Conferences
6–7 September 2018, Natcher Conference Center, National Institute of Health, Bethesda, Maryland
2018 Chromatin Control of Viral Infection
Like their cellular hosts, invading viral pathogens that depend upon the host cell nuclear machinery are also subject to the regulatory impacts of chromatin.
For lytic pathogens, successful infection depends upon the ability to counter cellular defense mechanisms that can result in suppressive heterochromatin assembled on the viral genome along with utilization of cellular chromatin modulation activities that promote efficient viral gene transcription and DNA replication. Additionally, viral pathogens whose complex replication cycles include coupled stages of lytic replication and latency/persistence are impacted by epigenetic modulation that plays a controlling role in determining the viral state.
Research into the basic biology of chromatin deposition, modification, and modulation/remodeling will contribute to the understanding of the complex host-viral interactions that influence the progression of viral diseases. Additionally, insights into the role of epigenetic machinery in controlling viral infection can present novel opportunities for prophylaxis or treatment. The workshop "2018 Chromatin Control of Viral Infection" will focus on epigenetic mechanisms that regulate viral chromatin states, viral encoded factors that modulate viral and/or cellular chromatin, and epigenetic control of host cell antiviral responses.
We invite you to participate in this intimate symposium-workshop.
Registration and additional information online at:
