Polyomavirus

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: 1 April 2026 | Viewed by 14

Special Issue Editors


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Guest Editor
Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35205, USA
Interests: cell cycle control during BK polyomavirus infection; DNA damage response during BK polyomavirus infection; BK polyomavirus reactivation following kidney transplant; single-cell virology

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Guest Editor
Department of Molecular Genetics and Biochemistry, The University of Pittsburgh, Pittsburgh, PA 15213, USA
Interests: oncogenic viruses; Merkel cell polyomavirus; circular RNAs; vaccines

Special Issue Information

Dear Colleagues,

Polyomaviruses are small, non-enveloped, double-stranded DNA viruses that cause lifelong persistent infection without clinical symptoms in healthy people but can result in significant morbidity and mortality in immunocompromised individuals. Understanding how these viruses are transmitted, how their genomes are maintained in various cell types, and how their reactivation can cause pathogenesis and/or cancer has been the subject of rigorous study for decades. The size of this virus makes it dependent upon host pathways, and its lifelong persistence suggests immune evasion mechanisms.

Human polyomaviruses such as BK and JC are associated with serious diseases in immunocompromised individuals such as polyomavirus nephropathy, hemorrhagic cystitis, and progressive multifocal leukoencephalopathy. Merkel cell polyomavirus can cause Merkel cell carcinomas in elderly patients.

This Special Issue, titled “Polyomavirus”, will provide the most up-to-date insights into virus–host interactions, pathology, phylogeny, immune response, and structure function relationships for Simian virus 40, BK polyomaviruses, JC polyomaviruses, Merkel cell polyomaviruses, and murine polyomavirus, as well as newly discovered polyomaviruses. Scientists worldwide are welcome to contribute original research papers, brief reports, technical notes, and reviews to share current models in the field. We aim to cover both recent and historical advances in the field of polyomavirus DNA tumor viruses.

Dr. Sunnie R. Thompson
Prof. Dr. Patrick S. Moore
Guest Editors

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Keywords

  • virus–host interactions
  • viral life cycle
  • viral replication
  • pathogenesis
  • phylogeny
  • structure
  • transcription
  • packaging
  • trafficking
  • persistence
  • re-arrangements
  • gene regulation
  • reactivation
  • miRNA
  • viral immune evasion
  • vaccines

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Published Papers

This special issue is now open for submission.
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