Knowledge and Practices in Diabetic Foot Ulcer Prevention Among Patients with Diabetes Mellitus in Gauteng, South Africa
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Setting
2.2. Sample
DEFF = design effect
2.3. Instrument
2.4. Pilot Study
2.5. Ethical Consideration
2.6. Statistical Analyses
3. Results
Toenail Cutting Practices: Participant Preferences
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| DFI | Diabetic foot infection | 
| DFU | Diabetic foot ulcer | 
| DM | Diabetes mellitus | 
| IDF | International Diabetes Federation | 
| IWGDF | International Working Group on Diabetic Foot | 
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| Population size (for finite population correction factor or fpc) (N): | 1,000,000 | 
| Hypothesized % frequency of outcome factor in the population (p): | 15% +/− 5 | 
| Confidence limits as % of 100(absolute +/− %) (d): | 5% | 
| Design effect (for cluster surveys-DEFF): | 1 | 
| Sample Size (n) for Various Confidence Levels | |
| Confidence Level (%) | Sample Size | 
| 95% | 196 | 
| 80% | 84 | 
| 90% | 138 | 
| 97% | 241 | 
| 99% | 339 | 
| 99.9% | 552 | 
| 99.99% | 772 | 
| Variable | Result | 
|---|---|
| Sex | |
| Male | 74 (30.2%) | 
| Female | 169 (69%) | 
| Not specified | 2 (0.8%) | 
| Level of Education | |
| Primary | 149 (60.8%) | 
| Graduate | 67 (27.3%) | 
| Postgraduate | 18 (7.3%) | 
| Uneducated | 11 (4.5%) | 
| Level of Care of Facility | |
| Primary | 92 (37.6%) | 
| Secondary | 40 (16.3%) | 
| Tertiary | 113 (46.1%) | 
| Marital Status | |
| Divorced | 21 (8.6%) | 
| Married | 101 (41.2%) | 
| Single | 111 (45.3%) | 
| Widowed | 12 (4.9%) | 
| Type of DM | |
| Type 1 | 55 (22.4%) | 
| Type 2 | 190 (77.6%) | 
| Duration of DM | |
| <10 years | 129 (52.7%) | 
| 10–20 years | 73 (29.8%) | 
| 21–30 years | 31 (12.7%) | 
| >30 years | 12 (4.9%) | 
| Treatment of DM | |
| Insulin | 70 (28.6%) | 
| Oral and insulin | 92 (37.6%) | 
| Oral | 83 (33.9%) | 
| Education received from healthcare workers | |
| No | 136 (55.5%) | 
| Yes | 109 (44.5%) | 
| Current foot problems | |
| Amputation | 8 (3.3%) | 
| Callosities | 36 (14.7%) | 
| Circulation problems | 28 (11.4%) | 
| Nail pathologies | 36 (14.7%) | 
| Parasthesia | 95 (38.8%) | 
| Ulcer | 8 (3.3%) | 
| Multiple | 33 (14%) | 
| Smoker | |
| No | 214 (87.3%) | 
| Yes | 31 (12.7%) | 
| Variable | Results | 
|---|---|
| Participants who correctly agreed | |
| Daily washing of feet | 98% | 
| Always drying the feet after washing | 94% | 
| Application of lotion or moisturizer on the feet after washing | 88% | 
| Exercising is good for the feet | 88% | 
| Going to a clinic if experiencing non-healing | 84% | 
| Checking water temperature first before washing the feet | 81% | 
| Routinely checking the shoes before putting them on | 81% | 
| Treatment of an open wound with saline or an antiseptic | 67% | 
| Perform daily foot examination | 59% | 
| Going to a clinic immediately upon noticing a wound | 59% | 
| Participants who correctly disagreed | |
| Utilization of corn plasters or removers | 86% | 
| Using a heater or fire to warm the feet | 79% | 
| Immediately opening foot blister(s) upon noticing | 78% | 
| Warming the feet with hot water bottle in winter | 72% | 
