Special Issue "Neuropsychological Studies of Mild Cognitive Impairment (MCI), Mild Dementia and Depression in Older Adults"

A special issue of Psych (ISSN 2624-8611). This special issue belongs to the section "Neuropsychology".

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 1185

Special Issue Editors

Dr. Mark Stemmler
E-Mail Website
Guest Editor
Deparmtent of Psychology; Univeristy of Erlangen-Nuernberg, 91054 Erlangen, Germany
Interests: quantitative methods; categorical data analysis; evaluation research; human development; prevention; cognitive assessment; juvenile delinquency
Dr. Hartmut Lehfeld
Guest Editor
Department of Psychiatry and Psychotherapy, Paracelsus Medical University, 90419 Nürnberg, Germany
Interests: Alzheimer's disease; gerontology; neurodegeneration; clinical neuropsychology; cognition disorders; memory; neuropsychological assessment; clinical psychology; cognitive psychology; neuroscience

Special Issue Information

Dear Colleagues,

Dementia and depression are the most frequent psychiatric disorders of old age. Both affect the quality of life of patients in a significant way and to a much greater extent than many somatic diseases. Depression is also considered a serious risk factor for developing dementia. In addition, dementia and depression share a diagnostic deficit. Dementia is often only diagnosed in more advanced stages, showing higher degrees of functional impairment. Worldwide, patients suffering from depression are frequently not correctly diagnosed; therefore, in many countries, less than 10% of depressed subjects receive adequate treatment.

Due to an overlap in symptoms, a valid differential diagnosis between dementia and depression is sometimes difficult to establish: Depressive disorders in old age are associated with cognitive impairment in 40% to 60% of patients. Conversely, about 40% of dementia patients develop depression symptoms. Accordingly, among the differential diagnoses of dementia, the ICD-10 lists depressive disorders in the first place, which can show characteristics of incipient dementia with memory impairment, slowed thinking, and lack of spontaneity. In the same way, the DSM-5 recommends inspecting the cognitive profiles of patients suggesting memory and executive impairment as typical for Alzheimer’s disease, whereas nonspecific and more diverse test performance could be expected in major depression. In accordance with this perspective, a number of reviews state a lack

of clarity in the neuropsychological profiles of depressive disorders. Since the cognitive deficits associated with depression are less pronounced than those found in dementia, a differential diagnosis becomes much more difficult when it is not a full-blown dementia, but mild cognitive impairment (MCI) must be differentiated from depression.

The goal of this Special Issue is to shed light on the diagnostic profiles and differential diagnosis of depression, MCI, and mild dementia. The findings will contribute significantly to the more precise diagnosis of depression and cognitive impairment in older adults.

Dr. Mark Stemmler
Dr. Hartmut Lehfeld
Guest Editors

Manuscript Submission Information

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  • neuropsychology
  • mild cognitive impairment (MCI)
  • differential diagnosis of depression and MCI
  • diagnostic profiles
  • mild dementia
  • activities of daily living (ADL)

Published Papers (1 paper)

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The Application of the SKT Short Cognitive Performance Test to English-Speaking Populations
Psych 2021, 3(4), 717-727; https://doi.org/10.3390/psych3040046 - 24 Nov 2021
Cited by 1 | Viewed by 683
The SKT (Syndrom-Kurz-Test) is a well-established short cognitive performance test for the detection of attention and memory deficits in Germany. The goal of this paper is to test whether the SKT could be applied to English-speaking populations to screen cognitive impairments in the [...] Read more.
The SKT (Syndrom-Kurz-Test) is a well-established short cognitive performance test for the detection of attention and memory deficits in Germany. The goal of this paper is to test whether the SKT could be applied to English-speaking populations to screen cognitive impairments in the US, Australia, and Ireland. A regression-based continuous norming technique was applied. Standardized test results obtained from German-speaking (n = 1056) and English-speaking (n = 285) samples were compared. Both samples consisted of cognitively unimpaired, community-dwelling, and independently living volunteers (non-patients) over 60 years of age. Means, medians, and standard deviations of raw scores were calculated. A high similarity in the raw value distributions of the criterion variables and a comparison of German and English multiple regression residuals indicated the equivalence among the samples. In addition, the obtained multiple regression equations for predicting the subtest scores including the explained variances (R2) were highly comparable. Age and intelligence turned out to be the most important and necessary predictors for each subtest performance. The results suggest that the new regression-based norming of the SKT can be validly used in the three English-speaking countries. Full article
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