Selective Autophagy in Aging and Disease
A special issue of Diseases (ISSN 2079-9721).
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 8599
Special Issue Editor
2. UO Laboratorio di Morfologia Umana Applicata, IRCCS San Donato, 20133 Milan, Italy
Interests: translational preclinical models of diseases; metabolic diseases; oxidative damage; endoplasmic reticulum stress; mitochondria; autophagy; mitophagy; role of antioxidants; ageing; sirtuins; natural compounds to limit metabolic diseases; cardiovascular damage and sirtuins modulation; obesity and mitochondrial endoplasmic reticulum interplay; selective autophagy in aging and disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
“Recycling and dismantling” are fundamental words to keep our environment clean but they are also suitable for the inner cellular environment involving autophagy. In past years, more research has been performed on a specific or random autophagy (called macroautophagy or chaperone-mediated autophagy). Currently, the definitive digestion of excessive dismantled materials, dysfunctional organelles, or pathogens (bacteria and virus) is analyzed via a specific cargo-recognition mechanism called “selective autophagy”. Selective autophagy is largely conserved from yeast to human cells and is rapidly emerging as a crucial mechanism to maintain homeostasis and well-being. Thus, aberrant selective autophagy, if excessive or reduced, may occur in human inflammatory, degenerative or metabolic diseases and cancer. This Special Issue aims to exchange ideas in the field, to collect original research and review articles, and to extend the knowledge of extraordinary cellular signaling and its regulation from bench to bedside.
As such, your indispensable scientific contributions on new stimulating resources in the fascinating field of autophagy are eagerly awaited.
Dr. Alessandra StacchiottiGuest Editor
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Keywords
- Mitophagy
- Pexophagy
- Xenophagy
- ER-phagy
- Cardiovascular diseases
- Metabolic diseases
- Neurodegenerative diseases
- Cancer
- COVID-19
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