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41 Cases of Treatment of Cranial Cruciate Ligament Rupture with Porous TTA: Three Years of Follow Up

Department of Emergencies and Organ Transplantation (DETO), University of Bari, Aldo Moro, 70010 Bari, Italy
PHD Course of Transplantation of Tissue and Organs and Cell Therapy (DETO) University of Bari, Aldo Moro, 70126 Bari, Italy
Istituto Tecnologico de Canaria (ITC), Canary Islands, 35003 Las Palmas, Spain
Center for Biomedical Research in Network, Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Carlos III Health Institute, 28029 Madrid, Spain
Departamento de Biología Celular, Genética y Fisiología, IBIMA-Universidad de Málaga, Facultad de Ciencias, Campus de Teatinos, 29071 Málaga, Spain
PHD Course of Health and Veterinary Experimental Sciences, University of Perugia, 06123 Perugia, Italy
Author to whom correspondence should be addressed.
Vet. Sci. 2019, 6(1), 18;
Received: 21 December 2018 / Revised: 6 February 2019 / Accepted: 15 February 2019 / Published: 20 February 2019
(This article belongs to the Special Issue Italian Society of the Veterinary Sciences SISVet 2018)
PDF [4824 KB, uploaded 20 February 2019]


Tibial Tuberosity Advancement (TTA) is a surgical technique based on a linear osteotomy that determines a cranial advancement of the tibial tuberosity in patients suffering from cranial cruciate ligament rupture (CCL). The aim is to neutralize the cranial tibial thrust (CTT) and to reach a 90° angle between the patellar tendon and the tibial plateau with a physiological knee extension of 135°. In our study, a Ti6AI4V ELI (Titanium Aluminium Vanadium) titanium scaffold for the Porous TTA, with excellent properties of osteointegration and osteoconduction when subjected to cyclic loading has been adopted. Based on the previous scientific work on an ovine model, the use of this type of porous scaffolds has subverted the previous models. Scaffold production technology is based on direct mechanical manufacturing called Electron Beam Melting (EBM). For this study, 41 dogs, different breeds, medium-large size, weighing between 10 and 80 kg, aged between 1 and 13 years, were enrolled. The inclusion criteria were based on clinical evaluations (different gaits), drawer test and tibial compression, LOAD score (Liverpool Osteoarthritis in Dogs questionnaire), radiographic diagnosis in sedation with a 135° positioning of the joint and baropodometric investigations (Stance Analyzer). The results show that Porous TTA is an excellent method for functional recovery of the knee joint following the partial and total rupture of the CCL. View Full-Text
Keywords: tibial tuberosity advancement; titanium porous cage; dogs tibial tuberosity advancement; titanium porous cage; dogs

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Trisciuzzi, R.; Fracassi, L.; Martin, H.A.; Monopoli Forleo, D.; Amat, D.; Santos-Ruiz, L.; De Palma, E.; Crovace, A.M. 41 Cases of Treatment of Cranial Cruciate Ligament Rupture with Porous TTA: Three Years of Follow Up. Vet. Sci. 2019, 6, 18.

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