A Fast L2-1σ Finite Element Method for Time Fractional Keller–Segel Equations with Weakly Singular Solutions
Abstract
1. Introduction
- We consider for the first time the numerical method for solving singular cases in the fractional KS models. Compared to the smooth case in reference [27], our numerical method is more in line with the characteristics of fractional order models.
- A fast numerical scheme is obtained by constructing a fast nonuniform L2-1σ scheme with the finite element method for the time fractional Keller–Segel equations. This numerical scheme has the advantages of high accuracy and low computational storage and can effectively handle the singularity of the solution at .
- We prove the stability of the numerical scheme for both the and norms under some constraints on the time step ratio and obtain a -robust error estimate by the fractional Grönwall inequality. We note that this theoretical analysis framework is also applicable to the more complex time fractional-order coupled diffusion systems [47].
2. Fully Discrete Scheme for the TFKS Equations
3. Stability Analysis of Fully Discrete Scheme
4. Error Analysis of the Fully Discrete Scheme
5. Numerical Experiment
6. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
- Magin, R.L. Fractional calculus models of complex dynamics in biological tissues. Comput. Math. Appl. 2010, 59, 1586–1593. [Google Scholar] [CrossRef]
- Hilfer, R. Applications of Fractional Calculus in Physics; World Scientific: Singapore, 2000. [Google Scholar]
- Caponetto, R.; Dongola, G.; Fortuna, L.; Petras, I. Fractional Order Systems: Modeling and Control Applications; World Scientific: Singapore, 2010; Volume 72. [Google Scholar]
- Lord, R.; Fang, F.; Bervoets, F.; Oosterlee, C.W. A fast and accurate FFT-based method for pricing early-exercise options under Lévy processes. SIAM J. Sci. Comput. 2008, 30, 1678–1705. [Google Scholar] [CrossRef]
- Keller, E.F.; Segel, L.A. Initiation of slime mold aggregation viewed as an instability. J. Theor. Biol. 1970, 26, 399–415. [Google Scholar] [CrossRef]
- Keller, E.F.; Segel, L.A. Traveling bands of chemotactic bacteria: A theoretical analysis. J. Theor. Biol. 1971, 30, 235–248. [Google Scholar] [CrossRef]
- Haastert, P.J.M.V.; Devreotes, P.N. Chemotaxis: Signalling the way forward. Nat. Rev. Mol. Cell Biol. 2004, 5, 626–634. [Google Scholar] [CrossRef] [PubMed]
- Hillen, T.; Painter, K.J. A user’s guide to PDE models for chemotaxis. J. Math. Biol. 2009, 58, 183–217. [Google Scholar] [CrossRef]
- Eisenbach, M. Chemotaxis; World Scientific Publishing Company: Singapore, 2004. [Google Scholar]
- Feder, T.J.; Brust-Mascher, I.; Slattery, J.P.; Baird, B.; Webb, W.W. Constrained diffusion or immobile fraction on cell surfaces: A new interpretation. Biophys. J. 1996, 70, 2767–2773. [Google Scholar] [CrossRef]
