Post-Translational Modification of ABC Transporters in Health and Disease
A special issue of Kinases and Phosphatases (ISSN 2813-3757).
Deadline for manuscript submissions: 30 March 2025 | Viewed by 93
Special Issue Editor
Interests: cystic fibrosis; cystic fibrosis transmembrane conductance regulator (CFTR); chloride channel
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
ABC transporters play crucial roles in physiological processes, and their dysregulation is linked to various human diseases, including cystic fibrosis. The expression and function of these transporters are regulated by post-translational modifications, such as phosphorylation, ubiquitination, and sumoylation. Gaining a deeper understanding of the regulatory mechanisms that control ABC transporter expression and function through post-translational modifications is essential for elucidating disease pathologies and developing therapeutic strategies.
In this Special Issue, we invite original research articles, commentaries, and reviews on all aspects of post-translational modifications of ABC transporters, with a particular focus on the following topics:
- Post-translational modifications that regulate the expression and function of ABC transporters;
- Enzymes involved in the regulation of ABC transporter expression and function;
- Pharmacological agents targeting post-translational modifications of ABC transporters;
We look forward to receiving contributions on these topics and other related areas identified by the many researchers investigating the post-translational modifications of membrane proteins.
Prof. Dr. Tsukasa Okiyoneda
Guest Editor
Manuscript Submission Information
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Keywords
- ABC transporter
- ubiquitin
- sumo
- ubiquitin-like modifiers
- deubiquitinase
- membrane protein
- post-translational modification
- membrane protein
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