Chronic Viral Hepatitis in the Italian Prison Setting: Prevalence, Outcomes, Literature Needs and Perspectives
Abstract
:1. Introduction
2. Methods
3. Results
3.1. Reported Prevalence of Blood-Borne Viruses in Correctional Facilities: Older Concepts
3.2. New Evidence in Viral Hepatitis Epidemiology
3.3. Special Populations: Incarcerated People Living with HIV/HCV Co-Infection
3.4. Patients’ Clinical Features
3.5. HCV Treatment and Outcomes
3.6. Future Perspectives: HCV Fast-Track Test-and-Treat Approach
3.7. Female Incarcerated Population: The Harder-to-Reach-Population
4. Discussion
5. Conclusions
6. Limitations of the Study
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Literature Data | Year | Included Subjects | Median Age | Male Sex % | HCV-Ab Prevalence % | HBsAg/ HBcAb Prevalence | PWIDs | HIV-Ab +n (%) |
---|---|---|---|---|---|---|---|---|
Babudieri et al. [16] | 2005 | 973 | 36 | 87% | 38% | 6.7%/59.4% | 30.4% | 73 (7.5) |
Pontali et al. [25] | 2008 | 173 | NA | 100% | 90.8% | 6.7%/77.4% | 91.9% | 173 |
Voller et al. [17] | 2011 | 15,751 | 39.6 | 94.2% | 9.0% | 2.2%/NA | NA | NA |
Sagnelli et al. [18] | 2012 | 3468 | NA | NA | 22.8% | 4.4%/NA | NA | 89 (3.8) |
Brandolini et al. | 2013 | 695 | 43 | 97.8% | 22.4% | 6.2%/NA | NA | 67 (9.6) |
Foschi et al. [20] | 2016 | 468 | NA | NA | 9.8% | 6.6%/NA | NA | 15 (3.2) |
Babudieri [21] | 2016 | 5353 | NA | NA | 11.3% | 3.5%/NA | 23,7% | 200 (3.7) |
Masarone et al. [22] | 2020 | 670 | NA | 94.02% | 14.05% | NA/NA | 18.6% | NA |
Fiore et al. [23] | 2021 | 2376 | 42 | 98% | 10.4% | -/NA | 22.6% | 3 (3.6) |
Literature Data | Year | Included PLWH | Age, Median (IQR) | Male Sex | MSM | PWIDs | HCV Co-Infection | HBV Co-Infection | HIV/HCV/HBVCo-Infection |
---|---|---|---|---|---|---|---|---|---|
Pontali et al. [25] | 2008 | 173 | NA | 100% | 1.2% | 91.9% | 90.8% | 6.7% | 6.1 |
Monarca et al. [26] | 2015 | 338 | NA | 97.6% | 4.7% | 51.7% | 55.9% | 6.8% | NA |
Pontali et al. [27] | 2016 | 365 | NA | 100% | 1.8% | 80.5% | 82.7% | 7.1% | 6% |
Sanarico et al. [28] | 2016 | 69 | 43 (31–67) | 95.6% | 2.9% | 78.3% | 81.2% | 81.2% | 69.6% |
Pontali et al. [29] | 2017 | 85 | 48 (NA-NA) | 96.5% | NA | 11.8% | 54.1% | 2.4% | NA |
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Fiore, V.; De Vito, A.; Pontali, E.; Lucania, L.; Madeddu, G.; Babudieri, S. Chronic Viral Hepatitis in the Italian Prison Setting: Prevalence, Outcomes, Literature Needs and Perspectives. Healthcare 2021, 9, 1186. https://doi.org/10.3390/healthcare9091186
Fiore V, De Vito A, Pontali E, Lucania L, Madeddu G, Babudieri S. Chronic Viral Hepatitis in the Italian Prison Setting: Prevalence, Outcomes, Literature Needs and Perspectives. Healthcare. 2021; 9(9):1186. https://doi.org/10.3390/healthcare9091186
Chicago/Turabian StyleFiore, Vito, Andrea De Vito, Emanuele Pontali, Luciano Lucania, Giordano Madeddu, and Sergio Babudieri. 2021. "Chronic Viral Hepatitis in the Italian Prison Setting: Prevalence, Outcomes, Literature Needs and Perspectives" Healthcare 9, no. 9: 1186. https://doi.org/10.3390/healthcare9091186