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Communication

A Practical Approach to Screening for Strongyloides stercoralis

by
Luisa Carnino
1,2,*,
Jean-Marc Schwob
1,
Laurent Gétaz
3,
Beatrice Nickel
4,5,
Andreas Neumayr
4,5 and
Gilles Eperon
1,2
1
Division of Tropical and Humanitarian Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 6, 1205 Geneva, Switzerland
2
Faculty of Medicine, University of Geneva, Rue Michel-Servet 1, 1205 Geneva, Switzerland
3
Division of Penitentiary Medicine, Geneva University Hospitals and University of Geneva, Ch. du Petit-Bel-Air 2, 1225 Chêne-Bourg, Switzerland
4
Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051 Basel, Switzerland
5
University of Basel, Klingelbergstrasse 61, 4056 Basel, Switzerland
*
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2021, 6(4), 203; https://doi.org/10.3390/tropicalmed6040203
Submission received: 18 October 2021 / Revised: 17 November 2021 / Accepted: 26 November 2021 / Published: 29 November 2021
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Abstract

Strongyloides stercoralis, causative agent of a neglected tropical disease, is a soil-transmitted helminth which may cause lifelong persisting infection due to continuous autoinfection. In the case of immunosuppression, life-threatening hyperinfection and disseminated strongyloidiasis can develop. We propose a pragmatic screening algorithm for latent strongyloidiasis based on epidemiologic exposure and immunosuppression status that can be applied for any kind of immunosuppressive therapy. The algorithm allows the diagnosis of latent strongyloidiasis with optimal accuracy in a well-equipped setting, while for endemic settings where the complete testing array is unavailable, an empiric treatment is generally recommended. Accurate diagnosis and extensive empiric treatment will both contribute to decreasing the current neglect of strongyloidiasis.
Keywords: strongyloidiasis; immunosuppression; screening; corticosteroids; SARS-CoV-2 strongyloidiasis; immunosuppression; screening; corticosteroids; SARS-CoV-2

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MDPI and ACS Style

Carnino, L.; Schwob, J.-M.; Gétaz, L.; Nickel, B.; Neumayr, A.; Eperon, G. A Practical Approach to Screening for Strongyloides stercoralis. Trop. Med. Infect. Dis. 2021, 6, 203. https://doi.org/10.3390/tropicalmed6040203

AMA Style

Carnino L, Schwob J-M, Gétaz L, Nickel B, Neumayr A, Eperon G. A Practical Approach to Screening for Strongyloides stercoralis. Tropical Medicine and Infectious Disease. 2021; 6(4):203. https://doi.org/10.3390/tropicalmed6040203

Chicago/Turabian Style

Carnino, Luisa, Jean-Marc Schwob, Laurent Gétaz, Beatrice Nickel, Andreas Neumayr, and Gilles Eperon. 2021. "A Practical Approach to Screening for Strongyloides stercoralis" Tropical Medicine and Infectious Disease 6, no. 4: 203. https://doi.org/10.3390/tropicalmed6040203

APA Style

Carnino, L., Schwob, J.-M., Gétaz, L., Nickel, B., Neumayr, A., & Eperon, G. (2021). A Practical Approach to Screening for Strongyloides stercoralis. Tropical Medicine and Infectious Disease, 6(4), 203. https://doi.org/10.3390/tropicalmed6040203

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