Oral Lichen Planus: Diagnostic, Prognosis and Management Strategies

A special issue of Oral (ISSN 2673-6373).

Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 4685

Special Issue Editor


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Guest Editor
Dental School, The University of Western Australia, Nedlands, WA 6009, Australia
Interests: dental public health; periodontology; oral health; oral potentially malignant disorders; oral cancers

Special Issue Information

Dear Colleagues,

Oral lichen planus is a relatively common chronic mucocutaneous disease that affects up to 2% of the general population. Despite that, this condition is associated with historical controversies about its pathological behaviors, as oral lichen planus lacks specific diagnostic features.

Thus, some oral lesions with a genuinely high risk of malignancy have been misdiagnosed as oral lichen planus, which to some extent has contributed to highly variable rates of oral lichen planus malignant transformation in the literature.

This in turn impacted the patient’s quality of life by either over- or under-estimating the oral lichen planus risk of malignancy.

This Special Issue aims to provide a deep insight into approaches that improve the management of oral lichen planus patients based on evidence-based findings.

Considering that, this issue invites you to publish your findings according to the following themes:

  • Oral lichen planus diagnostic criteria (suggestions, modifications, validations).
  • Diagnostic aids for objective oral lichen planus diagnosis.
  • Use of artificial intelligence for oral lichen planus diagnosis.
  • Oral lichen planus and risk of malignant transformation.
  • Biomarkers to predict the potential risk of malignancy.
  • Oral lichen planus and quality of life.
  • Oral lichen planus management protocols and strategies.

Invited studies on these themes include original research articles, reviews, short communications, case series, and case reports.

Dr. Majdy Idrees
Guest Editor

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Keywords

  • oral lichen planus
  • diagnosis
  • malignant transformation
  • management protocols
  • diagnostic aids
  • quality of life

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Published Papers (1 paper)

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12 pages, 744 KiB  
Systematic Review
Malignant Transformation of Oral Lichen Planus—An Umbrella Study of Systematic Reviews
by Saman Warnakulasuriya, Pablo Ramos-García and Miguel Ángel González-Moles
Oral 2023, 3(3), 295-306; https://doi.org/10.3390/oral3030024 - 3 Jul 2023
Cited by 9 | Viewed by 3907
Abstract
Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation. We conducted an umbrella study of published systematic reviews. An extensive English-language study search was carried [...] Read more.
Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation. We conducted an umbrella study of published systematic reviews. An extensive English-language study search was carried out in several databases to identify relevant articles, providing systematic reviews on the malignant transformation of OLP. Data from eight systematic reviews published between 2014 and 2023 are presented. The reported proportions of malignant transformation ranged from 1.1% to 1.4%. A meta-analysis based on the 10 highest-quality studies yielded a higher proportion of malignant transformation (2.28%). We list some limitations found in several of these systematic reviews. Some studies reported an increased risk of malignancy in OLP lesions, demonstrating epithelial dysplasia. In view of the consistent evidence of the risk of oral malignancy, OLP patients should be monitored carefully to detect early cancer development. Full article
(This article belongs to the Special Issue Oral Lichen Planus: Diagnostic, Prognosis and Management Strategies)
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