Machine Learning and Simulation for Public Health

A special issue of Information (ISSN 2078-2489). This special issue belongs to the section "Information Processes".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 590

Special Issue Editors


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Guest Editor
Department of Computer, Control and Management Engineering, Sapienza Università di Roma, Rome, Italy
Interests: nonlinear systems and control; discrete and hybrid control; analysis; control applications; dynamic sensor networks; sampled data systems; machine learning for system modelling
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Computer, Control and Management Engineering, Sapienza Università di Roma, Rome, Italy
Interests: analysis, identification and control of biomedical systems; epidemic modelling and control; optimal control for resource management
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Machine learning is becoming a key instrument in public health, offering innovative solutions for analysing complex datasets and supporting decision-making at both clinical and population levels. Modern health challenges generate vast amounts of heterogeneous data, from electronic health records to genomic sequences and from environmental exposures to social determinants of health. Machine learning can capture nonlinear relationships within these diverse sources and uncover predictive patterns that guide interventions.

An important example of the contribution of machine learning is in surveillance and early detection: predictive models trained on real-time demographic and health data can anticipate outbreaks before they become clinically evident, allowing timely interventions and more efficient allocation of resources. At the same time, algorithms that integrate genetic, behavioural, and environmental information enable the design of targeted prevention strategies, strengthening the bridge between individual care and population health policy. The adoption of these tools, however, raises challenges regarding data quality, interpretability, and fairness.

Soon, machine learning in public health is expected to benefit from real-time data streams generated by wearable devices and mobile health applications, offering continuous monitoring of population well-being. All these developments suggest that machine learning will soon become a cornerstone of proactive, data-informed public health strategies.

Alongside this fast expansion of machine learning approaches in public health applications, the present Special Issue aims at representing a reference point both for the state of the art and for suggesting and presenting possible lines of developments.

Dr. Paolo Di Giamberardino
Dr. Daniela Iacoviello
Guest Editors

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Keywords

  • machine learning
  • public health
  • health data analytics
  • population health management
  • data-driven healthcare
  • wearable devices
  • disease surveillance

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Published Papers (1 paper)

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Research

28 pages, 8399 KB  
Article
Machine Learning-Enabled Secure Unified Framework for Remote Electrocardiogram Monitoring via a Multi-Level Blockchain System
by Chathumi Samaraweera, Dongming Peng, Michael Hempel and Hamid Sharif
Information 2026, 17(4), 383; https://doi.org/10.3390/info17040383 - 18 Apr 2026
Viewed by 320
Abstract
Timely classification of cardiovascular diseases is crucial to improve medical outcomes. Emerging remote patient monitoring systems help achieve this by enabling continuous monitoring of electrocardiogram signals in home environments. However, these systems struggle with unique challenges like missing genuine medical emergencies, rising energy [...] Read more.
Timely classification of cardiovascular diseases is crucial to improve medical outcomes. Emerging remote patient monitoring systems help achieve this by enabling continuous monitoring of electrocardiogram signals in home environments. However, these systems struggle with unique challenges like missing genuine medical emergencies, rising energy demands, scalability challenges, handling vast medical databases, data processing delays, and safeguarding patient records. To overcome these challenges, we propose a single framework with three main phases: (a) an embedded hardware-driven K-Nearest Neighbor (KNN)-assisted real-time ECG monitoring and classification method; (b) a differentiated communication strategy (DCS) formed with a priority-based ECG data packaging framework and multi-layered security protocols; and (c) a multi-level blockchain network (MLBN) architecture armed with adaptive security mechanisms and real-time cross-chain medical data communication bridges. Simulations are conducted using the ECG signals (1000 fragments) dataset and the Ganache Ethereum development framework. The classification accuracies obtained for patient urgent categories U1 to U5 are 91.43%, 95.71%, 94.23%, 90.00%, and 91.43%, respectively. The performance evaluation results of the KNN-guided classification method, along with DCS and MLBN simulation results obtained from average gas consumption analysis, confirms reliability and viability of our framework, while also revolutionizing remote patient monitoring technology and addressing critical challenges in existing systems. Full article
(This article belongs to the Special Issue Machine Learning and Simulation for Public Health)
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