- Banks, D.S.; Fradin, C. Anomalous diffusion of proteins due to molecular crowding. Biophys. J. 2005, 89, 2960–2971. [Google Scholar] [CrossRef]
- Weiss, M.; Hashimoto, H.; Nilsson, T. Anomalous protein diffusion in living cells as seen by fluorescence correlation spectroscopy. Biophys. J. 2003, 84, 4043–4052. [Google Scholar] [CrossRef]
- Metzler, R.; Klafter, J. The random walk’s guide to anomalous diffusion: A fractional dynamics approach. Phys. Rep. 2000, 339, 1–77. [Google Scholar] [CrossRef]
- Langlands, T.A.M.; Henry, B.I. Fractional chemotaxis diffusion equations. Phys. Rev. E 2010, 81, 051102. [Google Scholar] [CrossRef] [PubMed]
- Naghibolhosseini, M. Estimation of Outer-Middle Ear Transmission Using DPOAEs and Fractional-Order Modeling of Human Middle Ear. Ph.D. Thesis, City University of New York, New York, NY, USA, 2015. [Google Scholar]
- Li, L.; Liu, J.G. Some compactness criteria for weak solutions of time fractional PDEs. SIAM J. Math. Anal. 2018, 50, 3963–3995. [Google Scholar] [CrossRef]
- Zhou, Y.; Manimaran, J.; Shangerganesh, L.; Debbouche, A. Weakness and Mittag–Leffler stability of solutions for time-fractional Keller–Segel models. Int. J. Nonlinear Sci. Numer. Simul. 2018, 19, 753–761. [Google Scholar] [CrossRef]
- Aruchamy, A.; Tyagi, J. Nonnegative solutions to time fractional Keller–Segel system. Math. Methods Appl. Sci. 2021, 44, 1812–1830. [Google Scholar] [CrossRef]
- Bezerra, M.; Cuevas, C.; Silva, C.; Soto, H. On the fractional doubly parabolic Keller-Segel system modelling chemotaxis. Sci. China Math. 2022, 65, 1827–1874. [Google Scholar] [CrossRef]
- Costa, M.; Cuevas, C.; Silva, C.; Soto, H. Well-posedness and blow-up of the fractional Keller–Segel model on domains. Math. Nachrichten 2023, 296, 5569–5592. [Google Scholar] [CrossRef]
- El-Sayed, A.M.A.; Rida, S.Z.; Arafa, A.A.M. On the solutions of time-fractional bacterial chemotaxis in a diffusion gradient chamber. Int. J. Nonlinear Sci. 2009, 7, 485–492. [Google Scholar]
- Kumar, S.; Kumar, A.; Argyros, I.K. A new analysis for the Keller–Segel model of fractional order. Numer. Algorithms 2017, 75, 213–228. [Google Scholar] [CrossRef]
- Dokuyucu, M.A.; Baleanu, D.; Çelik, E. Analysis of Keller–Segel model with Atangana-Baleanu fractional derivative. Filomat 2018, 32, 5633–5643. [Google Scholar] [CrossRef]
- Morales-Delgado, V.F.; Gómez-Aguilar, J.F.; Kumar, S.; Taneco-Hernández, M.A. Analytical solutions of the Keller–Segel chemotaxis model involving fractional operators without singular kernel. Eur. Phys. J. Plus 2018, 133, 200. [Google Scholar] [CrossRef]
- Nguyen, A.T.; Tuan, N.H.; Yang, C. On cauchy problem for fractional parabolic-elliptic Keller–Segel model. Adv. Nonlinear Anal. 2022, 12, 97–116. [Google Scholar] [CrossRef]
