From Imaging to Instrument: A CT-Based Classification of the Nasofrontal Beak and Frontal Ostium Clearance with Prospective Surgical Correlation
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Participants
2.2. CT Acquisition and Measurement Protocol
2.3. Method Equivalence Analysis
2.4. CT Classification Development
2.5. Surgical Intervention
2.6. Interobserver Agreement and Statistical Analysis
3. Results
3.1. Findings from Phase 1
3.2. Findings from Phase 2
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| CI | Confidence Interval |
| CSF | Cerebrospinal Fluid |
| CT | Computed Tomography |
| DICOM | Digital Imaging and Communications in Medicine |
| ESS | Endoscopic Sinus Surgery |
| FO | Frontal Ostium |
| FOC | Frontal Ostium Clearance |
| FOG | Frontal Ostium Grade |
| ICC | Intraclass Correlation Coefficient |
| IFAC | International Frontal Sinus Anatomy Classification |
| IQR | Interquartile Range |
| MPR | Multiplanar Reconstruction |
| NFB | Nasofrontal Beak |
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| Nasofrontal Beak Anteroposterior Length | Frontal Ostium Clearance Length | ||
|---|---|---|---|
| Class A | ≤6 mm | Class A | ≥12 mm |
| Class B | 6–12 mm | Class B | 6–12 mm |
| Class C | ≥12 mm | Class C | ≤6 mm |
| Surgical Techniques (common pairs §) | |||
| Class A NFB, Class A FOC: The NFB was left unaltered; the operation continued based on pathology. | |||
| Class B NFB, Class B FOC: The posterior two-thirds of the NFB was shortened using a frontal sinus punch (70°, small). | |||
| Class C NFB, Class C FOC: A straight or curved (45°) drill was used to remove the posterior two-thirds and part of the anterior one-third of the NFB. | |||
| Variables | Phase 1—n (%) | Phase 2—n (%) | Total |
|---|---|---|---|
| Sex | |||
| Male | 828 (59.9%) | 57 (57.0%) | 885 (59.7%) |
| Female | 555 (40.1%) | 43 (43.0%) | 598 (40.3%) |
| Frontal Sinus Side | |||
| Right | 1305 (50.3%) | 98 (51.3%) | 1403 (50.4%) |
| Left | 1290 (49.7%) | 93 (48.7%) | 1383 (49.6%) |
| NFB Length Classes | |||
| Class A (≤6 mm) | 123 (4.7%) | 10 (5.2%) | 133 (4.8%) |
| Class B (6–12 mm) | 2100 (80.9%) | 146 (76.4%) | 2246 (80.6%) |
| Class C (≥12 mm) | 372 (14.3%) | 35 (18.4%) | 407 (14.6%) |
| FOC Length Classes | |||
| Class A (≥12 mm) | 198 (7.6%) | 23 (12.0%) | 221 (7.9%) |
| Class B (6–12 mm) | 1182 (45.5%) | 68 (35.6%) | 1250 (44.9%) |
| Class C (≤6 mm) | 1215 (46.8%) | 100 (52.4%) | 1315 (47.2%) |
| Male | Female | p-Value | ||
|---|---|---|---|---|
| NFB Classification | Class A | 63 (51.2%) | 60 (48.8%) | <0.001 |
| Class B | 1222 (58.2%) | 878 (41.8%) | ||
| Class C | 273 (73.4%) | 99 (26.6%) | ||
| FOC Classification | Class A | 100 (50.5%) | 98 (49.5%) | 0.017 |
| Class B | 717 (60.7%) | 465 (39.3%) | ||
| Class C | 741 (61.0%) | 474 (39.0%) |
| Surgical Class A | Surgical Class B | p-Value | ||
|---|---|---|---|---|
| CT Classification | Class A | 10 (100%) | 0 (0%) | <0.001 |
| Class B | 49 (33.6%) | 97 (66.4%) | ||
| Class C | 0 (0.0%) | 12 (34.3%) * |
| Surgical Class A | Surgical Class B | p-Value | ||
|---|---|---|---|---|
| CT Classification | Class A | 85 (85%) | 15 (15%) | <0.001 |
| Class B | 39 (57.4%) | 25 (36.8%) | ||
| Class C | 3 (13.0%) | 13 (56.5%) |
| CT Class | Sensitivity | Specificity | PPV | NPV | n (CT) |
|---|---|---|---|---|---|
| Class A (≤6 mm) | 100.0% | 72.9% | 16.9% | 100.0% | 10 |
| Class B (6–12 mm) | 66.4% | 73.3% | 89.0% | 40.2% | 146 |
| Class C (≥12 mm) | 65.7% | 100.0% | 100.0% | 92.9% | 35 |
| CT Class | Sensitivity | Specificity | PPV | NPV | n (CT) |
|---|---|---|---|---|---|
| Class A (≥12 mm) | 30.4% | 97.6% | 63.6% | 91.1% | 23 |
| Class B (6–12 mm) | 36.8% | 77.2% | 47.2% | 68.8% | 68 |
| Class C (≤6 mm) | 85.0% | 53.8% | 66.9% | 76.6% | 100 |
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Omer, G.L.; Ali, S.S.; Turri-Zanoni, M.; Battaglia, P.; Dallan, I.; Gravina, A.; De Donato, G.; Castelnuovo, P.; Casiano, R.R.; Di Girolamo, S. From Imaging to Instrument: A CT-Based Classification of the Nasofrontal Beak and Frontal Ostium Clearance with Prospective Surgical Correlation. Surgeries 2026, 7, 86. https://doi.org/10.3390/surgeries7030086
Omer GL, Ali SS, Turri-Zanoni M, Battaglia P, Dallan I, Gravina A, De Donato G, Castelnuovo P, Casiano RR, Di Girolamo S. From Imaging to Instrument: A CT-Based Classification of the Nasofrontal Beak and Frontal Ostium Clearance with Prospective Surgical Correlation. Surgeries. 2026; 7(3):86. https://doi.org/10.3390/surgeries7030086
Chicago/Turabian StyleOmer, Goran Latif, Sahand Soran Ali, Mario Turri-Zanoni, Paolo Battaglia, Iacopo Dallan, Andrea Gravina, Giuseppe De Donato, Paolo Castelnuovo, Roy R. Casiano, and Stefano Di Girolamo. 2026. "From Imaging to Instrument: A CT-Based Classification of the Nasofrontal Beak and Frontal Ostium Clearance with Prospective Surgical Correlation" Surgeries 7, no. 3: 86. https://doi.org/10.3390/surgeries7030086
APA StyleOmer, G. L., Ali, S. S., Turri-Zanoni, M., Battaglia, P., Dallan, I., Gravina, A., De Donato, G., Castelnuovo, P., Casiano, R. R., & Di Girolamo, S. (2026). From Imaging to Instrument: A CT-Based Classification of the Nasofrontal Beak and Frontal Ostium Clearance with Prospective Surgical Correlation. Surgeries, 7(3), 86. https://doi.org/10.3390/surgeries7030086

