Hydrobiological Aspects of Saturated, Methyl-Branched, and Cyclic Fatty Acids Derived from Aquatic Ecosystems: Origin, Distribution, and Biological Activity
Abstract
:1. Introduction
2. Acyclic Aliphatic Fatty (Carboxylic) Acids
3. Comparison of Biological Activities of Natural Saturated Fatty Acids
4. Conclusions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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No. | Predicted Biological Activity, Pa * | Reported Activity | Ref. |
---|---|---|---|
1 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) Atherosclerosis treatment (0.634), Antiprotozoal (Coccidial) (0.514) | Antibacterial Anti-fungal Anti-protozoan Antiviral | [132] |
2 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) Atherosclerosis treatment (0.634), Antiprotozoal (Coccidial) (0.514) | Antibacterial Anti-protozoan Anti-fungal Antiviral | [132] |
3 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) | Antibacterial Anti-fungal Anti-protozoan | [132] |
4 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) | Antibacterial Antiviral | [132] |
5 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) | Antibacterial Anti-fungal | [132] |
6 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) | Antibacterial | [132] |
7 | Preneoplastic conditions treatment (0.836), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) | Antibacterial Anticancer | [132,133] |
8 | Lipid metabolism regulator (0.860), Antiviral (Arbovirus) (0.833) Anti-inflammatory (0.709), Antiviral (Picornavirus) (0.706) Anti-hypercholesterolemic (0.646), Antibacterial (0.638) | Antibacterial Anti-breast cancer | [132,134] |
9 | Lipid metabolism regulator (0.913), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Antiviral (Arbovirus) (0.705), Antiviral (Picornavirus) (0.617) | Antibacterial Antiviral Hemolytic | [132] |
10 | Lipid metabolism regulator (0.913), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Antiviral (Arbovirus) (0.705), Antiviral (Picornavirus) (0.617) | No experimental data | |
11 | Lipid metabolism regulator (0.913), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Antiviral (Arbovirus) (0.705), Antiviral (Picornavirus) (0.617) | No experimental data | |
12 | Lipid metabolism regulator (0.913), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Antiviral (Arbovirus) (0.705), Antiviral (Picornavirus) (0.617) | No experimental data | |
13 | Lipid metabolism regulator (0.817), Hypolipemic (0.784) Antiviral (Arbovirus) (0.768), Antineurotic (0.752) Antiviral (Picornavirus) (0.683), Antifungal (0.567) | No experimental data |
No. | Predicted Biological Activity, Pa * | Reported Activity | Ref. |
---|---|---|---|
14 | Sclerosant (0.878), Anesthetic general (0.849), Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805) Acute neurologic disorders treatment (0.723), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | No experimental data | |
15 | Sclerosant (0.878), Anesthetic general (0.849), Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805) Acute neurologic disorders treatment (0.723), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | No experimental data | |
16 | Sclerosant (0.878), Anesthetic general (0.849), Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805) Acute neurologic disorders treatment (0.723), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134,135] |
17 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134,135] |
18 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134] |
19 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134,135] |
20 | Lipid metabolism regulator (0.810), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | ||
21 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134,135] |
22 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134] |
23 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134] |
24 | Lipid metabolism regulator (0.810), Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649) | Anti-breast cancer | [134] |
25 | Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649), Antimutagenic (0.532) | No experimental data | |
26 | Preneoplastic conditions treatment (0.805), Antiviral (Arbovirus) (0.716), Antiviral (Picornavirus) (0.649), Antimutagenic (0.532) | No experimental data |
No. | Predicted Biological Activity, Pa * |
---|---|
27 | Anti-hypercholesterolemic (0.801), Preneoplastic conditions treatment (0.793) Hypolipemic (0.768), Acute neurologic disorders treatment (0.718) Atherosclerosis treatment (0.679), Antineoplastic (0.566), Antiparasitic (0.526) |
28 | Anti-hypercholesterolemic (0.801), Preneoplastic conditions treatment (0.793) Hypolipemic (0.768), Acute neurologic disorders treatment (0.718) Atherosclerosis treatment (0.679), Antineoplastic (0.566), Antiparasitic (0.526) |
