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Transplantology
Special Issues
2022 Selected Papers from Transplantology Editorial Board Members
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2022 Selected Papers from Transplantology Editorial Board Members

A special issue of Transplantology (ISSN 2673-3943).

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 3152

Special Issue Editors

Dr. Laura Iop

E-Mail Website
Guest Editor
Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua, I-35128 Padua, Italy
Interests: transplantation; stem cells; regenerative medicine; bioengineering; medical technologies; disease modeling
Prof. Dr. Giuseppe Lucarelli

E-Mail Website
Guest Editor
Andrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation—Urology, University of Bari “Aldo Moro”, 70124 Bari, Italy
Interests: kidney cancer; prostate cancer; kidney transplantation; metabolomics
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Constança Figueiredo

E-Mail Website
Guest Editor
Institute for Transfusion Medicine and Transplant Engineering, Carl‐Neuberg‐Strasse 1, D‐30625 Hannover, Germany
Interests: transplantation; cell and gene therapy; immunology; histocompatibility
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of Transplantology is dedicated to recent advances in the research areas of transplantation and will comprise a diverse selection of exclusive papers written by the Editorial Board Members (EBMs). Both original research articles and comprehensive review papers are welcome.

The papers will be published free of charge, with full open access after peer review.

Dr. Laura Iop
Prof. Dr. Giuseppe Lucarelli
Prof. Dr. Constança Figueiredo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Transplantology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

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9 pages, 1356 KiB  
Brief Report
Non-Invasive Diagnosis of Pediatric Intestinal Graft-Versus-Host Disease: A Case Series
by Manuela Spadea, Francesco Saglio, Anna Opramolla, Caterina Rigazio, Fabio Cisarò, Massimo Berger, Paola Quarello, Pier Luigi Calvo and Franca Fagioli
Transplantology 2022, 3(2), 115-123; https://doi.org/10.3390/transplantology3020012 - 29 Mar 2022
Viewed by 2607
Abstract
Intestinal graft-versus-host disease (I-GvHD) represents a life-threatening complication in allogeneic stem cell transplantation (SCT). Unfortunately, non-invasive validated diagnostic tools to diagnose I-GvHD, evaluate treatment response, and guide the duration of immunosuppression are still lacking. We employed standard ultrasound and power Doppler to diagnose [...] Read more.
Intestinal graft-versus-host disease (I-GvHD) represents a life-threatening complication in allogeneic stem cell transplantation (SCT). Unfortunately, non-invasive validated diagnostic tools to diagnose I-GvHD, evaluate treatment response, and guide the duration of immunosuppression are still lacking. We employed standard ultrasound and power Doppler to diagnose and follow up on pediatric intestinal GvHD. We herein report on three patients, prospectively evaluated among 24 pediatric patients referred to our center for allogeneic SCT. These three patients presented abdominal pain and diarrhea within the first 200 days after transplantation. In the reported cases, we performed small- and large-intestine ultrasound (US) at clinical onset of lower-intestinal symptoms and, when intestinal GvHD was confirmed, at GvHD flares, if any, and at follow-up. US constantly (3/3 patients) revealed increased bowel wall thickening (BWT) with different bowel segments’ involvement from patient to patient. Further, a moderate or strong increased Doppler signaling was seen in 2 out of 3 patients, according to clinical GVHD staging (e.g., the more the increase, the more the staging). Standard sonography corroborated GvHD diagnosis in all patients considered and was able to detect GvHD progression or complete normalization of findings, thus simplifying ensuing clinical decisions. Our report highlights the need to design clinical trials for the validation of non-invasive radiologic tools for diagnosis and follow-up of GvHD, especially in pediatric patients. Full article
(This article belongs to the Special Issue 2022 Selected Papers from Transplantology Editorial Board Members)
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