An Activatable Nanoscintillator Probe for Detecting Telomerase Activity and Screening Inhibitors In Vivo
Abstract
:1. Introduction
2. Materials and Methods
3. Results and Discussion
3.1. Synthesis and Characterization of the Probe
3.2. Telomerase Detection In Vitro
3.3. Analysis of Intracellular Telomerase Activity
3.4. Screening Telomerase Inhibitors in Living Cells
3.5. In Vivo Imaging of Telomerase Activity
3.6. Telomerase Inhibitor Screening In Vivo
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Chen, B.; Dai, J.; Song, S.; Tang, X.; Guo, Y.; Wu, T.; Wu, M.; Hao, C.; Cheng, X.; Lin, X.; et al. An Activatable Nanoscintillator Probe for Detecting Telomerase Activity and Screening Inhibitors In Vivo. Targets 2023, 1, 34-47. https://doi.org/10.3390/targets1010004
Chen B, Dai J, Song S, Tang X, Guo Y, Wu T, Wu M, Hao C, Cheng X, Lin X, et al. An Activatable Nanoscintillator Probe for Detecting Telomerase Activity and Screening Inhibitors In Vivo. Targets. 2023; 1(1):34-47. https://doi.org/10.3390/targets1010004
Chicago/Turabian StyleChen, Baoliu, Junduan Dai, Sijie Song, Xianzhe Tang, Yuheng Guo, Ting Wu, Mengnan Wu, Chaojie Hao, Xiaofeng Cheng, Xucong Lin, and et al. 2023. "An Activatable Nanoscintillator Probe for Detecting Telomerase Activity and Screening Inhibitors In Vivo" Targets 1, no. 1: 34-47. https://doi.org/10.3390/targets1010004