From Pain to Gain: A Multidisciplinary Pathway to Recovery, Resilience, and Vitality

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Healthcare Quality, Patient Safety, and Self-care Management".

Deadline for manuscript submissions: 15 December 2026

Special Issue Editor


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Guest Editor
Department of Orthopaedics & Rehabilitation, Yale School of Medicine, Yale University, New Haven, CT 06510, USA
Interests: injury prevention; musculoskeletal health & rehabilitation; integrative systems based approaches to movement and recovery; resilience, functional performance and health span optimization; translational frameworks connecting clinical practice

Special Issue Information

Dear Colleagues,

Pain is a multi-dimensional experience that extends far beyond nociception, influencing physical function, sleep, stress, nutrition, psychosocial well-being, and quality of life. If inadequately addressed, pain may reinforce a degenerative cascade in which reduced activity, inadequate sleep, increased stress, poor diet, weight gain, and social withdrawal reinforce one another, ultimately amplifying pain and accelerating functional decline. Traditional pain management strategies have focused on single modalities or symptom reduction alone, which fall short in optimizing long-term function for optimized health span.

This Special Issue, “From Pain to Gain: A Multidisciplinary Pathway to Recovery, Resilience, and Vitality”, aims to advance a holistic, multi-dimensional, skills-based perspective on pain recovery, emphasizing interdisciplinary strategies to promote optimal function. Central to this approach is the concept of skill synergy, wherein health behaviors such as movement, sleep hygiene, stress management, and social engagement are learnable skills that interact synergistically to reverse the downward spiral associated with pain. By targeting multiple domains simultaneously, integrated interventions generate upward momentum towards recovery and sustained health. 

We invite contributions spanning integrated conceptual frameworks, intervention studies, and research bridging discovery and practice that explores pain through a wide lens from multiple angles. Work linking contemporary pain experiences with evolutionary perspectives, showing how ancestral adaptations influence suffering and recovery, is especially encouraged. Topics of interest include rehabilitation and physical activity, lifestyle and nutritional interventions, sleep and stress regulation, psychosocial determinants of recovery and personalized, patient-centered outcomes. Collectively, we seek holistic strategies that enable individuals to reclaim capacity, resilience, and vitality.

Dr. Bohdanna Zazulak
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pain management
  • rehabilitation
  • exercise therapy
  • functional recovery
  • biopsychosocial model
  • integrated care
  • physical therapy
  • lifestyle modification
  • quality of life
  • health behavior

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Published Papers

This special issue is now open for submission.
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