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Hydrogels Based on Dynamic Covalent and Non Covalent Bonds: A Chemistry Perspective

Department of Chemical Engineering, Engineering and Technology Institute Groningen (ENTEG), University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
Department of Chemical Engineering, Parahyangan Catholic University, Ciumbuleuit 94, Bandung 40141, West Java, Indonesia
Author to whom correspondence should be addressed.
Received: 23 February 2018 / Revised: 4 March 2018 / Accepted: 5 March 2018 / Published: 8 March 2018
(This article belongs to the Special Issue Hydrogels Based on Dynamic Covalent Chemistry)
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Hydrogels based on reversible covalent bonds represent an attractive topic for research at both academic and industrial level. While the concept of reversible covalent bonds dates back a few decades, novel developments continue to appear in the general research area of gels and especially hydrogels. The reversible character of the bonds, when translated at the general level of the polymeric network, allows reversible interaction with substrates as well as responsiveness to variety of external stimuli (e.g., self-healing). These represent crucial characteristics in applications such as drug delivery and, more generally, in the biomedical world. Furthermore, the several possible choices that can be made in terms of reversible interactions generate an almost endless number of possibilities in terms of final product structure and properties. In the present work, we aim at reviewing the latest developments in this field (i.e., the last five years) by focusing on the chemistry of the systems at hand. As such, this should allow molecular designers to develop a toolbox for the synthesis of new systems with tailored properties for a given application. View Full-Text
Keywords: hydrogels; dynamic covalent bonds; reversible polymeric network hydrogels; dynamic covalent bonds; reversible polymeric network

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Picchioni, F.; Muljana, H. Hydrogels Based on Dynamic Covalent and Non Covalent Bonds: A Chemistry Perspective. Gels 2018, 4, 21.

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