Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020)

Dai, Quan; Zhang, Fa-Lei; Feng, Tao

doi:10.3390/jof7121026

Open AccessReview

Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020)

by

Quan Dai

^†,

Fa-Lei Zhang

^†

and

Tao Feng

^*

School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this paper.

J. Fungi 2021, 7(12), 1026; https://doi.org/10.3390/jof7121026

Submission received: 14 November 2021 / Revised: 28 November 2021 / Accepted: 28 November 2021 / Published: 30 November 2021

(This article belongs to the Special Issue Secondary Metabolites from Fungi—in Honour of Prof. Dr. Ji-Kai Liu's 60th Birthday)

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Abstract

Fungi are widely distributed in the terrestrial environment, freshwater, and marine habitat. Only approximately 100,000 of these have been classified although there are about 5.1 million characteristic fungi all over the world. These eukaryotic microbes produce specialized metabolites and participate in a variety of ecological functions, such as quorum detection, chemical defense, allelopathy, and maintenance of symbiosis. Fungi therefore remain an important resource for the screening and discovery of biologically active natural products. Sesquiterpenoids are arguably the richest natural products from plants and micro-organisms. The rearrangement of the 15 high-ductility carbons gave rise to a large number of different skeletons. At the same time, abundant structural variations lead to a diversification of biological activity. This review examines the isolation, structural determination, bioactivities, and synthesis of sesquiterpenoids that were specially produced by fungi over the past five years (2015–2020).

Keywords: sesquiterpenoids; fungus; structures; structural diversity; biological activity; synthesis

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MDPI and ACS Style

Dai, Q.; Zhang, F.-L.; Feng, T. Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020). J. Fungi 2021, 7, 1026. https://doi.org/10.3390/jof7121026

AMA Style

Dai Q, Zhang F-L, Feng T. Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020). Journal of Fungi. 2021; 7(12):1026. https://doi.org/10.3390/jof7121026

Chicago/Turabian Style

Dai, Quan, Fa-Lei Zhang, and Tao Feng. 2021. "Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020)" Journal of Fungi 7, no. 12: 1026. https://doi.org/10.3390/jof7121026

APA Style

Dai, Q., Zhang, F.-L., & Feng, T. (2021). Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020). Journal of Fungi, 7(12), 1026. https://doi.org/10.3390/jof7121026

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020)

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