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Volume 3
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10.3390/mps3010016
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Protocol

Antimicrobial Lock Therapy in Clinical Practice: A Scoping Review Protocol

by
Aniello Alfieri
1,†,
Sveva Di Franco
1,†,
Maria Beatrice Passavanti
1,
Maria Caterina Pace
1,
Agata Stanga
1,
Vittorio Simeon
2,
Paolo Chiodini
2,
Sebastiano Leone
3,
Vettakkara Kandy Muhammed Niyas
4 and
Marco Fiore
1,*
1
Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy
2
Department of Public, Clinical and Preventive Medicine, Medical Statistics Unit, University of Campania Luigi Vanvitelli, 80138 Naples, Italy
3
Division of Infectious Diseases, Department of Internal Medicine, San Giuseppe Moscati Hospital, Contrada Amoretta, 83100 Avellino, Italy
4
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Methods Protoc. 2020, 3(1), 16; https://doi.org/10.3390/mps3010016
Received: 19 December 2019 / Revised: 7 February 2020 / Accepted: 10 February 2020 / Published: 12 February 2020
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Abstract

Our objective is to review the scientific literature on the use of antimicrobial lock therapy (ALT). To achieve this result, our scoping review will address the following seven key questions: (1) Who are the patients who will benefit from this technique? (2) What are the techniques utilized? (3) What are the settings in which the technique is performed? (4) When the technique is performed? (5) Why the technique is performed? (6) How the technique is performed? (7) In how much amount, of such technique performed? This review considers all studies published in full and in peer-reviewed journals, with no restrictions on language, on the year of publication and age of the participants. Both randomized controlled trials and observational studies will be included. This scoping review has been planned on a five-stage framework: 1. Identifying the review question; 2. identifying relevant studies; 3. study selection; 4. charting the data; 5. collating, summarizing, and reporting the results. It is conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines. The databases utilized will include MEDLINE via PubMed, EMBASE and Cochrane Central Register of Controlled Trials and Grey Literature. SCOPING REVIEW REGISTRATION: Open Science Framework https://osf.io/vphwm/. View Full-Text
Keywords: antimicrobial lock therapy; ALT; anti-infective agents; bacteremia; biofilm; central venous catheters; catheter-related bloodstream infection; central-line-associated bloodstream infection; scoping review antimicrobial lock therapy; ALT; anti-infective agents; bacteremia; biofilm; central venous catheters; catheter-related bloodstream infection; central-line-associated bloodstream infection; scoping review
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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MDPI and ACS Style

Alfieri, A.; Di Franco, S.; Passavanti, M.B.; Pace, M.C.; Stanga, A.; Simeon, V.; Chiodini, P.; Leone, S.; Niyas, V.K.M.; Fiore, M. Antimicrobial Lock Therapy in Clinical Practice: A Scoping Review Protocol. Methods Protoc. 2020, 3, 16. https://doi.org/10.3390/mps3010016

AMA Style

Alfieri A, Di Franco S, Passavanti MB, Pace MC, Stanga A, Simeon V, Chiodini P, Leone S, Niyas VKM, Fiore M. Antimicrobial Lock Therapy in Clinical Practice: A Scoping Review Protocol. Methods and Protocols. 2020; 3(1):16. https://doi.org/10.3390/mps3010016

Chicago/Turabian Style

Alfieri, Aniello, Sveva Di Franco, Maria B. Passavanti, Maria C. Pace, Agata Stanga, Vittorio Simeon, Paolo Chiodini, Sebastiano Leone, Vettakkara K.M. Niyas, and Marco Fiore. 2020. "Antimicrobial Lock Therapy in Clinical Practice: A Scoping Review Protocol" Methods and Protocols 3, no. 1: 16. https://doi.org/10.3390/mps3010016

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