr₂O₃ layer in the initial stages of corrosion for high-Cr content alloys, which reacts with MgO in the molten salt to form a stable MgCr₂O₄ spinel structure, provides additional protection for the alloys. However, over time, even under argon protection, the MgCr₂O₄ protective layer gradually degrades due to chloride ion infiltration and chemical reactions at high temperatures. Further analysis revealed that chloride ions play a pivotal role in the corrosion process, not only facilitating the destruction of the Cr₂O₃ layer on the alloy surfaces but also possibly accelerating the corrosion of the metallic matrix through electrochemical reactions. In conclusion, the corrosion behavior of Ni-Cr alloys in the NaCl-KCl-MgCl₂ molten salt environment is influenced by a combination of factors, including Cr content, chloride ion activity, and the formation and degradation of protective layers. This study not only provides new insights into the corrosion resistance of Ni-Cr alloys in high-temperature molten salt environments but also offers significant theoretical support for the design and optimization of corrosion-resistant alloy materials. Full article

In this study, a novel fabrication method was used to synthesize phenolic resin/phosphate hybrid coatings using aluminum dihydrogen phosphate (Al(H₂PO₄)₃, hereafter denoted as Al), SC101 silica sol (Si) as the primary film-forming agent, and phenolic resin (PF) as the organic matrix. This approach culminated in the formation of Al+Si+PF organo–inorganic hybrid coatings. Fourier-transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) results confirmed the successful integration of hybrid structures within these coatings. The crystalline structure of the coatings post-cured at various temperatures was elucidated using X-ray diffraction (XRD). Additionally, the surface and cross-sectional morphologies were meticulously analyzed using scanning electron microscopy (SEM), offering insights into the microstructural properties of the coatings. The coatings’ porosities under diverse thermal and temporal regimes were quantitatively evaluated using advanced image processing techniques, revealing a significant reduction in porosity to a minimum of 5.88% following a thermal oxidation process at 600 °C for 10 h. The antioxidant efficacy of the phosphate coatings was rigorously assessed through cyclic oxidation tests, which revealed their outstanding performance. Specifically, at 300 °C across 300 h of cyclic oxidation, the weight losses recorded for phosphate varnish and the phenolic resin-infused phosphate coatings were 0.15 mg·cm⁻² and 0.09 mg·cm⁻², respectively. Furthermore, at 600 °C and over an identical period, the weight reduction was noted as 0.21 mg·cm⁻² for phosphate varnish and 0.085 mg·cm⁻² for the hybrid coatings, thereby substantiating the superior antioxidation capabilities of the phenolic resin hybrid coatings in comparison to the pure phosphate varnish. Full article

Antimicrobial peptides (AMPs), as immune effectors synthesized by a variety of organisms, not only constitute a robust defense mechanism against a broad spectrum of pathogens in the host but also show promising applications as effective antimicrobial agents. Notably, insects are significant reservoirs of natural AMPs. However, the complex array of variations in types, quantities, antimicrobial activities, and production pathways of AMPs, as well as evolution of AMPs across insect species, presents a significant challenge for immunity system understanding and AMP applications. This review covers insect AMP discoveries, classification, common properties, and mechanisms of action. Additionally, the types, quantities, and activities of immune-related AMPs in each model insect are also summarized. We conducted the first comprehensive investigation into the diversity, distribution, and evolution of 20 types of AMPs in model insects, employing phylogenetic analysis to describe their evolutionary relationships and shed light on conserved and distinctive AMP families. Furthermore, we summarize the regulatory pathways of AMP production through classical signaling pathways and additional pathways associated with Nitric Oxide, insulin-like signaling, and hormones. This review advances our understanding of AMPs as guardians in insect immunity systems and unlocks a gateway to insect AMP resources, facilitating the use of AMPs to address food safety concerns. Full article

