Evolution of Non-coding Elements in Genome Biology
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Population and Evolutionary Genetics and Genomics".
Deadline for manuscript submissions: 25 August 2024 | Viewed by 1414
Special Issue Editor
Special Issue Information
Dear Colleagues,
The evolutionary process through which species mutate to change their heritable characteristics over time is one of the most fundamental processes that govern biological life on earth. While some mutational changes occur in gene coding regions, the vast majority occur in the non-coding portion of the genome, which contains many transposable elements and DNA repeats. Recent improvements in DNA sequencing and computational analysis are starting to reveal the role of these regions in the cis-regulation of gene expression. What is becoming apparent is that these changes can alter the binding of transcription factors and their chromatin regulators to change genome organization and function. In addition, genome-wide association studies have shown that a large number of disease-associated variants reside in these noncoding sequences.
With this Special Issue, we will be focussing on the recent advances achieved in our understanding of the evolution of non-coding elements in genome biology. We encourage submissions that discuss novel findings or concepts concerning the structure, function, organisation and expression of genomes in the context of their relationship with either cis-regulatory transposable elements, natural genome diversity or disease progression.
Dr. David Lando
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- genome organisation
- evolution
- non-coding
- transposable element
- chromatin
- cis-regulatory element
- enhancer
- transcription factor
