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Review

Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review

by
Xiao Meng
1,
Jing Zhou
2,
Cai-Ning Zhao
3,
Ren-You Gan
4,* and
Hua-Bin Li
1
1
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
2
School of Public Health, Hainan Medical University, Haikou 571199, China
3
Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China
4
Research Center for Plants and Human Health, Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu 610213, China
*
Author to whom correspondence should be addressed.
Foods 2020, 9(3), 340; https://doi.org/10.3390/foods9030340
Submission received: 5 February 2020 / Revised: 10 March 2020 / Accepted: 12 March 2020 / Published: 14 March 2020
(This article belongs to the Special Issue Biological Activities of Plant Food Components: Implications in Human Health)
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Abstract

Resveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protective effects, therefore, can protect against diverse chronic diseases, such as cardiovascular diseases (CVDs), cancer, liver diseases, obesity, diabetes, Alzheimer’s disease, and Parkinson’s disease. This review summarizes the main findings of resveratrol-related health benefits in recent epidemiological surveys, experimental studies, and clinical trials, highlighting its related molecular mechanisms. Resveratrol, therefore, has been regarded as a potent candidate for the development of nutraceuticals and pharmaceuticals to prevent and treat certain chronic diseases.
Keywords: resveratrol; bioactivities; anticancer; anti-obesity; antidiabetes; molecular mechanisms resveratrol; bioactivities; anticancer; anti-obesity; antidiabetes; molecular mechanisms

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MDPI and ACS Style

Meng, X.; Zhou, J.; Zhao, C.-N.; Gan, R.-Y.; Li, H.-B. Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review. Foods 2020, 9, 340. https://doi.org/10.3390/foods9030340

AMA Style

Meng X, Zhou J, Zhao C-N, Gan R-Y, Li H-B. Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review. Foods. 2020; 9(3):340. https://doi.org/10.3390/foods9030340

Chicago/Turabian Style

Meng, Xiao, Jing Zhou, Cai-Ning Zhao, Ren-You Gan, and Hua-Bin Li. 2020. "Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review" Foods 9, no. 3: 340. https://doi.org/10.3390/foods9030340

APA Style

Meng, X., Zhou, J., Zhao, C.-N., Gan, R.-Y., & Li, H.-B. (2020). Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review. Foods, 9(3), 340. https://doi.org/10.3390/foods9030340

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