Microarrays in Non-Coding RNAs Profiling
A special issue of High-Throughput (ISSN 2571-5135).
Deadline for manuscript submissions: closed (30 April 2018) | Viewed by 520
Special Issue Editor
Interests: bioinformatics; cardiovascular; circRNA; database; epitranscriptomics; lncRNA; miRNA; non-coding RNA
Special Issue Information
Dear Colleagues,
The presence of non-coding RNAs (ncRNAs) is firmly fixed in various fields to overturn the previous concepts of junk DNA and transcriptional noise. Many ncRNAs have been shown to be functional as in the case of microRNAs (miRs) and more recent long non-coding RNAs (lncRNAs). It is predicted that the number of ncRNAs well surpasses that of protein-coding genes as organisms become more complex. Given such complexity, it is suggested that ncRNAs could be a key to decipher yet unknown mechanisms of physiological processes and disease status. Although the emergence of next generation sequencing (NGS) technology revolutionized the way genomics and transcriptomics studies are conducted, the past generation technology microarray still outperforms NGS for its specificity and easy of data analysis, which is increasing noted by computational challenges due to the increased high-throughput of NGS resulting in avalanche of data. In this Special Issue, we would like to revisit the power of microarrays in profiling of ncRNAs to facilitate further functional studies of exciting molecules that hold more functions to be discovered.
Dr. Shizuka Uchida
Guest Editor
Manuscript Submission Information
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Keywords
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algorithm
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bioinformatics
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circRNA
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detection method
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lncRNA
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microarray
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software
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