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Systematic Review

Therapeutic Role of Nystatin Added to Tissue Conditioners for Treating Denture-Induced Stomatitis: A Systematic Review

1
Department of Oral Biology, Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi 75510, Pakistan
2
Department of Substitutive Dental Sciences, College of Dentistry, Taibah University, Al Madinah, Al Munawwarah 41311, Saudi Arabia
3
Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia
4
Department of Oral Pathology, Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi 75510, Pakistan
5
Department of Restorative Dentistry, College of Dentistry, Taibah University, Al Madinah, Al Munawwarah 41311, Saudi Arabia
6
Department of Dental Materials, Islamic International Dental College, Riphah International University, Islamabad 44000, Pakistan
*
Author to whom correspondence should be addressed.
Prosthesis 2021, 3(1), 61-74; https://doi.org/10.3390/prosthesis3010007
Received: 28 December 2020 / Revised: 25 January 2021 / Accepted: 29 January 2021 / Published: 3 February 2021
(This article belongs to the Special Issue Tissue and Immunological Features of the Human/Prosthesis Interface)
Denture-induced stomatitis (DIS) represents a pathological condition caused by ill-fitting dentures trauma, manifested as inflammation of the palatal tissue beneath the denture. The fungal infections are the principal contributory factors to DIS. Although the aetiology of DIS is multifactorial, the Candida albicans fungal infection remains the main cause. The objective of the present systematic review was to evaluate the latest literature on the addition of nystatin into the tissue conditioners (TCs) in the management of DIS. To search the published literature about “the addition of nystatin in TCs for treating DIS”, electronic databases (PubMed (National library of medicine) and Cochrane Library (Wiley)) were searched (from 1975 until December 2020) using different keywords. Various studies described the effectiveness and efficacy of incorporating nystatin into several TCs. The present systematic review reported that the addition of nystatin is beneficial, with slight or no consequences on both the mechanical and physical features of TCs. Adding nystatin to various TCs for treating DIS can be suggested. View Full-Text
Keywords: antifungal; nystatin; tissue conditioner; prosthesis; Candida albicans; denture-induced stomatitis antifungal; nystatin; tissue conditioner; prosthesis; Candida albicans; denture-induced stomatitis
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MDPI and ACS Style

Shaikh, M.S.; Alnazzawi, A.; Habib, S.R.; Lone, M.A.; Zafar, M.S. Therapeutic Role of Nystatin Added to Tissue Conditioners for Treating Denture-Induced Stomatitis: A Systematic Review. Prosthesis 2021, 3, 61-74. https://doi.org/10.3390/prosthesis3010007

AMA Style

Shaikh MS, Alnazzawi A, Habib SR, Lone MA, Zafar MS. Therapeutic Role of Nystatin Added to Tissue Conditioners for Treating Denture-Induced Stomatitis: A Systematic Review. Prosthesis. 2021; 3(1):61-74. https://doi.org/10.3390/prosthesis3010007

Chicago/Turabian Style

Shaikh, Muhammad S., Ahmad Alnazzawi, Syed R. Habib, Mohid A. Lone, and Muhammad S. Zafar. 2021. "Therapeutic Role of Nystatin Added to Tissue Conditioners for Treating Denture-Induced Stomatitis: A Systematic Review" Prosthesis 3, no. 1: 61-74. https://doi.org/10.3390/prosthesis3010007

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