Different Ultrasound Shear Wave Elastography Techniques as Novel Imaging-Based Approaches for Quantitative Evaluation of Hepatic Steatosis—Preliminary Findings
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. US Examinations
2.3. Shear-Wave Elastography
2.4. Shear-Wave Dispersion
2.5. Attenuation Imaging Technique
2.6. MRI of the Liver Using Proton Density Fat Fraction (PDFF) Sequences
2.7. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Mean ± SD (Range) | AUC (95% CI) | Sensitivity | Specificity | r | p-Value | Cut-Off Value | |
---|---|---|---|---|---|---|---|
SWE (m/s) | 2.8 ± 0.76 (1.24–4.43) | 0.73 (0.46–0.99) | 75% | 72.7% | 0.27 | >0.05 | 2.5 |
SWE (kPa) | 20.8 ± 16.8. (4.9–62.5) | 0.73 (0.46–0.99) | 75% | 72.7% | 0.27 | 0.001 * | 20.4 |
SWD (m/s/kHz) | 16.5 ± 4.58 (10.5–23.1) | 0.73 (0.35–1) | 75% | 90.9% | 0.55 | 0.034 * | 18.5 |
ATI (dB/cm/MHz) | 0.6 ± 0.12 (0.5–0.8) | 0.53 (0.18 –0.88) | 50% | 54.5% | 0.58 | 0.024 * | 0.59 |
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Platz Batista da Silva, N.; Scharf, G.; Lürken, L.; Verloh, N.; Schleder, S.; Stroszczynski, C.; Jung, E.M.; Haimerl, M. Different Ultrasound Shear Wave Elastography Techniques as Novel Imaging-Based Approaches for Quantitative Evaluation of Hepatic Steatosis—Preliminary Findings. Tomography 2023, 9, 681-692. https://doi.org/10.3390/tomography9020054
Platz Batista da Silva N, Scharf G, Lürken L, Verloh N, Schleder S, Stroszczynski C, Jung EM, Haimerl M. Different Ultrasound Shear Wave Elastography Techniques as Novel Imaging-Based Approaches for Quantitative Evaluation of Hepatic Steatosis—Preliminary Findings. Tomography. 2023; 9(2):681-692. https://doi.org/10.3390/tomography9020054
Chicago/Turabian StylePlatz Batista da Silva, Natascha, Gregor Scharf, Lukas Lürken, Niklas Verloh, Stephan Schleder, Christian Stroszczynski, Ernst Michael Jung, and Michael Haimerl. 2023. "Different Ultrasound Shear Wave Elastography Techniques as Novel Imaging-Based Approaches for Quantitative Evaluation of Hepatic Steatosis—Preliminary Findings" Tomography 9, no. 2: 681-692. https://doi.org/10.3390/tomography9020054