Central Sensitization Syndromes: Relevance of Psychological Factors in the Genesis, Maintenance and Intervention

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 1 June 2026

Special Issue Editors


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Guest Editor
Department of Personality, Assessment and Psychological Treatment, University of Granada. Cartuja Campus, 18071 Granada, Spain
Interests: clinical and health psychology; personality; psychological disorders; gender-based violence; socio-emotional skills; cognitive-behavioral therapy; evidence-based psychological intervention

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Guest Editor
Mind, Brain and Behavior Research Center (CIMCYC), University of Granada, Campus Universitario de Cartuja, 18011 Granada, Spain
Interests: gender-based violence; socio-emotional skills; evidence-based psychological therapy; penitentiary psychology; psychological assessment; ethics in psychology

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Guest Editor
Department of Personality, Assessment and Psychological Treatment. Faculty of Psychology. University of Granada. Cartuja Campus, 18071 Granada, Spain
Interests: Chronic pain; fibromyalgia; psychophysiology of sleep; assessment and treatment of emotional disorders; post-traumatic stress disorder; cognitive-behavioral therapy; evidence-based psychological intervention

Special Issue Information

Dear Colleagues,

Central sensitization syndromes (CSSs) constitute a heterogeneous set of conditions characterized by an increased reactivity of nociceptive neurons in the CNS that significantly impact the pain experience. Although fibromyalgia is considered a prototype of CSSs, many other conditions (e.g., chronic fatigue syndrome, irritable bowel syndrome, migraine/tension headache) fall under this label. In addition to alodinia, hiperalgesia, and hypersensitivity, CSSs share other annoying symptoms such as fatigue, insomnia, and emotional disorders, all of which lead to an important loss of quality of life. Multiple psychological factors can affect the experience of individuals with CSSs; however, there are still many gaps in our knowledge regarding how these psychological factors act, how they interact with neurobiological and contextual factors, and which are key in the prediction of individual risk, the development/maintenance of the clinical condition, and response to psychological intervention.

 

We are pleased to announce a Special Issue focused on “Central Sensitization Syndromes: Relevance of Psychological Factors in the Genesis, Maintenance, and Intervention”. This Special Issue aims to provide a platform for researchers and professionals of mental health to contribute with their knowledge, experience, and best practices to improve the understanding and management of CSSs.

 

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following: the identification and psychological assessment of vulnerability, maintenance and protective factors (e.g., maladaptive cognitive–affective processes, personality and psychopathology, trauma and psychosocial stress, coping strategies, psychosocial support); psychological therapy aimed at improving symptoms and daily functioning (e.g., psychoeducation, cognitive–behavioral therapy, acceptance and mindfulness interventions, emotional regulation); and therapy focusing on the geriatric, adult, or child populations who have or are at risk of developing CSSs.

 

We look forward to receiving your valuable contributions.

Guest Editors

Prof. Dr. M. Pilar Martínez, Prof. Dr. Ana I. Sánchez, and Prof. Dr. Elena Miró 

Prof. Dr. María Pilar Martínez
Prof. Dr. Ana Isabel Sánchez Gómez
Prof. Elena Mirõ
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Central sensitization syndromes
  • cognitive, emotional and behavioral variables
  • vulnerability or risk
  • maintenance factors
  • protective factors
  • assessment and psychological treatment.

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Published Papers

This special issue is now open for submission.
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