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Trop. Med. Infect. Dis. 2018, 3(1), 31; https://doi.org/10.3390/tropicalmed3010031

Melioidosis in Singapore: Clinical, Veterinary, and Environmental Perspectives

1
Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
2
Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
3
Laboratories Group, Agri-Food & Veterinary Authority of Singapore, Singapore 718827, Singapore
4
Food Establishment Regulation Group, Agri-Food & Veterinary Authority of Singapore, Singapore 608550, Singapore
5
Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore 729826, Singapore
6
Department of Infectious Diseases, Singapore General Hospital, Singapore 169608, Singapore
7
Division of Infectious Diseases, Department of Medicine, National University Health System, Singapore 119228, Singapore
8
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
9
National University Cancer Institute, Singapore 119074, Singapore
These authors contributed equally to this report.
*
Author to whom correspondence should be addressed.
Received: 7 February 2018 / Revised: 23 February 2018 / Accepted: 7 March 2018 / Published: 12 March 2018
(This article belongs to the Special Issue Global Burden and Challenges of Melioidosis)
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Abstract

Melioidosis is a notifiable infectious disease registered with the Ministry of Health (MOH) and Agri-Food & Veterinary Authority (AVA), Singapore. From a clinical perspective, increased awareness of the disease has led to early detection and treatment initiation, thus resulting in decreasing mortality rates in recent years. However, the disease still poses a threat to local pet, zoo and farm animals, where early diagnosis is a challenge. The lack of routine environmental surveillance studies also makes prevention of the disease in animals difficult. To date, there have been no reports that provide a complete picture of how the disease impacts the local human and animal populations in Singapore. Information on the distribution of Burkholderia pseudomallei in the environment is also lacking. The aim of this review is to provide a comprehensive overview of both published and unpublished clinical, veterinary and environmental studies on melioidosis in Singapore to achieve better awareness and management of the disease. View Full-Text
Keywords: melioidosis; B. pseudomallei; Singapore; clinical; veterinary; environmental melioidosis; B. pseudomallei; Singapore; clinical; veterinary; environmental
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Sim, S.H.; Ong, C.E.L.; Gan, Y.H.; Wang, D.; Koh, V.W.H.; Tan, Y.K.; Wong, M.S.Y.; Chew, J.S.W.; Ling, S.F.; Tan, B.Z.Y.; Ye, A.Z.; Bay, P.C.K.; Wong, W.K.; Fernandez, C.J.; Xie, S.; Jayarajah, P.; Tahar, T.; Oh, P.Y.; Luz, S.; Chien, J.M.F.; Tan, T.T.; Chai, L.Y.A.; Fisher, D.; Liu, Y.; Loh, J.J.P.; Tan, G.G.Y. Melioidosis in Singapore: Clinical, Veterinary, and Environmental Perspectives. Trop. Med. Infect. Dis. 2018, 3, 31.

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