Factors Contributing to In-Hospital Mortality in Dengue: Insights from National Surveillance Data in Mexico (2020–2024)
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Characteristic | Dengue Outcome | ||
---|---|---|---|
Recovery (n = 18,113) | Death (n = 323) | ||
Sex | |||
Female | 9923 (54.8) | 170 (52.6) | 0.441 |
Male | 8190 (45.2) | 153 (47.4) | |
Age (mean ± SD, years) | 24.5 ± 17.4 | 35.5 ± 25.4 | <0.001 |
Age group (years) | |||
0–9 | 3098 (17.1) | 53 (16.4) | <0.001 |
10–19 | 6098 (33.7) | 66 (20.4) | |
20–29 | 3407 (18.8) | 39 (12.1) | |
30–39 | 2154 (11.9) | 35 (10.8) | |
40–49 | 1407 (7.8) | 32 (9.9) | |
50–59 | 962 (5.3) | 32 (9.9) | |
60–69 | 580 (3.2) | 24 (7.4) | |
70 or above | 407 (2.3) | 42 (13.0) | |
Isolated serotype | |||
DENV-1 | 2265 (12.5) | 21 (6.5) | 0.009 |
DENV-2 | 6970 (38.5) | 141 (43.7) | |
DENV-3 | 8650 (47.8) | 156 (48.3) | |
DENV-4 | 228 (1.3) | 5 (1.6) | |
Type 2 diabetes mellitus | |||
No | 17,488 (96.6) | 271 (83.9) | <0.001 |
Yes | 625 (3.4) | 52 (16.1) | |
Hypertensive disease | |||
No | 17,680 (97.6) | 285 (88.2) | <0.001 |
Yes | 433 (2.4) | 38 (11.8) | |
Chronic kidney disease | |||
No | 18,030 (99.5) | 307 (95.1) | <0.001 |
Yes | 83 (0.5) | 16 (4.9) | |
Immunosuppression (any cause) | |||
No | 18,074 (99.8) | 320 (99.1) | 0.008 |
Yes | 39 (0.2) | 3 (0.9) |
Bivariate Analysis | Multiple Analysis | |
---|---|---|
Sex | ||
Female | 1.00 | 1.00 |
Male | 1.09 (0.88–1.35), 0.441 | 1.12 (0.90–1.39), 0.300 |
Age (years) | 1.03 (1.02–1.04), <0.001 | 1.02 (1.01–1.03), <0.001 |
Isolated serotype | ||
DENV-1 | 1.00 | 1.00 |
DENV-2 | 2.16 (1.37–3.41), 0.001 | 1.81 (1.15–2.86), 0.010 |
DENV-3 | 1.93 (1.23–3.03), 0.005 | 1.87 (1.19–2.92), 0.007 |
DENV-4 | 2.34 (0.89–6.14), 0.085 | 1.88 (0.73–4.86), 0.190 |
Type 2 diabetes mellitus | ||
No | 1.00 | 1.00 |
Yes | 5.03 (3.78–6.70), <0.001 | 2.07 (1.45–2.96), <0.001 |
Hypertensive disease | ||
No | 1.00 | 1.00 |
Yes | 5.09 (3.67–7.04), <0.001 | 1.49 (0.99–2.23), 0.054 |
Chronic kidney disease | ||
No | 1.00 | 1.00 |
Yes | 9.65 (6.08–15.32), <0.001 | 3.35 (2.03–5.51), <0.001 |
Immunosuppression (any cause) | ||
No | 1.00 | 1.00 |
Yes | 4.11(1.37–12.28), 0.012 | 2.86 (0.99–8.29), 0.053 |
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Ríos-Bracamontes, E.F.; Mendoza-Cano, O.; Lugo-Radillo, A.; Ortega-Ramírez, A.D.; Murillo-Zamora, E. Factors Contributing to In-Hospital Mortality in Dengue: Insights from National Surveillance Data in Mexico (2020–2024). Trop. Med. Infect. Dis. 2024, 9, 202. https://doi.org/10.3390/tropicalmed9090202
Ríos-Bracamontes EF, Mendoza-Cano O, Lugo-Radillo A, Ortega-Ramírez AD, Murillo-Zamora E. Factors Contributing to In-Hospital Mortality in Dengue: Insights from National Surveillance Data in Mexico (2020–2024). Tropical Medicine and Infectious Disease. 2024; 9(9):202. https://doi.org/10.3390/tropicalmed9090202
Chicago/Turabian StyleRíos-Bracamontes, Eder Fernando, Oliver Mendoza-Cano, Agustin Lugo-Radillo, Ana Daniela Ortega-Ramírez, and Efrén Murillo-Zamora. 2024. "Factors Contributing to In-Hospital Mortality in Dengue: Insights from National Surveillance Data in Mexico (2020–2024)" Tropical Medicine and Infectious Disease 9, no. 9: 202. https://doi.org/10.3390/tropicalmed9090202
APA StyleRíos-Bracamontes, E. F., Mendoza-Cano, O., Lugo-Radillo, A., Ortega-Ramírez, A. D., & Murillo-Zamora, E. (2024). Factors Contributing to In-Hospital Mortality in Dengue: Insights from National Surveillance Data in Mexico (2020–2024). Tropical Medicine and Infectious Disease, 9(9), 202. https://doi.org/10.3390/tropicalmed9090202