Next Article in Journal
Assessment of Aortoiliac Atherosclerotic Plaque on CT in Prostate Cancer Patients Undergoing Treatment
Next Article in Special Issue
Quantitative Assessment of Airway Changes in Fibrotic Interstitial Lung Abnormality Patients by Chest CT According to Cumulative Cigarette Smoking
Previous Article in Journal
Initial Experience on Hyperpolarized [1-13C]Pyruvate MRI Multicenter Reproducibility—Are Multicenter Trials Feasible?
Article

Ipsilateral Recurrence of DCIS in Relation to Radiomics Features on Contrast Enhanced Breast MRI

1
Department of Radiology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea
2
Division of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin 17035, Korea
3
Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea
*
Author to whom correspondence should be addressed.
Academic Editor: Norbert Hosten
Tomography 2022, 8(2), 596-606; https://doi.org/10.3390/tomography8020049
Received: 29 December 2021 / Revised: 13 February 2022 / Accepted: 25 February 2022 / Published: 1 March 2022
(This article belongs to the Special Issue Quantitative Imaging in Oncology)
The purpose of this retrospective study was to investigate the association between ipsilateral recurrence of ductal carcinoma in situ (DCIS) and radiomics features from DCIS and contralateral normal breast on contrast enhanced breast MR imaging. A total of 163 patients with DCIS who underwent preoperative MR imaging between January 2010 and December 2014 were included (training cohort; n = 117, validation cohort; n = 46). Radiomics features were extracted from whole tumor volume of DCIS on early dynamic T1-subtraction images and from the contralateral normal breast on precontrast T1 and early dynamic T1-subtraction images. After feature selection, a Rad-score was established by LASSO Cox regression model. Performance of Rad-score was evaluated by the receiver operating characteristic (ROC) curve and Kaplan Meier curve with log rank test. The Rad-score was significantly associated with ipsilateral recurrence free survival (RFS). The low-risk group with a low Rad-score showed higher ipsilateral RFS than the high-risk group with a high Rad-score in both training and validation cohorts (p < 0.01). The Rad-score based on radiomics features from DCIS and contralateral normal breast on breast MR imaging showed the potential for prediction of ipsilateral RFS of DCIS. View Full-Text
Keywords: breast cancer; quantitative imaging; magnetic resonance imaging breast cancer; quantitative imaging; magnetic resonance imaging
Show Figures

Figure 1

MDPI and ACS Style

Park, G.E.; Kim, S.H.; Lee, E.B.; Nam, Y.; Sung, W. Ipsilateral Recurrence of DCIS in Relation to Radiomics Features on Contrast Enhanced Breast MRI. Tomography 2022, 8, 596-606. https://doi.org/10.3390/tomography8020049

AMA Style

Park GE, Kim SH, Lee EB, Nam Y, Sung W. Ipsilateral Recurrence of DCIS in Relation to Radiomics Features on Contrast Enhanced Breast MRI. Tomography. 2022; 8(2):596-606. https://doi.org/10.3390/tomography8020049

Chicago/Turabian Style

Park, Ga E., Sung H. Kim, Eun B. Lee, Yoonho Nam, and Wonmo Sung. 2022. "Ipsilateral Recurrence of DCIS in Relation to Radiomics Features on Contrast Enhanced Breast MRI" Tomography 8, no. 2: 596-606. https://doi.org/10.3390/tomography8020049

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop