Advanced Melanoma: Navigating Resistance, Toxicities, and Emerging Therapies

A Special Issue of Clinics and Practice (ISSN 2039-7283).

Deadline for manuscript submissions: 31 August 2027 | Viewed by 32

Editors


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Guest Editor
1. Department of Hematology and Oncology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
2. University Hospitals Seidman Cancer Center, Cleveland, OH 44103, USA
3. Case Comprehensive Cancer Center, Cleveland, OH 44106, USA
Interests: checkpoint inhibitors; cell therapy; melanoma; T-cell receptor therapy; oncolytic virus; intratumoral therapy; interleukin; immune-related adverse effects; immunomodulation

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Guest Editor
Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90033, USA
Interests: skin cancer; melanoma; acral lentiginous melanoma; uveal melanoma; mucosal melanoma; squamous cell carcinoma
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Melanoma is the deadliest among all skin cancers. Fortunately, the introduction of immunotherapy has improved outcomes for patients with melanoma over the last decade. However, the treatment paradigm has evolved rapidly, creating controversy and unique opportunities in the treatment of patients with advanced melanoma. Patients with melanoma continue to face challenges in terms of determining the right fit for treatment, immunotherapy-related side effects, post-immunotherapy failure treatment choices, access to clinical trials, and social barriers to expert care, among others. This Special Issue aims to present and disseminate recent developments in the treatment of patients with localized and advanced melanoma. As treatment choices for patients with melanoma evolve, along with recent advances in relapse prediction models, treatment beyond anti-PD1 failure, and the introduction of new biologics for immunotherapy-related side effects, this Issue serves as a timely avenue for disseminating research in this area.

We welcome contributions to this Issue addressing recent developments in therapeutic options, management of immunotherapy-related adverse events, and barriers to accessing care for patients diagnosed with localized, advanced resectable, and metastatic melanoma. The topics of interest will include, but are not limited to:

  1. Treatment options for patients with melanoma with brain metastasis;
  2. Management of patients with anti-PD1 refractory melanoma;
  3. Utility of Liquid biopsy and circulating tumor DNA in the management of patients with advanced melanoma;
  4. Strategies to reduce the occurrence of melanoma/skin cancers.

Dr. Ankit Mangla
Dr. Gino K. In
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Clinics and Practice is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metastatic melanoma
  • brain metastasis
  • circulating tumor DNA
  • immunotherapy-related side effects
  • anti-PD1 refractory melanoma

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Published Papers

This special issue is now open for submission.
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