Emerging Advances in Cardiac Electrophysiology: Mapping, Ablation, and Novel Technologies

Dear Colleagues,

Cardiac electrophysiology is undergoing a paradigm shift driven by disruptive technologies that are reshaping arrhythmia diagnosis, mapping, and ablation. High-density mapping systems, ultra-fast imaging modalities, and advanced computational algorithms now enable unprecedented visualization of complex atrial and ventricular substrates, fostering a precision-guided approach to arrhythmia management. Simultaneously, novel energy sources—such as pulsed-field ablation (PFA), ultra-low temperature cryoablation, and hybrid techniques—are redefining procedural efficacy and safety. These advancements, coupled with the integration of artificial intelligence, real-time image fusion, and multimodal signal processing, are accelerating workflows, improving patient selection, and enhancing long-term outcomes.

This Special Issue will bring together cutting-edge research, expert reviews, and clinical insights on the latest breakthroughs in cardiac electrophysiology. Priority topics include advanced substrate mapping techniques, innovations in ablation energy sources, personalized arrhythmia therapy, peri-procedural imaging integration, and outcome-driven device technologies. By uniting the perspectives of clinicians, engineers, and data scientists, we aim to create a comprehensive platform that explores current achievements, identifies unmet clinical needs, and defines the roadmap for future innovation. Through this Special Issue, we aspire to bridge technology and clinical practice, accelerating the safe and effective translation of novel electrophysiological tools into transformative patient care.

Dr. Michael Spartalis
Guest Editor

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