Next Article in Journal
Progress for Journal of Functional Morphology and Kinesiology in 2017
Next Article in Special Issue
Physical Therapy Considerations for Chronic Kidney Disease and Secondary Sarcopenia
Previous Article in Journal
Shaping the Cell and the Future: Recent Advancements in Biophysical Aspects Relevant to Regenerative Medicine
Previous Article in Special Issue
Long-Term Benefits of Adapted Physical Activity on Upper Limb Performance and Quality of Life in Breast Cancer Survivors
Open AccessArticle

Diabetes Type 2 and Physical Activity Program: Potential Application of Risk-Engine UKPDS Score in Out-Patient Context

Sports and Exercise Medicine Center, University of Florence, 50139 Florence, Italy
Internal Medicine, University of Perugia, 06100 Perugia, Italy
Author to whom correspondence should be addressed.
J. Funct. Morphol. Kinesiol. 2018, 3(1), 3;
Received: 10 November 2017 / Revised: 20 December 2017 / Accepted: 23 December 2017 / Published: 27 December 2017
(This article belongs to the Special Issue Tailored Exercise in Patients with Chronic Diseases 2017)
Diabetes mellitus Type 2 (DMT2) carries a high risk of cardiovascular (CV) morbidity and mortality. Physical activity (PA) is widely prescribed for this population. However, detection of the eventual risk level and the potential additional increase through physical exercise are of paramount importance in these patients. A model for predicting absolute risk for coronary artery disease in diabetes has been provided in the investigation by the UKPDS (United Kingdom Prospective Diabetes Study). The present study aims to verify the potential feasibility of the UKPDS calculation in an out-patient context, where patients with DMT2 can be selected for an exercise prescription program. All patients investigated were consecutively enrolled in the study at the time of the first clinical check-up in the outpatient center of the University of Perugia-Internal Medicine Department. A group of 101 Caucasian patients (62 males; 39 females; aged 67 ± 2 years) were studied. In agreement with the UKPDS score, gender, age, ethnicity, Body Mass Index, systolic blood pressure and smoking habits were considered. The global mean cardiovascular risk calculated by the UKPDS risk-engine was 25.8% of a first cardiovascular event within 10 years after the initial observation. Despite an absence of symptoms, the risk was globally high and in agreement with current literature. Conclusion: The data are suggestive of a potential large clinical application of UKPDS risk-engine score in an outpatient context, especially in those asymptomatic DMT2 patients potentially enrolled in a physical activity program. This pilot investigation supports the importance for immediate estimation of cardiovascular risk in DMT2 subjects to implement basic therapeutic strategies such as physical activity. View Full-Text
Keywords: type 2 diabetes; UKPDS score; exercise; cardiovascular risk type 2 diabetes; UKPDS score; exercise; cardiovascular risk
Show Figures

Figure 1

MDPI and ACS Style

Petri, C.; Tantucci, A.; Angeloni, G.; Bomboletti, G.; Mascherini, G.; Bini, V.; De Angelis, M.; Galanti, G.; Stefani, L. Diabetes Type 2 and Physical Activity Program: Potential Application of Risk-Engine UKPDS Score in Out-Patient Context. J. Funct. Morphol. Kinesiol. 2018, 3, 3.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop