Advances in Respiratory Medicine, Volume 76, Issue 2

Introduction: Plasminogen inhibitor activator type 1 (PAI-1) is an important regulator of tumor growth and metastasis formation acting directly via specific urokinase complexing or indirectly due to its affinity to vitronectin. We have shown previous...

Introduction: Asthma is a disease with a complex pathogenesis. Obesity seems to be crucial risk factor for the development and worse clinical outcome of the disease. The aim of the study was to assess the relation between the body weight and the seve...

Patients after organ transplantations are at risk for mycobacteriosis development. Frequency of the mycobacterial infection after bone marrow transplantation (BMT) is not as high as one could expect. It ranges from 0.4 to 4.9%. We present a case of a...

Amiodarone, antiarrhythmic drug of III class is used in patients with supraventricular and ventricular arrhythmias, often with coexisting congestive heart failure. Side effects of amiodarone treatment are observed in approximately 75% of patients. Mo...

Corticosteroids (CS) have been used for many years and proved to be the most effective treatment in asthmatic patients. They are controllers of choice in the management of most adult patients with asthma. CS reduce asthma symptoms, improve lung funct...

Introduction: The aim of this study was to assess results of 6MWT in non-selected group of obstructive sleep apnoea (OSA) patients. In healthy adult subjects 6-minute walking distance (6MWD) range from 400 to 700 m. Obesity, the main symptom of OSA,...

Introduction: Gastroesophageal reflux (GERD) is a frequent disease in patients with obstructive sleep apnea (OSA). The aim of the study was to evaluate possible correlation between the impairement of exercise tolerance and GERD. Material and methods:...