- Khaider, H.; El-Ouaarabi, M.; Raji, A. An Global existence and uniqueness of mild solution for a fractional Keller-Segel system in Besov-Morrey spaces. Math. Model. Anal. 2025, 30, 685–706. [Google Scholar] [CrossRef]
- Zayernouri, M.; Matzavinos, A. Fractional Adams–Bashforth/Moulton methods: An application to the fractional Keller–Segel chemotaxis system. J. Comput. Phys. 2016, 317, 1–14. [Google Scholar] [CrossRef]
- Sakamoto, K.; Yamamoto, M. Initial value/boundary value problems for fractional diffusion-wave equations and applications to some inverse problems. J. Math. Anal. Appl. 2011, 382, 426–447. [Google Scholar] [CrossRef]
- Stynes, M.; O’Riordan, E.; Gracia, J.L. Error analysis of a finite difference method on graded meshes for a time-fractional diffusion equation. SIAM J. Numer. Anal. 2017, 55, 1057–1079. [Google Scholar] [CrossRef]
- Liao, H.L.; Li, D.F.; Zhang, J.W. Sharp error estimate of the nonuniform L1 formula for linear reaction-subdiffusion equations. SIAM J. Numer. Anal. 2018, 56, 1112–1133. [Google Scholar] [CrossRef]
- Kopteva, N. Error analysis of the L1 method on graded and uniform meshes for a fractional-derivative problem in two and three dimensions. Math. Comput. 2019, 88, 2135–2155. [Google Scholar] [CrossRef]
- Chen, H.; Stynes, M. Error analysis of a second-order method on fitted meshes for a time-fractional diffusion problem. J. Sci. Comput. 2019, 79, 624–647. [Google Scholar] [CrossRef]
- Kopteva, N. Error analysis of an L2-type method on graded meshes for a fractional-order parabolic problem. Math. Comput. 2021, 90, 19–40. [Google Scholar] [CrossRef]
- Huang, C.B.; Stynes, M. A sharp α-robust L∞(H1) error bound for a time-fractional Allen–Cahn problem discretised by the Alikhanov L2-1σ scheme and a standard FEM. J. Sci. Comput. 2022, 91, 43. [Google Scholar] [CrossRef]
- Mustapha, K.; Abdallah, B.; Furati, K.M. A discontinuous Petrov–Galerkin method for time-fractional diffusion equations. SIAM J. Numer. Anal. 2014, 52, 2512–2529. [Google Scholar] [CrossRef]
- Jin, B.T.; Li, B.Y.; Zhou, Z. Correction of high-order bdf convolution quadrature for fractional evolution equations. SIAM J. Sci. Comput. 2017, 39, A3129–A3152. [Google Scholar] [CrossRef]
- Jin, B.T.; Li, B.Y.; Zhou, Z. Subdiffusion with time-dependent coefficients: Improved regularity and second-order time stepping. Numer. Math. 2020, 145, 883–913. [Google Scholar] [CrossRef]
- Xing, Y.Y.; Yan, Y.B. A higher order numerical method for time fractional partial differential equations with nonsmooth data. J. Comput. Phys. 2018, 357, 305–323. [Google Scholar] [CrossRef]
- Yan, Y.B.; Khan, M.; Ford, N.J. An analysis of the modified L1 scheme for time-fractional partial differential equations with nonsmooth data. SIAM J. Numer. Anal. 2018, 56, 210–227. [Google Scholar] [CrossRef]
