AI-Assisted Precision Psychotherapy: Toward a Process-Based Framework of Therapeutic Interaction
Abstract
1. Introduction
1.1. Variability in Psychotherapy Outcomes
1.2. Emergence of Precision Medicine, Precision Psychiatry, and Precision Psychotherapy
1.3. The Gap in Psychotherapy
1.4. Aim of the Article
2. The Concept of Precision Psychotherapy
Conceptual Definitions
3. Current Approaches to Precision Psychotherapy
3.1. Predictive Modeling and Machine Learning
3.2. Mechanisms of Change Approaches
3.3. Enhanced Psychotherapy and Digital Augmentation
3.4. The Process Gap in Precision Psychotherapy
3.5. AI-Based Analysis of Psychotherapy Process
4. A Dimensional Model of Therapeutic Interaction
4.1. The Dimensional Model of Mental Activity
4.2. Implications for AI-Based Process Analysis
4.3. Clinical Example: Dimensional Mismatch and Premature Interpretation in Psychotherapeutic Dialogue
5. Clinical and Research Implications
5.1. Implications for Therapist Training
5.2. Implications for Clinical Trials
5.3. Ethical Considerations
6. Limitations
7. Conclusions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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| Utterance | Speaker | Utterance | Dimension | Remark |
|---|---|---|---|---|
| 1 | Patient | I’m not sure how to say this… there’s just this tight feeling in my chest when I think about going back home. | Experience | |
| 2 | Therapist | Stay with that for a moment. What does that feeling seem like from the inside? | None | (Question/facilitative intervention) |
| 3 | Patient | It’s strange… almost like something is pressing down. | Experience | |
| 4 | Therapist | Pressing down? | None | (Question/facilitative intervention) |
| 5 | Patient | Yes… like I can’t quite breathe fully. | Experience | |
| 6 | Therapist | What happens as you notice it right now? | None | (Question/facilitative intervention) |
| 7 | Patient | It gets a bit stronger when I talk about it. | Experience | |
| 8 | Therapist | Stronger in your chest? | None | (Question/facilitative intervention) |
| 9 | Patient | Yes… it feels heavy… maybe a little sad. | Experience | |
| 10 | Therapist | Sad. | Experience | |
| 11 | Patient | Yes… but it’s not exactly sadness… it’s more like something is about to come up. | Experience | |
| 12 | Therapist | Perhaps you are interpreting your reaction in a way that relates to unresolved issues with your father. | Thought | |
| 13 | Patient | …No, that doesn’t feel right. | Experience | (Patient’s retraction) |
| 14 | Therapist | What doesn’t feel right about it? | None | (Question/facilitative intervention) |
| 15 | Patient | I don’t know… the feeling I was talking about is gone now. | Experience | (Patient’s retraction) |
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Mendlovic, S. AI-Assisted Precision Psychotherapy: Toward a Process-Based Framework of Therapeutic Interaction. Psychiatry Int. 2026, 7, 124. https://doi.org/10.3390/psychiatryint7030124
Mendlovic S. AI-Assisted Precision Psychotherapy: Toward a Process-Based Framework of Therapeutic Interaction. Psychiatry International. 2026; 7(3):124. https://doi.org/10.3390/psychiatryint7030124
Chicago/Turabian StyleMendlovic, Shlomo. 2026. "AI-Assisted Precision Psychotherapy: Toward a Process-Based Framework of Therapeutic Interaction" Psychiatry International 7, no. 3: 124. https://doi.org/10.3390/psychiatryint7030124
APA StyleMendlovic, S. (2026). AI-Assisted Precision Psychotherapy: Toward a Process-Based Framework of Therapeutic Interaction. Psychiatry International, 7(3), 124. https://doi.org/10.3390/psychiatryint7030124

