Special Issue "Application of Glycobiology in the Treatment of Diseases"
A special issue of Medicines (ISSN 2305-6320).
Deadline for manuscript submissions: 31 August 2019.
Prof. Dr. Vitor H. Pomin
Department of BioMolecular Sciences, Pharmacognosy division, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, USA
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Phone: +1 (662) 915-3114
Interests: biological chemistry, structural biology, glycobiology, NMR spectrocopy, sulfated glycans, glycosaminoglycans, marine medicinal glycomics, interactomics, glycosaminoglycan–protein interactions
Glycobiology is a branch of science aimed at understanding the structure and function of carbohydrates and/or glycosylated compounds. It was previously believed that carbohydrates were biomolecules mainly responsible for storing energy, like glycogen and starch in animals and plants, or to serve as structural components, like chitin on the exoskeleton of insects and mollusks, and cellulose on the cell walls of plants and algae. This limited conception has been considerably enlarged over the last decades as the number of glycans and glycoconjugate structures have been revealed and associated with their various functions in biology and with their potential uses in medicine. Today, a series of functional glycans and glycoconjugates are widely studied in many scientific laboratories around the world. The research not only concerns the structural variations of carbohydrates, but also the functional roles and/or the beneficial effects of these molecules in various human diseases, such as inflammation, coagulation, thrombosis, cancer, microbial infections and neuronal disorders. Examples of carbohydrates under intense investigation today are the N- or O-linked glycoproteins, glycolipids, glycosaminoglycans, proteoglycans and marine glycans like chitosan and sulfated polysaccharides. The impact of glycobiology on medicine has grown so intensively lately that even certain academic courses such as medicine, pharmacy, biology, biochemistry and chemistry, are now incorporating glycobiology as a separate subject in their curricula. Besides this, new international research programs related to this science have been developed. Examples of these projects include glycomics, medicinal glycomics, glycosaminoglycanomics, glycoproteomics and others. In this Special Issue, research and review papers are presented to enlighten the discussion about the potential therapeutic applications of carbohydrates.
Prof. Dr. Vitor H. Pomin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicines is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- N-linked glycans
- O-linked glycans
- Sulfated fucans
- Sulfated galactans