Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations
Abstract
:1. Introduction
2. Autophagy, Respiratory Infection and Immunity
3. Mechanisms of Autophagy Dysfunction
4. Autophagy Dysfunction in Respiratory Diseases
4.1. Autophagy Defects in Acute Lung Injury (ALI)
4.2. Autophagy Defects in Acute Respiratory Distress Syndrome (ARDS)
4.3. Critical Role of Autophagy in COVID-19 Exacerbations
4.4. Autophagy Defects in COPD
4.5. Autophagy Defects in Cystic Fibrosis
4.6. Autophagy Defects in IPF
5. Autophagy-Mediated CFTR and Immune Response Dysfunction
6. Autophagy-CFTR Dysfunction Induces Acute and Chronic Exacerbations
7. CFTR- Autophagy Dysfunction and Pathogenesis of Chronic Obstructive Lung Diseases
8. Autophagy Augmentation Strategies to Mitigate the Pathogenesis and Progression of Chronic Obstructive Lung Diseases
9. Perspective
Funding
Acknowledgments
Conflicts of Interest
References
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Pehote, G.; Vij, N. Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations. Cells 2020, 9, 1952. https://doi.org/10.3390/cells9091952
Pehote G, Vij N. Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations. Cells. 2020; 9(9):1952. https://doi.org/10.3390/cells9091952
Chicago/Turabian StylePehote, Garrett, and Neeraj Vij. 2020. "Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations" Cells 9, no. 9: 1952. https://doi.org/10.3390/cells9091952