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Fused Zinc Target for the Production of Gallium Radioisotopes

1
Life Sciences Division, TRIUMF, Vancouver, BC V6T 2A3, Canada
2
Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, S-171 76 Stockholm, Sweden
*
Author to whom correspondence should be addressed.
Instruments 2019, 3(1), 10; https://doi.org/10.3390/instruments3010010
Received: 17 December 2018 / Revised: 8 January 2019 / Accepted: 24 January 2019 / Published: 1 February 2019
(This article belongs to the Special Issue Instruments and Methods for Cyclotron Produced Radioisotopes)
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Abstract

Gallium-68 is a popular radioisotope for positron emission tomography. To make gallium-68 more accessible, we developed a new solid target for medical cyclotrons. Fused zinc targets promise a new, efficient, and reliable technique without the downsides of other commonly used time-consuming methods for solid target fabrication, such as electroplating and sputtering. We manufactured targets by fusing small pressed zinc pellets into a recess in aluminum backings. Using a simple hotplate, the fusing could be accomplished in less than two minutes. Subsequently, the targets were cooled, polished, and used successfully for test irradiations at Ep = 12.8 MeV and up to 20 µA proton current. View Full-Text
Keywords: PET; medical isotopes; Ga-68; solid target PET; medical isotopes; Ga-68; solid target
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MDPI and ACS Style

Zeisler, S.; Limoges, A.; Kumlin, J.; Siikanen, J.; Hoehr, C. Fused Zinc Target for the Production of Gallium Radioisotopes. Instruments 2019, 3, 10.

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