- Jiang, S.D.; Zhang, J.W.; Zhang, Q.; Zhang, Z.M. Fast evaluation of the Caputo fractional derivative and its applications to fractional diffusion equations. Commun. Comput. Phys. 2017, 21, 650–678. [Google Scholar] [CrossRef]
- Liao, H.L.; Yan, Y.G.; Zhang, J.W. Unconditional convergence of a fast two-level linearized algorithm for semilinear subdiffusion equations. J. Sci. Comput. 2019, 80, 1–25. [Google Scholar] [CrossRef]
- Yan, Y.G.; Sun, Z.Z.; Zhang, J.W. Fast evaluation of the Caputo fractional derivative and its applications to fractional diffusion equations: A second-order scheme. Commun. Comput. Phys. 2017, 22, 1028–1048. [Google Scholar] [CrossRef]
- Zhu, H.Y.; Xu, C.J. A fast high order method for the time-fractional diffusion equation. SIAM J. Numer. Anal. 2019, 57, 2829–2849. [Google Scholar] [CrossRef]
- Liu, N.; Chen, Y.P.; Zhang, J.W.; Zhao, Y.M. Unconditionally optimal h 1-error estimate of a fast nonuniform L2-1σ scheme for nonlinear subdiffusion equations. Numer. Algorithms 2023, 92, 1655–1677. [Google Scholar] [CrossRef]
- Li, Q.; Xie, J. A fast second order PDE approach for the space-time fractional parabolic problems. AIMS Math. 2025, 10, 25568–25588. [Google Scholar] [CrossRef]
- Zeng, Y.; Tan, Z. An α-robust two-grid finite element method with nonuniform L2-1Σ scheme for the semilinear Caputo-Hadamard time-fractional diffusion equations involving initial singularity. Appl. Math. Comput. 2025, 496, 129355. [Google Scholar]
- Garrappa, R.; Moret, I.; Popolizio, M. Solving the time-fractional Schrödinger equation by Krylov projection methods. J. Comput. Phys. 2015, 293, 115–134. [Google Scholar] [CrossRef]
- Alikhanov, A.A. A new difference scheme for the time fractional diffusion equation. J. Comput. Phys. 2015, 280, 424–438. [Google Scholar] [CrossRef]
- Li, X.; Liao, H.L.; Zhang, L.M. A second-order fast compact scheme with unequal time-steps for subdiffusion problems. Numer. Algorithms 2021, 86, 1011–1039. [Google Scholar] [CrossRef]
- Wang, Y.B.; An, N.; Huang, C.B. Unconditional optimal error bounds of the fast nonuniform Alikhanov scheme for a nonlinear time-fractional biharmonic equation. J. Appl. Math. Comput. 2024, 70, 4053–4071. [Google Scholar] [CrossRef]
- Thomée, V. Galerkin Finite Element Methods for Parabolic Problems; Springer Science & Business Media: Berlin/Heidelberg, Germany, 2007; Volume 25. [Google Scholar]
- Chen, H.; Stynes, M. Blow-up of error estimates in time-fractional initial-boundary value problems. IMA J. Numer. Anal. 2021, 41, 974–997. [Google Scholar] [CrossRef]


| h | Rate | Rate | Rate | Rate | |||||
|---|---|---|---|---|---|---|---|---|---|
| 0.8 | 1.3527 × 10−3 | – | 4.5514 × 10−2 | – | 1.0776 × 10−4 | – | 3.6208 × 10−3 | – | |
| 2.6193 × 10−4 | 2.3686 | 2.2136 × 10−2 | 1.0399 | 2.0876 × 10−5 | 2.3679 | 1.7614 × 10−3 | 1.0396 | ||
| 5.9070 × 10−5 | 2.1487 | 1.0954 × 10−2 | 1.0149 | 4.6869 × 10−6 | 2.1551 | 8.7172 × 10−4 | 1.0148 | ||