29 | Anti-hypercholesterolemic (0.801), Preneoplastic conditions treatment (0.793) Hypolipemic (0.768), Acute neurologic disorders treatment (0.718) Atherosclerosis treatment (0.679), Antineoplastic (0.566), Antiparasitic (0.526) |
30 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801); Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
31 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
32 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
33 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
34 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718); Anticonvulsant (0.717) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
35 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
36 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
37 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
38 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
39 | Lipid metabolism regulator (0.913), Anti-hypercholesterolemic (0.801), Hypolipemic (0.768) Acute neurologic disorders treatment (0.718), Anticonvulsant (0.717) Atherosclerosis treatment (0.679), Antifungal (0.592), Antiparasitic (0.526) |
No. | Predicted Biological Activity, Pa * |
---|---|
40 | Lipid metabolism regulator (0.905), Anti-hypercholesterolemic (0.789), Hypolipemic (0.757) |
41 | Lipid metabolism regulator (0.817), Anti-hypercholesterolemic (0.674) Atherosclerosis treatment (0.643) |
42 | Lipid metabolism regulator (0.905), Anti-hypercholesterolemic (0.789) Atherosclerosis treatment (0.682) |
43 | Lipid metabolism regulator (0.853), Hypolipemic (0.767) Anti-hypercholesterolemic (0.699), Atherosclerosis treatment (0.694) |
44 | Hypolipemic (0.863), Lipid metabolism regulator (0.803) Atherosclerosis treatment (0.655), Anti-hypercholesterolemic (0.610) |
45 | Lipid metabolism regulator (0.877), Hypolipemic (0.809) Atherosclerosis treatment (0.701), Anti-hypercholesterolemic (0.656) |
46 | Lipid metabolism regulator (0.877), Hypolipemic (0.809) Atherosclerosis treatment (0.701), Anti-hypercholesterolemic (0.656) |
47 | Lipid metabolism regulator (0.877); Hypolipemic (0.809) Atherosclerosis treatment (0.701), Anti-hypercholesterolemic (0.656) |
48 | Lipid metabolism regulator (0.865), Hypolipemic (0.781) Anti-hypercholesterolemic (0.721), Atherosclerosis treatment (0.659) |
49 | Lipid metabolism regulator (0.854), Anti-hypercholesterolemic (0.766) Hypolipemic (0.740), Atherosclerosis treatment (0.685) |
50 | Lipid metabolism regulator (0.860), Anti-hypercholesterolemic (0.790) Hypolipemic (0.769), Atherosclerosis treatment (0.692) |
51 | Hypolipemic (0.833), Acute neurologic disorders treatment (0.830) Lipid metabolism regulator (0.771), Anti-hypercholesterolemic (0.701) Atherosclerosis treatment (0.698), Anti-inflammatory (0.662) |
52 | Lipid metabolism regulator (0.790) Anti-hypercholesterolemic (0.757), Hypolipemic (0.677) |
53 | Lipid metabolism regulator (0.854), Anesthetic general (0.793) Anti-hypercholesterolemic (0.766), Hypolipemic (0.740) |
54 | Hypolipemic (0.833), Acute neurologic disorders treatment (0.830) Lipid metabolism regulator (0.771), Neuroprotector (0.676) |
55 | Mucositis treatment (0.842), Fibrinolytic (0.821); Antithrombotic (0.635), Antimutagenic (0.566) |
56 | Anti-eczematic (0.893), Mucositis treatment (0.842); Fibrinolytic (0.821), Anti-inflammatory (0.704) |
57 | Anti-eczematic (0.893), Mucositis treatment (0.842); Fibrinolytic (0.821), Anti-inflammatory (0.704) |
58 | Fibrinolytic (0.915), Cardiovascular analeptic (0.715), Antithrombotic (0.688) Anti-ischemic, cerebral (0.655), Platelet antagonist (0.581), Anticoagulant (0.515) |
59 | Fibrinolytic (0.915), Cardiovascular analeptic (0.715), Antithrombotic (0.688) Anti-ischemic, cerebral (0.655), Platelet antagonist (0.581), Anticoagulant (0.515) |
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Dembitsky, V.M. Hydrobiological Aspects of Saturated, Methyl-Branched, and Cyclic Fatty Acids Derived from Aquatic Ecosystems: Origin, Distribution, and Biological Activity. Hydrobiology 2022, 1, 89-110. https://doi.org/10.3390/hydrobiology1010007
Dembitsky VM. Hydrobiological Aspects of Saturated, Methyl-Branched, and Cyclic Fatty Acids Derived from Aquatic Ecosystems: Origin, Distribution, and Biological Activity. Hydrobiology. 2022; 1(1):89-110. https://doi.org/10.3390/hydrobiology1010007
Chicago/Turabian StyleDembitsky, Valery M. 2022. "Hydrobiological Aspects of Saturated, Methyl-Branched, and Cyclic Fatty Acids Derived from Aquatic Ecosystems: Origin, Distribution, and Biological Activity" Hydrobiology 1, no. 1: 89-110. https://doi.org/10.3390/hydrobiology1010007