| Walking barefoot | 71% | 
| Cutting calluses self | 65% | 
| Wearing shoes without socks | 61% | 
| Wearing slippers outdoor | 46% | 
| Putting lotion or moisturizer between toes to keep the area moist | 45% | 
| Variable | UOR | p-Value | AOR | p-Value | 
|---|---|---|---|---|
| Sex | ||||
| Male | 1.25 (0.72–2.16) | 0.4270 | ||
| Female | 1 (base) | |||
| Education | ||||
| Primary | 1.23 (0.69–2.19) | 0.084 | 1.16 (0.58–2.33) | 0.151 | 
| Graduate | 1 (base) | 1 (base) | ||
| Postgraduate | 1.72 (0.59–4.97) | 2.67 (0.78–9.09) | ||
| Uneducated | 0.24 (0.05–1.21) | 0.26 (0.04–1.63) | ||
| Level of care | ||||
| Primary | 0.74 (0.43–1.29) | 0.4737 | ||
| Secondary | 1.08 (0.52–2.23) | |||
| Tertiary | 1 (base) | |||
| Marital status | ||||
| Divorced | 1.34 (0.53–3.42) | 0.3525 | ||
| Married | 1.46 (0.84–2.51) | |||
| Single | 1 (base) | |||
| Widowed | 2.44 (0.69–8.58) | |||
| Type of DM | ||||
| I | 0.43 (0.23–0.79) | 0.0008 | 0.8 (0.32–2.01) | 0.637 | 
| II | 1 (base) | 1 (base) | ||
| Duration of DM | ||||
| <10 | 1 (base) | 0.009 | 1 (base) | 0.049 | 
| 10–20 | 0.97 (0.55–1.73) | 0.95 (0.47–1.93) | ||
| 21–30 | 3.2 (1.34–7.69) | 2.78 (1.01–7.68) | ||
| >30 | 1.11 (0.34–3.64) | 1.74 (0.41–7.36) | ||
| Treatment of DM | ||||
| Insulin | 0.38 (0.19–0.72) | 0.003 | 0.4 (0.17–0.94) | 0.035 | 
| Oral and insulin | 1 (base) | 1 (base) | ||
| Oral | 1.11 (0.61–2.02) | 1.08 (0.53–2.21) | ||
| Education in healthcare | ||||
| No | 1 (base) | <0.00001 | 1 (base) | 0.001 | 
| Yes | 2.93 (1.73–4.94) | 2.78 (1.55–4.98) | ||
| Present foot problems | ||||
| Amputation | 0.17 (0.02–1.40) | 0.03 | 0.2 (0.02–1.85) | 0.433 | 
| Callosities | 1.30 (0.60–2.79) | 0.93 (0.38–2.24) | ||
| Circulation problems | 0.75 (0.32–1.77) | 0.62 (0.23–1.64) | ||
| Nail pathologies | 2.41 (1.09–5.36) | 1.43 (0.59–3.50) | ||
| Parasthesia | 1 (base) | 1 (base) | ||
| Ulcer | 0.70 (0.16–3.08) | 0.58 (0.12–2.92) | ||
| Multiple | 2.03 (0.89–4.59) | 1.05 (0.41–2.69) | ||
| Age | 1.02 (1.007–1.04) | 0.004 | 1.0006 (0.98–1.02) | 0.958 | 
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Mukheli, T.; Mokoena, T.P.; Kagodora, S.B.; Luvhengo, T.E. Knowledge and Practices in Diabetic Foot Ulcer Prevention Among Patients with Diabetes Mellitus in Gauteng, South Africa. Diabetology 2025, 6, 125. https://doi.org/10.3390/diabetology6110125
Mukheli T, Mokoena TP, Kagodora SB, Luvhengo TE. Knowledge and Practices in Diabetic Foot Ulcer Prevention Among Patients with Diabetes Mellitus in Gauteng, South Africa. Diabetology. 2025; 6(11):125. https://doi.org/10.3390/diabetology6110125
Chicago/Turabian StyleMukheli, Tshifhiwa, Tshepo P. Mokoena, Shingirai B. Kagodora, and Thifhelimbilu E. Luvhengo. 2025. "Knowledge and Practices in Diabetic Foot Ulcer Prevention Among Patients with Diabetes Mellitus in Gauteng, South Africa" Diabetology 6, no. 11: 125. https://doi.org/10.3390/diabetology6110125
APA StyleMukheli, T., Mokoena, T. P., Kagodora, S. B., & Luvhengo, T. E. (2025). Knowledge and Practices in Diabetic Foot Ulcer Prevention Among Patients with Diabetes Mellitus in Gauteng, South Africa. Diabetology, 6(11), 125. https://doi.org/10.3390/diabetology6110125
        