| 1.4979 × 10−5 | 1.9795 | 5.4615 × 10−3 | 1.0041 | 1.1450 × 10−6 | 2.0333 | 4.3463 × 10−4 | 1.0041 | ||
| 0.9 | 6.6022 × 10−4 | – | 2.3059 × 10−2 | – | 5.2545 × 10−5 | – | 1.8348 × 10−3 | – | |
| 1.2279 × 10−4 | 2.4267 | 1.1145 × 10−2 | 1.0490 | 9.7748 × 10−6 | 2.4264 | 8.8684 × 10−4 | 1.0489 | ||
| 2.6402 × 10−5 | 2.2175 | 5.4992 × 10−3 | 1.0191 | 2.1014 × 10−6 | 2.2177 | 4.3761 × 10−4 | 1.0190 | ||
| 6.3036 × 10−6 | 2.0664 | 2.7391 × 10−3 | 1.0055 | 4.9967 × 10−7 | 2.0723 | 2.1797 × 10−4 | 1.0055 | ||
| 0.95 | 4.6514 × 10−4 | – | 1.6385 × 10−2 | – | 3.7016 × 10−5 | – | 1.3038 × 10−3 | – | |
| 8.5618 × 10−5 | 2.4417 | 7.9053 × 10−3 | 1.0515 | 6.8140 × 10−6 | 2.4416 | 6.2907 × 10−4 | 1.0514 | ||
| 1.8064 × 10−5 | 2.2448 | 3.8966 × 10−3 | 1.0206 | 1.4378 × 10−6 | 2.2447 | 3.1008 × 10−4 | 1.0206 | ||
| 4.2409 × 10−6 | 2.0907 | 1.9399 × 10−3 | 1.0062 | 3.3717 × 10−7 | 2.0923 | 1.5437 × 10−4 | 1.0062 |
| N | Rate | Rate | |||
|---|---|---|---|---|---|
| 0.8 | 4 | 4.6535 × 10−4 | − | 4.0864 × 10−5 | − |
| 8 | 1.4175 × 10−4 | 1.7149 | 1.2460 × 10−5 | 1.7135 | |
| 16 | 3.7849 × 10−5 | 1.9051 | 3.2314 × 10−6 | 1.9471 | |
| 32 | 1.0781 × 10−5 | 1.8118 | 7.9979 × 10−7 | 2.0145 | |
| 0.9 | 4 | 1.2799 × 10−4 | − | 1.0654 × 10−5 | − |
| 8 | 3.8748 × 10−5 | 1.7238 | 3.2209 × 10−6 | 1.7258 | |
| 16 | 1.0290 × 10−5 | 1.9129 | 8.4453 × 10−7 | 1.9312 | |
| 32 | 2.7964 × 10−6 | 1.8796 | 2.1743 × 10−7 | 1.9576 | |
| 0.95 | 4 | 4.6330 × 10−5 | − | 3.7983 × 10−6 | − |
| 8 | 1.3992 × 10−5 | 1.7274 | 1.1443 × 10−6 | 1.7309 | |
| 16 | 3.7566 × 10−6 | 1.8971 | 3.0351 × 10−7 | 1.9147 | |
| 32 | 1.0897 × 10−6 | 1.7855 | 8.4279 × 10−8 | 1.8485 |
| N | 800 | 1000 | 1200 | 1400 | 1600 |
|---|---|---|---|---|---|
| L2-1σ/FEM scheme | 134.128 s | 208.3286 s | 338.0771 s | 673.9065 s | 900.8299 s |
| Fast L2-1σ/FEM scheme | 94.9092 s | 167.8129 s | 222.4437 s | 310.5037 s | 328.4481 s |
| h | Rate | Rate | Rate | Rate | |||||
|---|---|---|---|---|---|---|---|---|---|
| 0.8 | 2.6299 × 10−5 | – | 6.3752 × 10−4 | – | 5.2618 × 10−6 | – | 1.2748 × 10−4 | – | |
| 5.2585 × 10−6 | 2.3223 | 3.1209 × 10−4 | 1.0305 | 1.0528 × 10−6 | 2.3213 | 6.2412 × 10−5 | 1.0303 | ||
| 1.1810 × 10−6 | 2.1547 | 1.5406 × 10−4 | 1.0185 | 2.3662 × 10−7 | 2.1536 | 3.0811 × 10−5 | 1.0184 | ||
| 2.8548 × 10−7 | 2.0485 | 7.6730 × 10−5 | 1.0056 | 5.7217 × 10−8 | 2.0481 | 1.5346 × 10−5 | 1.0056 | ||
| 0.9 | 1.2896 × 10−5 | – | 3.2526 × 10−4 | – | 2.5793 × 10−6 | – | 6.5049 × 10−5 | – | |
| 2.4591 × 10−6 | 2.3907 | 1.5789 × 10−4 | 1.0427 | 4.9192 × 10−7 | 2.3905 | 3.1577 × 10−5 | 1.0427 | ||
| 5.2117 × 10−7 | 2.2383 | 7.7482 × 10−5 | 1.0270 | 1.0429 × 10−7 | 2.2379 | 1.5496 × 10−5 | 1.0269 | ||
| 1.2231 × 10−7 | 2.0912 | 3.8500 × 10−5 | 1.0090 | 2.4481 × 10−8 | 2.0908 | 7.7001 × 10−6 | 1.0090 | ||
