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Case Report
Peer-Review Record

Effective Lenvatinib Treatment Complicated with Secondary Tracheocutaneous Fistula in Patients with Advanced Anaplastic Thyroid Carcinoma

by Wen-Chi Wu 1, Jiun-I Lai 2,3, Jui-Yu Chen 4 and Chun-Yu Liu 2,3,5,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Submission received: 9 August 2019 / Revised: 30 August 2019 / Accepted: 1 September 2019 / Published: 5 September 2019
(This article belongs to the Special Issue Case Reports in Oncology)

Round 1

Reviewer 1 Report

MDPI

Review of the article entitled:

 

Effective lenvatinib treatment complicated with secondary tracheocutaneous fistula in patients with advanced anaplastic thyroid carcinoma

 

The authors report dramatic treatment effects of lenvatinib in two patients with stage IVc ATC

 

Unfortunately the article is hard to read because probably in the editing process, some spaces between the words disappeared, fusing two or sometimes more words together. Supplementary material should be translated into English

overall the article is interesting and suitable for publication after proofreading

Author Response

Dear reviewer:

We fully understand the importance of addressing the issues raised by the reviewers, and all suggestions have been incorporated into our revised manuscript. All changes are coded in blue by using the “Track Changes” function. Point-by-point responses are outlined in the following pages

Point 1: The article is hard to read because probably in the editing process, some spaces between the words disappeared, fusing two or sometimes more words together. 

Response 1: Thanks for your kind reminder. We proofread the article and inserted the blanks between the fusing words.

Point 2: Supplementary material should be translated into English

Response 2: We translated the supplementary material into English. Please see the attachment.

 

Author Response File: Author Response.doc

Reviewer 2 Report

The authors present two cases with anaplastic thyroid cancer treated with lenvatinib resulting in dramatic treatment effects and the development of tracheal perforation and fistula formation. The manuscript is well written! However, there are only some small issues need to be solved:

Please insert blank spaces between some words e.g. line 27,29...

Author Response

Dear reviewer:

We fully understand the importance of addressing the issues raised by the reviewers, and all suggestions have been incorporated into our revised manuscript. Point-by-point responses are outlined as followings,

Point 1: Please insert blank spaces between some words e.g. line 27,29... 

Response 1: Thanks for your kind reminder. We proofread the article and inserted the blanks between fusing words.

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