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Review

Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms

by
Jing Luo
1,2,†,
Kumar Ganesan
1,3,† and
Baojun Xu
1,*
1
Food Science and Technology Programme, Department of Life Sciences, BNU-HKBU United International College, Zhuhai 519087, China
2
TUMCREATE, 1 Create Way, Singapore 138602, Singapore
3
School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
J. Fungi 2024, 10(3), 215; https://doi.org/10.3390/jof10030215
Submission received: 22 February 2024 / Revised: 10 March 2024 / Accepted: 12 March 2024 / Published: 14 March 2024
(This article belongs to the Special Issue Fungal Biotechnology and Application 2.0)

Abstract

Aging is a complex biological process that is influenced by both intrinsic and extrinsic factors. Recently, it has been discovered that reactive oxygen species can accelerate the aging process, leading to an increased incidence of age-related diseases that are characteristic of aging. This review aims to discuss the potential of mushrooms as a dietary intervention for anti-aging, focusing on their nutritional perspective. Mushrooms contain various bioactive compounds, including carbohydrates, bioactive proteins, fungal lipids, and phenolic compounds. These compounds have shown promising effectiveness in combating skin aging and age-related diseases. In vitro and in vivo studies have demonstrated that treatments with mushrooms or their extracts can significantly extend lifespan and improve health span. Furthermore, studies have aimed to elucidate the precise cellular and molecular mechanisms of action and the structure–activity relationship of mushroom bioactive compounds. These findings provide a strong basis for further research, including human clinical trials and nutritional investigations, to explore the potential benefits of mushrooms in real-life anti-aging practices. By exploring the anti-aging effects of mushrooms, this review aims to provide valuable insights that can contribute to the development of broader strategies for healthy aging.
Keywords: Mushrooms; anti-aging; age-related disease; cellular mechanisms; bioactive compounds Mushrooms; anti-aging; age-related disease; cellular mechanisms; bioactive compounds

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MDPI and ACS Style

Luo, J.; Ganesan, K.; Xu, B. Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms. J. Fungi 2024, 10, 215. https://doi.org/10.3390/jof10030215

AMA Style

Luo J, Ganesan K, Xu B. Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms. Journal of Fungi. 2024; 10(3):215. https://doi.org/10.3390/jof10030215

Chicago/Turabian Style

Luo, Jing, Kumar Ganesan, and Baojun Xu. 2024. "Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms" Journal of Fungi 10, no. 3: 215. https://doi.org/10.3390/jof10030215

APA Style

Luo, J., Ganesan, K., & Xu, B. (2024). Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms. Journal of Fungi, 10(3), 215. https://doi.org/10.3390/jof10030215

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