Pilot Study: Assessing the Expression of Serum Lactate Dehydrogenase and Peripheral Leukocyte Ratios in Canine Oral Malignant Melanoma
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Patient Selection Criteria
2.2. Evaluation of Serum LDH
2.3. Evaluation of NLR and LMR
2.4. Statistical Analysis
3. Results
3.1. Patient Population
3.2. Serum LDH Values between Groups
3.3. NLR and LMR between Groups
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Haematological Parameter | Reference Values |
---|---|
White blood cell count (×109/L) | 6.0–15.0 |
Neutrophil count (×109/L) | 3.6–12.0 |
Lymphocyte count (×109/L) | 0.7–4.8 |
Monocyte count (×109/L) | 0–1.5 |
Patient | Age (Years) | Breed | Sex | Group | Tumour Location | LN Metastasis | Lung Metastasis | LN Assessment | Chest Assessment | LDH (U/L) | NLR | LMR |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 11 | Cross breed | FE | Metastatic | Gingival | Yes | No | FNA | 3-view chest X-ray | 442 | 2.46 | 4.00 |
2 | 12 | Labrador | ME | Metastatic | Gingival | Yes | No | FNA | CT | 611 | 7.73 | 3.67 |
3 | 9 | Labrador | FN | Metastatic | Lingual | Yes | Yes | FNA | CT | 198 | 9.11 | 1.50 |
4 | 10 | Cocker spaniel | FN | Metastatic | Gingival | Yes | No | FNA | CT | 2032 | 5.37 | 4.67 |
5 | 10 | Cocker spaniel | FN | Metastatic | Gingival | Yes | No | Histopathology | CT | 885 | 7.50 | 1.46 |
6 | 13 | Tibetan terrier | ME | Metastatic | Gingival | Yes | No | FNA | CT | 1.94 | 5.33 | |
7 | 8 | Golden retriever | ME | Metastatic | Gingival | Yes | No | Histopathology | CT | 3.43 | 4.20 | |
8 | 10 | Golden retriever | FN | Metastatic | Gingival | Yes | No | Histopathology | CT | 3.04 | 7.67 | |
9 | 9 | Red setter | ME | Metastatic | Gingival | Yes | No | Histopathology | 3-view chest X-ray | 6.15 | 2.17 | |
10 | 5 | Labrador | MN | Non-metastatic | Gingival | No | No | Histopathology | 3-view chest X-ray | 1612 | 3.40 | 5.00 |
11 | 8 | Labrador | ME | Non-metastatic | Gingival | No | No | Histopathology | 3-view chest X-ray | 1762 | ||
12 | 11 | Labrador | FN | Non-metastatic | Gingival | No | No | Histopathology | CT | 327 | 4.29 | 2.43 |
13 | 13 | Border terrier | FN | Non-metastatic | Gingival | No | No | Histopathology | CT | 7.90 | 1.11 | |
14 | 12 | Bearded collie | MN | Non-metastatic | Gingival | No | No | Histopathology | 3-view chest X-ray | 11.57 | 1.17 | |
15 | 12 | Cocker spaniel | FN | Non-metastatic | Gingival | No | No | Histopathology | 3-view chest X-ray | 1.14 | 5.25 | |
16 | 1 | Hungarian vizsla | MN | Control | 505 | |||||||
17 | 10 | Cross breed | FE | Control | 294 | |||||||
18 | 11 | Labrador | MN | Control | 488 | |||||||
19 | 8 | Spaniel (unspecified) | FE | Control | 228 | |||||||
20 | 2 | Golden retriever | FN | Control | 278 | |||||||
21 | 4 | Goldenretriever | ME | Control | 405 | |||||||
22 | 3 | Cocker spaniel | FN | Control | 303 | |||||||
23 | 11 | Labrador | FN | Control | 1368 | |||||||
24 | 1 | Cocker spaniel | FN | Control | 235 | |||||||
25 | 2 | Golden retriever | MN | Control | 290 |
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Murray, B.; Blacklock, K.L.B. Pilot Study: Assessing the Expression of Serum Lactate Dehydrogenase and Peripheral Leukocyte Ratios in Canine Oral Malignant Melanoma. Vet. Sci. 2022, 9, 421. https://doi.org/10.3390/vetsci9080421
Murray B, Blacklock KLB. Pilot Study: Assessing the Expression of Serum Lactate Dehydrogenase and Peripheral Leukocyte Ratios in Canine Oral Malignant Melanoma. Veterinary Sciences. 2022; 9(8):421. https://doi.org/10.3390/vetsci9080421
Chicago/Turabian StyleMurray, Ben, and Kelly L. Bowlt Blacklock. 2022. "Pilot Study: Assessing the Expression of Serum Lactate Dehydrogenase and Peripheral Leukocyte Ratios in Canine Oral Malignant Melanoma" Veterinary Sciences 9, no. 8: 421. https://doi.org/10.3390/vetsci9080421
APA StyleMurray, B., & Blacklock, K. L. B. (2022). Pilot Study: Assessing the Expression of Serum Lactate Dehydrogenase and Peripheral Leukocyte Ratios in Canine Oral Malignant Melanoma. Veterinary Sciences, 9(8), 421. https://doi.org/10.3390/vetsci9080421