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Therapeutics, Volume 2, Issue 1

March 2025 - 5 articles

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Articles (5)

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Review

1 Citations

2,051 Views

16 Pages

How Natural Therapies Can Combat Neoplastic Disease by Targeting Key Survival Mechanisms and Signaling Pathways

Simge Karagil,
Aleksandra Szczesnowska,
Natalia Haddad,
Sara Magura Gamaethige,
Ellen Coakley,
Nabila Dawood,
Vernard J. Rama,
James Barker,
Moses K. Langat and
Huda Morgan
+ 2 authors

Therapeutics2025, 2(1), 5;https://doi.org/10.3390/therapeutics2010005

5 March 2025

Plant extracts are increasingly becoming an answer to expensive, high-dose, synthesized chemotherapy, with milder side effects and easier accessibility. Many botanical plants contain active ingredients, such as terpenoids and alkaloids, which may com...

Full Article

Communication

1 Citations

968 Views

9 Pages

Patient and Healthcare Provider Perceptions of Handgrip Strength in an Internal Medicine Resident Clinic

Michaela Mastrud,
Kirsten Juhl,
Lindsey Dahl,
Shabbir Haiderbhai,
Peyton Lahr,
Gunjan Manocha,
Abbigail Olson,
Jennifer Raum,
David Theige and
Ryan McGrath

Therapeutics2025, 2(1), 4;https://doi.org/10.3390/therapeutics2010004

5 March 2025

Background: Handgrip strength (HGS) is strongly recommended for use in clinical settings because it is a convenient assessment of muscle strength and a robust prognostic indicator of health. However, it may lack use in clinical settings, and may not...

Full Article

Review

2,080 Views

13 Pages

Examining Benefits and Limitations to Treatment Outcome Measurement Tools for Substance Use Disorder: A Scoping Review

Darian Peters,
Jacob Kalathoor,
Courtney Phillips,
Belma Andric and
Lea Sacca

Therapeutics2025, 2(1), 3;https://doi.org/10.3390/therapeutics2010003

25 February 2025

Background/Objectives: This scoping review aims to identify the diverse existing tools applicable for the measurement of SUD outcomes, examining and comparing their item characteristics, benefits, limitations, cost effectiveness, and overall utility....

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Article

1 Citations

3,981 Views

14 Pages

Effects of Daratumumab (Anti-CD38) Monoclonal Antibody Therapy on Flow Cytometry Analysis in Multiple Myeloma

Sharon Koorse Germans,
Christine Wamsley Kahlow,
Weina Chen and
Franklin Fuda

Therapeutics2025, 2(1), 2;https://doi.org/10.3390/therapeutics2010002

18 February 2025

Background: Plasma cell myeloma is an incurable malignancy of clonal plasma cells. Recent success in immunotherapeutic strategies has altered the landscape of myeloma treatment. Daratumumab is an anti-CD38 IgG kappa monoclonal antibody that has shown...

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Article

1,140 Views

12 Pages

A Broken Heart and Windy Nights: Single Center Results of Inpatient Sleep Studies and Interventions in Hospitalized Heart Failure Patients

Justin N. Durland,
Frank Hoyland,
John Elliott Epps,
Mathew J. Gregoski,
Jacqueline Angles and
Gregory R. Jackson

Therapeutics2025, 2(1), 1;https://doi.org/10.3390/therapeutics2010001

17 January 2025

Background: Past studies have found mixed benefits to treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) in heart failure (HF) patients. Here we evaluate the effect of OSA treatment in symptomatic HF patients w...

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