Does Incision Type Impact Culture Positivity in Implant-Based Reconstruction Complications for Breast Cancer and Breast Cancer Prophylaxis?
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Culture-Positive vs. Culture-Negative IBR Complications
3.2. Cultured Organisms in Culture-Positive IBR Complications
3.3. Antibiotic Use for IBR Complications
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| IBR | Implant-based reconstruction |
| SSI | Surgical site infection |
| BMI | Body mass index |
| NSM | Nipple-sparing mastectomy |
| IMF | Inframammary fold |
| PO | Per oral |
| IV | Intravenous |
References
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| Culture-Positive IBR Complication (N = 80) | Culture-Negative IBR Complication (N = 103) | p-Value | |
|---|---|---|---|
| Age at index operation (years) | |||
| Mean (SD) | 55.36 (11.54) | 55.9 (10.43) | 0.63 1 |
| Median (range) | 54.48 (31.17–81.89) | 55.1 (32.28–75.97) | |
| BMI | 0.62 1 | ||
| Mean (SD) | 28.72 (5.76) | 29.31 (6.21) | |
| Median (range) | 27.36 (19.19–41.67) | 28.90 (16.32–45.7) | |
| Diabetes | 10 (12.5%) | 12 (11.65%) | 0.86 2 |
| Prior radiation | 22 (27.5%) | 38 (36.89%) | 0.18 2 |
| Prior chemotherapy | 32 (40%) | 49 (47.57%) | 0.31 2 |
| Incision types | 0.56 2 | ||
| Ellipse | 64 (80%) | 74 (71.84%) | |
| IMF | 6 (7.5%) | 13 (12.62%) | |
| Lateral | 5 (6.25%) | 9 (8.74%) | |
| Periareolar | 5 (6.25%) | 5 (4.85%) | |
| Wise | 0 | 2 (1.94%) | |
| NSM | 13 (16.3%) | 25 (24.2%) | 0.18 2 |
| Implant type threatened | 0.47 2 | ||
| Tissue expander | 67 (83.8%) | 82 (79.6%) | |
| Direct to implant | 13 (16.2%) | 21 (20.4%) | |
| Implant removal | 77 (96.2%) | 89 (86.4%) |
| Infectious Organism | N (%) |
|---|---|
| Methicillin-sensitive Staphylococcus aureus | 19/80 (23.8) |
| Pseudomonas aeruginosa | 18/80 (22.5) |
| Coagulase-negative Staphylococcus | 14/80 (17.5) |
| Other monomicrobial | 22/80 (27.5) |
| Polymicrobial | 8/80 (10) |
| Organism | Ellipse (N) | IMF (N) | Lateral (N) | Periareolar (N) |
|---|---|---|---|---|
| Actinomyces neuii | 1 | 0 | 0 | 0 |
| Bacteroides fragilis | 1 | 0 | 0 | 0 |
| Candida | 0 | 1 | 0 | 0 |
| Coagulase-negative Staphylococcus | 13 | 0 | 1 | 1 |
| Enterobacter cloacae | 0 | 0 | 1 | 1 |
| Escherichia coli | 2 | 0 | 0 | 0 |
| Finegoldia magna | 1 | 0 | 0 | 0 |
| Group B Streptococcus | 0 | 1 | 0 | 0 |
| Klebsiella | 1 | 0 | 0 | 0 |
| MRSA | 3 | 0 | 1 | 0 |
| MSSA | 18 | 0 | 0 | 0 |
| Proteus mirabilis | 3 | 1 | 0 | 0 |
| Pseudomonas aeruginosa | 12 | 3 | 2 | 1 |
| Serratia marcescens | 1 | 0 | 0 | 0 |
| Streptococcus mitis | 1 | 0 | 0 | 0 |
| Streptococcus viridans | 1 | 0 | 0 | 0 |
| Polymicrobial | 6 | 0 | 0 | 2 |
| Culture-Positive IBR Complication (N = 80) | Culture-Negative IBR Complication (N = 103) | p-Value | |
|---|---|---|---|
| Administration route | 0.0005 1 | ||
| PO | 59 (73.8%) | 49 (47.6%) | |
| IV | 4 (5%) | 3 (2.9%) | |
| PO and IV | 2 (2.5%) | 1 (1.0%) | |
| None | 15 (18.8%) | 50 (48.5%) | |
| Administration duration (days) | 0.039 2 | ||
| Mean (SD) | 5.78 (5.22) | 8.52 (8.35) | |
| Median (range) | 4 (1–26) | 7 (1–49) |
| Ellipse N = 138 | IMF N = 19 | Lateral N = 14 | Periareolar N = 10 | p-Value | |
|---|---|---|---|---|---|
| Administration route | |||||
| PO | 83 | 15 | 8 | 2 (10 days) | |
| IV | 4 | 1 | 2 | 0 | |
| PO and IV | 1 | 0 | 1 | 1 (3 days) | |
| None | 50 | 3 | 3 | 7 | |
| Administration duration (days) | 0.77 1 | ||||
| Mean (SD) | 6.85 (6.32) | 9.5 (12.3) | 8.36 (7.51) | ||
| Median (range) | 5.5 (1–30) | 6 (1–49) | 7 (1–25) |
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Im, K.; Yoshinaga, S.; Jiangliu, Y.; Chu, M.W.; Carre, A.L.; Leung, A.M. Does Incision Type Impact Culture Positivity in Implant-Based Reconstruction Complications for Breast Cancer and Breast Cancer Prophylaxis? Complications 2026, 3, 7. https://doi.org/10.3390/complications3010007
Im K, Yoshinaga S, Jiangliu Y, Chu MW, Carre AL, Leung AM. Does Incision Type Impact Culture Positivity in Implant-Based Reconstruction Complications for Breast Cancer and Breast Cancer Prophylaxis? Complications. 2026; 3(1):7. https://doi.org/10.3390/complications3010007
Chicago/Turabian StyleIm, Kyuseok, Steven Yoshinaga, Yilan Jiangliu, Michael W. Chu, Antoine L. Carre, and Anna M. Leung. 2026. "Does Incision Type Impact Culture Positivity in Implant-Based Reconstruction Complications for Breast Cancer and Breast Cancer Prophylaxis?" Complications 3, no. 1: 7. https://doi.org/10.3390/complications3010007
APA StyleIm, K., Yoshinaga, S., Jiangliu, Y., Chu, M. W., Carre, A. L., & Leung, A. M. (2026). Does Incision Type Impact Culture Positivity in Implant-Based Reconstruction Complications for Breast Cancer and Breast Cancer Prophylaxis? Complications, 3(1), 7. https://doi.org/10.3390/complications3010007