Quercetin (QCT) is a promising dose-dependent nutraceutical that usually suffers from poor water solubility and low bioavailability issues. In this work, a novel QCT-loaded nanoscale delivery system was constructed based on the oxidative self-polymerization of melanin (Q@MNPs). The FT-IR, XRD, and Zeta potential analyses confirmed that QCT was successfully absorbed on the melanin nanoparticles (MNPs) via Π−Π and hydrogen bonding interactions. The encapsulation efficiency and particle size of Q@MNPs were 43.78% and 26.68 nm, respectively. Q@MNPs improved the thermal stability of QCT and the antioxidant properties in comparison to MNPs. Meanwhile, Q@MNPs presented fantastic photothermal conversion capacity and stability triggered by the NIR laser, which significantly enhanced the antibacterial capability with a sterilization rate of more than 98% against E. coli and S. aureus. More importantly, Q@MNPs exhibited NIR/pH dual-responsive drug release behavior and good biocompatibility (at concentrations of < 100 μg/mL). Thus, Q@MNPs show promising prospects for flavonoid delivery. Full article

The attitude measurement system based on geomagnetic information offers advantages such as small space requirements, fast response times, excellent resistance to high-overload conditions, and cost-effectiveness. However, during the flight process of a high-mobility guided spinning projectile, calculating attitude based on geomagnetic information often leads to non-unique solutions. To address this challenge, this paper proposes the Adaptive Extended Kalman Filter (AEKF) attitude estimation algorithm, based on geomagnetic vector information. Based on the analysis of the short-term attitude motion characteristics of the projectile, the Kalman state system equation and the nonlinear observation equation are established, along with real-time correction of the yaw angle and adaptive updates of parameters. The effectiveness of the algorithm is verified by simulations and experiments, demonstrating its ability to eliminate the dual solution problem inherent in traditional Single-Epoch algorithms. It notably improves the accuracy of pitch and roll angle estimation while providing precise estimates of attitude angular rates. Furthermore, the algorithm effectively mitigates the impact of magnetic disturbances on attitude determination. The proposed method has many potential applications in attitude measurement and navigation using geomagnetic data. Full article

Antibiotic resistance is a significant and growing threat to global public health. However, antimicrobial peptides (AMPs) have shown promise as they exhibit a broad spectrum of antibacterial activities with low potential for resistance development. Insects, which inhabit a wide range of environments and are incredibly diverse, remain largely unexplored as a source of novel AMPs. To address this, we conducted a screening of the representative transcriptomes from the 1000 Insect Transcriptome Evolution (1KITE) dataset, focusing on the homologous reference genes of Cecropins, the first identified AMPs in insects known for its high efficiency. Our analysis identified 108 Cecropin genes from 105 insect transcriptomes, covering all major hexapod lineages. We validated the gene sequences and synthesized mature peptides for three identified Cecropin genes. Through minimal inhibition concentration and agar diffusion assays, we confirmed that these peptides exhibited antimicrobial activities against Gram-negative bacteria. Similar to the known Cecropin, the three Cecropins adopted an alpha-helical conformation in membrane-like environments, efficiently disrupting bacterial membranes through permeabilization. Importantly, none of the three Cecropins demonstrated cytotoxicity in erythrocyte hemolysis tests, suggesting their safety in real-world applications. Overall, this newly developed methodology provides a high-throughput bioinformatic pipeline for the discovery of AMP, taking advantage of the expanding genomic resources available for diverse organisms. Full article

Nutrients can greatly affect host immune defenses against infection. Possessing a simple immune system, insects have been widely used as models to address the relationships between nutrition and immunity. The effects of high versus low protein-to-carbohydrate ratio (P:C) diets on insect immune responses vary in different studies. To reveal the dietary manipulation of immune responses in the polyphagous agricultural pest oriental armyworm, we examined immune gene expression, phenoloxidase (PO) activity, and phagocytosis to investigate the immune traits of bacteria-challenged oriental armyworms, which were fed different P:C ratio diets. We found the oriental armyworms that were fed a 35:7 (P:C) diet showed higher phenoloxidase (PO) activity and stronger melanization, and those reared on a 28:14 (P:C) diet showed higher antimicrobial activity. However, different P:C diets had no apparent effect on the hemocyte number and phagocytosis. These results overall indicate that high P:C diets differently optimize humoral immune defense responses in oriental armyworms, i.e., PO-mediated melanization and antimicrobial peptide synthesis in response to bacteria challenge. Full article