Next Article in Journal
Open Coronary Endarterectomy of Left Anterior Descending Artery—Case Report and Review of Literature
Previous Article in Journal
Salvage of Cardiac Implantable Electronic Device Pocket Infection with Skin Erosion in Frail 92-Year-Old
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCDD
Volume 9
Issue 3
10.3390/jcdd9030082
jcdd-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up

by
Pablo Juan-Salvadores
1,2,*,
Víctor Alfonso Jiménez Díaz
1,2,3,
Cristina Iglesia Carreño
4,
Alba Guitián González
4,
Cesar Veiga
2,
Cristina Martínez Reglero
5,
José Antonio Baz Alonso
2,3,
Francisco Caamaño Isorna
6,7 and
Andrés Iñiguez Romo
2,4
1
Cardiovascular Research Unit, Cardiology Department, Hospital Alvaro Cunqueiro, University Hospital of Vigo, 36213 Vigo, Spain
2
Cardiovascular Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), Servizo Galego de Saude, Universidade de Vigo, 36213 Vigo, Spain
3
Interventional Cardiology Unit, Cardiology Department, Hospital Álvaro Cunqueiro, University Hospital of Vigo, 36213 Vigo, Spain
4
Cardiology Department, Hospital Álvaro Cunqueiro, University Hospital of Vigo, 36213 Vigo, Spain
5
Methodology and Statistics Unit, Galicia Sur Health Research Institute (IIS Galicia Sur), Servizo Galego de Saude, Universidade de Vigo, 36213 Vigo, Spain
6
Department of Preventive Medicine, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain
7
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP), 15782 Santiago de Compostela, Spain
*
Author to whom correspondence should be addressed.
J. Cardiovasc. Dev. Dis. 2022, 9(3), 82; https://doi.org/10.3390/jcdd9030082
Submission received: 3 February 2022 / Revised: 5 March 2022 / Accepted: 9 March 2022 / Published: 11 March 2022
(This article belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)
Browse Figures
Versions Notes

Abstract

Coronary artery disease (CAD) is a common chronic condition in the elderly. However, the earlier CAD begins, the stronger its impact on lifestyle and costs of health and social care. The present study analyzes clinical and angiographic features and the outcome of very young patients undergoing coronary angiography due to suspected CAD, including a nested case-control study of ≤40-year-old patients referred for coronary angiography. Patients were divided into two groups: cases with significant angiographic stenosis, and controls with non-significant stenosis. Of the 19,321 coronary angiographies performed in our center in a period of 10 years, 504 (2.6%) were in patients ≤40 years. The most common cardiovascular risk factors for significant CAD were smoking (OR 2.96; 95% CI 1.65–5.37), dyslipidemia (OR 2.18; 95% CI 1.27–3.82), and family history of CAD (OR 1.95; 95% CI 1.05–3.75). The incidence of major adverse cardiovascular events (MACE) at follow-up was significantly higher in the cases compared to controls (HR 2.71; 95% CI 1.44–5.11). Three conventional coronary risk factors were directly related to the early signs of CAD. MACE in the long-term follow-up is associated to dyslipidaemia and hypertriglyceridemia. Focusing efforts for the adequate control of CAD in young patients is a priority given the high socio-medical cost that this disease entails to society.
Keywords: coronary artery disease; risk factors; young; percutaneous coronary intervention; clinical epidemiology; acute coronary syndrome; stable angina coronary artery disease; risk factors; young; percutaneous coronary intervention; clinical epidemiology; acute coronary syndrome; stable angina

Share and Cite

MDPI and ACS Style

Juan-Salvadores, P.; Jiménez Díaz, V.A.; Iglesia Carreño, C.; Guitián González, A.; Veiga, C.; Martínez Reglero, C.; Baz Alonso, J.A.; Caamaño Isorna, F.; Iñiguez Romo, A. Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up. J. Cardiovasc. Dev. Dis. 2022, 9, 82. https://doi.org/10.3390/jcdd9030082

AMA Style

Juan-Salvadores P, Jiménez Díaz VA, Iglesia Carreño C, Guitián González A, Veiga C, Martínez Reglero C, Baz Alonso JA, Caamaño Isorna F, Iñiguez Romo A. Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up. Journal of Cardiovascular Development and Disease. 2022; 9(3):82. https://doi.org/10.3390/jcdd9030082

Chicago/Turabian Style

Juan-Salvadores, Pablo, Víctor Alfonso Jiménez Díaz, Cristina Iglesia Carreño, Alba Guitián González, Cesar Veiga, Cristina Martínez Reglero, José Antonio Baz Alonso, Francisco Caamaño Isorna, and Andrés Iñiguez Romo. 2022. "Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up" Journal of Cardiovascular Development and Disease 9, no. 3: 82. https://doi.org/10.3390/jcdd9030082

APA Style

Juan-Salvadores, P., Jiménez Díaz, V. A., Iglesia Carreño, C., Guitián González, A., Veiga, C., Martínez Reglero, C., Baz Alonso, J. A., Caamaño Isorna, F., & Iñiguez Romo, A. (2022). Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up. Journal of Cardiovascular Development and Disease, 9(3), 82. https://doi.org/10.3390/jcdd9030082

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop