Organoids in Organ-on-Chip Approach
A special issue of Organoids (ISSN 2674-1172).
Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 8067
Special Issue Editors
Interests: lab-on-chip; polymer microfabrication technologies; integrated microchips with optical and electrochemical detection; point of care tools; organ-on-chip; tools for drug screening; toxicology research; nanomaterials
Interests: cell-on-chip; organ-on-a-chip; tumor micro-environment; multi-organ-on-chip; cancer research; metastasis; cellular response to cancer therapy; nanomaterials in anticancer studies; liver toxicology
Special Issue Information
Dear Colleagues,
Organ-on-Chip (OoC) models present new possibilities in reproducing the physiological and pathological states of the human body. Models of this type show great potential in better summarizing the main characteristics of real human organs in terms of organ-specific cell types, tissue architecture and function. Moreover, OoC models are an alternative to conventional monolayer cell culture and animal models in biomedical research, while filling the gap between a single cell and an organism in model systems of human physiological and pathological states. In addition, the combination of OoC techniques with organoids can serve as personalized disease models in precision medicine, e.g., in revealing disease mechanisms, testing personalized clinical therapies and in evaluating drug candidates.
The aim of this Special Issue of Organoids is to present new reports that advance knowledge regarding the use of organoids in Organ-on-Chip systems. We welcome the submission of scientific articles and reviews that focus on aspects of organ modeling, disease modeling or drug screening examples using these two approaches.
Prof. Dr. Zbigniew Brzozka
Dr. Agnieszka Żuchowska
Guest Editors
Manuscript Submission Information
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Keywords
- organoid
- organ-on-chip
- drug screening
- organ in vitro
- 3D cell culture
- microfluidic
- organ modeling
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