MicroRNA Microarrays
A special issue of BioTech (ISSN 2673-6284).
Deadline for manuscript submissions: closed (31 January 2013) | Viewed by 211
Special Issue Information
Dear Colleagues,
After the first microRNA was discovered in 1993, those 20-22nt size non-coding antisense inhibitory RNAs very quickly moved into spotlight as a new class of genes that is playing critical role in regulation of gene expression during development and normal functioning of cells and tissues in plants or animals. During last several years thousands of new micro-RNA molecules were discovered or predicted to be an essential regulatory genes in both normal and diseases states. Profiling for miRNAs expression and search for their mRNA targets are still very challenging tasks.
Microarray technology on other hand became a standard approach when there is a need for reliable screening technique applicable for multiple biological samples and particular for genomic materials. Thus the application of microarrays for microRNA studies became a useful tool in basic research and drug discovery.
In this issue we are inviting material about new developments and applications of microarray based technologies in field of microRNA expression profiling, in screening for targeted mRNAs, in discovery of new regulatory functions of those small noncoding genes. Information about new developments associated with annotations of miRNAs in databases and data analysis for miRNA microarrays is also critical in area of microarray technologies.
Dr. Veronica Soloveva
Guest Editor
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Keywords
- miRNA microarrays, microchips
- miRNA expression
- profiling
- targets of miRNA
- repression and induction by miRNA
- viral miRNA
- miRNA database
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