| 0.95 | 9.0968 × 10−6 | – | 2.3155 × 10−4 | – | 1.8194 × 10−6 | – | 4.6309 × 10−5 | – | |
| 1.7121 × 10−6 | 2.4096 | 1.1223 × 10−4 | 1.0449 | 3.4244 × 10−7 | 2.4095 | 2.2446 × 10−5 | 1.0448 | ||
| 3.5306 × 10−7 | 2.2778 | 5.4960 × 10−5 | 1.0301 | 7.0629 × 10−8 | 2.2775 | 1.0992 × 10−5 | 1.0300 | ||
| 8.1251 × 10−8 | 2.1195 | 2.7276 × 10−5 | 1.0107 | 1.6257 × 10−8 | 2.1192 | 5.4552 × 10−6 | 1.0107 |
| N | Rate | Rate | |||
|---|---|---|---|---|---|
| 0.8 | 4 | 1.9447 × 10−6 | – | 4.0582 × 10−7 | – |
| 8 | 5.7268 × 10−7 | 1.7637 | 1.2009 × 10−7 | 1.7567 | |
| 16 | 1.5138 × 10−7 | 1.9195 | 3.1711 × 10−8 | 1.9211 | |
| 32 | 4.9146 × 10−8 | 1.6231 | 1.0095 × 10−8 | 1.6513 | |
| 0.9 | 4 | 6.3564 × 10−7 | – | 1.2934 × 10−7 | – |
| 8 | 1.9213 × 10−7 | 1.7261 | 3.9116 × 10−8 | 1.7253 | |
| 16 | 5.2613 × 10−8 | 1.8686 | 1.0696 × 10−8 | 1.8707 | |
| 32 | 1.8532 × 10−8 | 1.5054 | 3.7373 × 10−9 | 1.5170 | |
| 0.95 | 4 | 2.4057 × 10−7 | – | 4.8654 × 10−8 | – |
| 8 | 7.3227 × 10−8 | 1.7160 | 1.4809 × 10−8 | 1.7161 | |
| 16 | 2.1337 × 10−8 | 1.7790 | 4.3061 × 10−9 | 1.7820 | |
| 32 | 9.8102 × 10−9 | 1.1210 | 1.9678 × 10−9 | 1.1298 |
| N | Rate | Rate | |||
|---|---|---|---|---|---|
| 0.8 | 4 | 1.9387 × 10−6 | – | 4.046 × 10−7 | – |
| 8 | 5.6607 × 10−7 | 1.7760 | 1.1876 × 10−7 | 1.7685 | |
| 16 | 1.4301 × 10−7 | 1.9849 | 3.0036 × 10−8 | 1.9832 | |
| 32 | 3.539 × 10−8 | 2.0147 | 7.3613 × 10−9 | 2.0287 | |
| 0.9 | 4 | 6.3406 × 10−7 | – | 1.2902 × 10−7 | – |
| 8 | 1.9028 × 10−7 | 1.7365 | 3.8746 × 10−8 | 1.7355 | |
| 16 | 4.9802 × 10−8 | 1.9338 | 1.0136 × 10−8 | 1.9345 | |
| 32 | 1.2933 × 10−8 | 1.9452 | 2.6221 × 10−9 | 1.9508 | |
| 0.95 | 4 | 2.3972 × 10−7 | – | 4.8484 × 10−8 | – |
| 8 | 7.2087 × 10−8 | 1.7335 | 1.4581 × 10−8 | 1.7334 | |
| 16 | 1.9153 × 10−8 | 1.9122 | 3.8711 × 10−9 | 1.9133 | |
| 32 | 5.3333 × 10−9 | 1.8444 | 1.0739 × 10−9 | 1.8499 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Li, Q.; Xie, J.; Chen, S. A Fast L2-1σ Finite Element Method for Time Fractional Keller–Segel Equations with Weakly Singular Solutions. Fractal Fract. 2026, 10, 119. https://doi.org/10.3390/fractalfract10020119
Li Q, Xie J, Chen S. A Fast L2-1σ Finite Element Method for Time Fractional Keller–Segel Equations with Weakly Singular Solutions. Fractal and Fractional. 2026; 10(2):119. https://doi.org/10.3390/fractalfract10020119
Chicago/Turabian StyleLi, Qingfeng, Jia Xie, and Shirong Chen. 2026. "A Fast L2-1σ Finite Element Method for Time Fractional Keller–Segel Equations with Weakly Singular Solutions" Fractal and Fractional 10, no. 2: 119. https://doi.org/10.3390/fractalfract10020119
APA StyleLi, Q., Xie, J., & Chen, S. (2026). A Fast L2-1σ Finite Element Method for Time Fractional Keller–Segel Equations with Weakly Singular Solutions. Fractal and Fractional, 10(2), 119. https://doi.org/10.3390/fractalfract10020119
