Gerontopsychiatry: Research, Perspectives, Innovation and Progress in Geriatric Psychiatry

A Special Issue of Diseases (ISSN 2079-9721) belonging to the section "Neuro-psychiatric Disorders".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 639

Editors


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Guest Editor
Medical Department, Faculty of Medicine and Pharmacy, Dunărea de Jos University, 800008 Galati, Romania
Interests: anxiety disorders; depression; psychiatry; serotonin; addiction; mental health care; stigma; oral health and psychiatry; diabetes and mental health; therapeutic relationship; psychosomatics
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Guest Editor
1. Department of Geriatric Medicine, Amiens University Hospital, 80021 Amiens, France
2. Laboratory of Functional Neurosciences UR 4559, University of Picardie—Jules-Verne, F-80000 Amiens, France
Interests: neurocognitive troubles; ageing; psychotropic drugs; behavioral symptoms; non-pharmacological interventions

Special Issue Information

Dear Colleagues,

The global population is undergoing a significant demographic shift that is marked by unprecedented aging. This trend presents profound challenges and opportunities for mental healthcare. Gerontopsychiatry, the field dedicated to the mental health of older adults, is at the forefront of this challenge, addressing complex conditions where neurobiological aging, cognitive decline, and psychiatric symptomatology intersect. As the prevalence of late-life mental disorders—from dementia to depression and anxiety—continues to rise, the need for cutting-edge research, novel therapeutic strategies, and updated clinical models has never been more urgent.

We are pleased to invite you to contribute your work to our Special Issue, “Gerontopsychiatry: Research, Perspectives, Innovation and Progress in Geriatric Psychiatry.” The aim of this Special Issue is to create a comprehensive forum for the dissemination of high-impact research in geriatric mental health. We seek to bridge the gap between burgeoning neuroscience discoveries and their practical, clinical applications. The focus is twofold: to capture novel “Perspectives” (e.g., new theoretical models, etiological insights, or diagnostic refinements) and to showcase "Innovation" (e.g., technological advancements, novel therapeutics, and pioneering models of care delivery). This initiative aligns directly with the journal's core scope of advancing translational and clinical science in psychiatry to improve patient outcomes.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Diagnostics and perspectives for neurocognitive and late-life mood disorders.
  • Digital health, AI, and technological innovations in geriatric mental healthcare.
  • Advances in psychopharmacology and non-pharmacological interventions for older adults.
  • Healthy and pathological aging.
  • New models of integrated (collaborative) care for gerontopsychiatry.
  • Social determinants, loneliness, and cultural factors in geriatric mental health.
  • Translational research linking basic neuroscience to clinical geropsychiatry.

We look forward to receiving your contributions,

Dr. Lavinia-Alexandra Moroianu
Prof. Dr. Frédéric Bloch
Guest Editors

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Keywords

  • gerontopsychiatry
  • aging
  • innovation
  • neurocognitive disorders
  • late-life depression
  • digital health
  • neuroinflammation
  • integrated care
  • resilience

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Published Papers (1 paper)

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43 pages, 2198 KB  
Systematic Review
Oral Structural and Functional Impairment in Relation to Depressive Outcomes in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies
by Lavinia-Alexandra Moroianu, Laurentiu Dragus, Stefan Rosca, Magdalena Rusu Negraia, Valeriu Ardeleanu, Rares Nicolae Vadana, Ionelia State, Georgel Mihu, Madalina Nicoleta Matei and Simona Dana Mitincu Caramfil
Diseases 2026, 14(9), 309; https://doi.org/10.3390/diseases14090309 - 26 Aug 2026
Viewed by 202
Abstract
Background/Objectives: Oral structural and functional impairment and depressive outcomes frequently coexist in older adults, but the strength and interpretation of their association remain uncertain. This systematic review and meta-analysis evaluated whether poorer oral status or function is associated with depressive outcomes in older [...] Read more.
Background/Objectives: Oral structural and functional impairment and depressive outcomes frequently coexist in older adults, but the strength and interpretation of their association remain uncertain. This systematic review and meta-analysis evaluated whether poorer oral status or function is associated with depressive outcomes in older populations. Methods: Six databases were searched for observational studies published from 1 January 2016 to 5 January 2026, with an update on 19 April 2026. Eligible studies examined oral impairment as the exposure and depressive outcomes as the endpoint in older adults. Risk of bias was assessed using Newcastle–Ottawa criteria and certainty using GRADE. Comparable adjusted odds ratios (ORs) were pooled using random-effects meta-analysis with restricted maximum likelihood and Hartung–Knapp adjustment; non-comparable metrics were synthesized separately. Results: Thirty studies were included; fifteen contributed to the primary OR meta-analysis. In the primary model, poorer oral status or function was associated with higher odds of adverse depressive outcomes (OR = 1.61, 95% CI: 1.31–1.99), although between-study heterogeneity was substantial (I2 = 88.1%). In the trim-and-fill sensitivity analysis, the pooled estimate decreased to OR = 1.29 (95% CI: 0.99–1.69; p = 0.0584) and no longer reached conventional statistical significance. The certainty of the primary evidence was very low. Conclusions: Poorer oral structural or functional status is associated with worse depressive outcomes in older adults, but the magnitude is heterogeneous and sensitive to small-study-effect assumptions. The evidence remains observational and of very low certainty and should be interpreted as hypothesis-generating rather than causal or treatment evidence. Full article
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