Next Article in Journal
Complementary Photothermal Heating Effects Observed between Gold Nanorods and Conjugated Infrared-Absorbing Dye Molecules
Next Article in Special Issue
Synthesis and Characterization of Various Bimetallic Nanoparticles and Their Application
Previous Article in Journal
Biogenic Silver Nanoparticles Processed Twice Using 8M Urea Exhibit Superior Antibacterial and Antifungal Activity to Commercial Chemically Synthesized Counterparts
Previous Article in Special Issue
Zeolites as Carriers of Nano-Fertilizers: From Structures and Principles to Prospects and Challenges
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Applied Nano
Volume 3
Issue 4
10.3390/applnano3040015
applnano-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Emerging Trends in Curcumin Embedded Electrospun Nanofibers for Impaired Diabetic Wound Healing

by
Ganesan Padmini Tamilarasi
1,
Manikandan Krishnan
1,*,
Govindaraj Sabarees
2,
Siddan Gouthaman
3,
Veerachamy Alagarsamy
4,* and
Viswas Raja Solomon
4,*
1
Department of Pharmaceutical Analysis, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India
2
Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India
3
Organic Material Laboratory, Department of Chemistry, Indian Institute of Technology, Roorkee 247667, India
4
Medicinal Chemistry Research Laboratory, MNR College of Pharmacy, Greater Hyderabad, Sangareddy 502294, India
*
Authors to whom correspondence should be addressed.
Appl. Nano 2022, 3(4), 202-232; https://doi.org/10.3390/applnano3040015
Submission received: 15 October 2022 / Revised: 11 November 2022 / Accepted: 15 November 2022 / Published: 17 November 2022
(This article belongs to the Collection Review Papers for Applied Nano Science and Technology)
Browse Figures
Review Reports Versions Notes

Abstract

Chronic wounds impose a significant burden on individuals and healthcare systems all over the world. Through clinical and preclinical investigations, inflammation and oxidative damage have been established as the primary causes of chronic wounds. These skin sores are easily exposed to microorganisms, which in turn cause inflammation and hinder the healing process. Additionally, microorganisms may cause an infection that prevents collagen production and reepithelialization. Curcumin’s antioxidant, anti-inflammatory, and anti-infectious characteristics, among others, have been identified as useful for diabetic wound healing management. However, curcumin has a few disadvantages, such as limited bioavailability, pH-dependent instability, water insolubility, slow cell absorption, and fast intracellular metabolism. These constraints necessitates the development of a suitable transporter to improve curcumin’s stability, bioavailability, therapeutic efficacy, and solubility. In recent years, Electrospun nanofiber mats have been an excellent choice for drug delivery because of their numerous advantages and inherent properties. Electrospun nanofibers have shown considerable promise as wound dressing materials. This review highlights the potential properties and recent advancements in using curcumin-loaded nanofibers for diabetic wound healing.
Keywords: curcumin; electrospinning; nanofibers; advanced delivery systems; skin tissue engineering; diabetic wound healing curcumin; electrospinning; nanofibers; advanced delivery systems; skin tissue engineering; diabetic wound healing
Graphical Abstract

Share and Cite

MDPI and ACS Style

Tamilarasi, G.P.; Krishnan, M.; Sabarees, G.; Gouthaman, S.; Alagarsamy, V.; Solomon, V.R. Emerging Trends in Curcumin Embedded Electrospun Nanofibers for Impaired Diabetic Wound Healing. Appl. Nano 2022, 3, 202-232. https://doi.org/10.3390/applnano3040015

AMA Style

Tamilarasi GP, Krishnan M, Sabarees G, Gouthaman S, Alagarsamy V, Solomon VR. Emerging Trends in Curcumin Embedded Electrospun Nanofibers for Impaired Diabetic Wound Healing. Applied Nano. 2022; 3(4):202-232. https://doi.org/10.3390/applnano3040015

Chicago/Turabian Style

Tamilarasi, Ganesan Padmini, Manikandan Krishnan, Govindaraj Sabarees, Siddan Gouthaman, Veerachamy Alagarsamy, and Viswas Raja Solomon. 2022. "Emerging Trends in Curcumin Embedded Electrospun Nanofibers for Impaired Diabetic Wound Healing" Applied Nano 3, no. 4: 202-232. https://doi.org/10.3390/applnano3040015

APA Style

Tamilarasi, G. P., Krishnan, M., Sabarees, G., Gouthaman, S., Alagarsamy, V., & Solomon, V. R. (2022). Emerging Trends in Curcumin Embedded Electrospun Nanofibers for Impaired Diabetic Wound Healing. Applied Nano, 3(4), 202-232. https://doi.org/10.3390/applnano3040015

Article Metrics

Back to TopTop