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Review

Static Guided Endodontics in Primary Endodontic Treatment of Anterior Teeth: A Narrative Review

by
Monika Kuczmaja
,
Wiesława Puchalska
and
Agata Żółtowska
*
Department of Conservative Dentistry, Faculty of Medicine, Medical University of Gdańsk, 80-210 Gdańsk, Poland
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Dent. J. 2026, 14(4), 195; https://doi.org/10.3390/dj14040195
Submission received: 22 January 2026 / Revised: 15 February 2026 / Accepted: 20 March 2026 / Published: 26 March 2026
(This article belongs to the Special Issue State of the Art in Oral Radiology)

Abstract

Background: Guided endodontics (GE), introduced in 2016, is an innovative approach aimed at addressing the challenges faced in endodontic treatment, particularly in cases of pulp canal obliteration (PCO). Objectives: This narrative review aims to assess the efficacy and application of static guided endodontics to facilitate minimally invasive access to difficult-to-locate root canals during primary endodontic treatment of incisors and canines. Method: A search strategy of the literature was performed on PubMed until 18 November 2025. The review synthesizes findings from 28 studies, focusing on recent advancements, procedural planning, and clinical outcomes related to GE. Results: Key findings indicate that GE may improve the ability to locate and treat calcified canals, reduce complications associated with traditional methods. Radiographic assessments and clinical indicators demonstrate favorable short- to medium-term outcomes; however, there is an absence of standardized protocols for long-term follow-up. Conclusions: Recommendations for future research include the establishment of unified technical guidelines to enhance consistency and comparability of results across clinical settings. Overall, guided endodontics represents a promising advancement in improving the success of root canal therapy while preserving natural dentition. The primary goal of this article is to update the literature review on static guided endodontics in anterior teeth during primary endodontics.

1. Introduction

Endodontic treatment of teeth with completely or partially obliterated root canals presents significant challenges for clinicians. This is due to the increased risk of perforation, difficulty in locating the canal and a higher rate of treatment failure when conventional techniques are used. Locating calcified or obliterated canals can be very time-consuming and technically demanding. It is often associated with a greater likelihood of perforations and instrument fractures [1,2]. These complications can further complicate the procedure and potentially compromise the structural integrity of the tooth [3]. Despite these difficulties, it remains worthwhile to attempt root canal therapy rather than extracting the tooth. Preserving natural teeth helps maintain function, aesthetics, and overall oral health, and can also prevent additional oral ecosystem complications. The oral cavity is the start of digestion and affects speech, function, health, and appearance, with tooth loss impairing self-esteem and social interactions [4]. Tooth loss due to caries or pulp issues disrupts the oral ecosystem, causing localized problems and issues like TMJ pain [5], headaches, and muscle discomfort [6].
A critical factor contributing to such endodontic treatment challenges is pulp canal obliteration (PCO). Dental pulp is the connective tissue which contains different type of cells—odontoblasts, fibroblasts, mesenchymal stem cells, nerve fibers and vessels [7,8]. The structural relationship between dental pulp and dentin is known as the “dentin—pulp complex” [7]. Dentin synthesis and apposition along dental pulp cavity walls occur during the life of a vital tooth and depend on the activity of specialized cell odontoblasts. The primary dentin is produced during tooth development till the apical foramen is closed [9]. The secondary dentin is produced along all pulp cavity walls throughout life and is a physiological aging process [7,9]. The tertiary dentin is deposited on secondary dentin as a response to pathological stimuli such as caries, traumatic injuries, or orthodontic therapy. That process leads to rapid obliteration of the pulp cavity. The tertiary dentin can be divided into reactionary and reparative, depending on the degree of stimuli [7,9]. The pulp canal obliteration (PCO) is defined as a deposition of hard tissues in the root canal space, most often after dental trauma, which leads to reduction in canal diameter [1,2]. The precise mechanism of PCO is still unclear [1,9]. Accelerated apposition of dentin in PCO is possibly related to revascularization and/or reinnervation of the whole pulp or parts of the pulp after reduced blood flow in pulp vessels due to traumatic dental injury (TDI). Differences in patterns of neural and vessels repair can lead to losing control of sympathetic nerve stimulation over the secretory activity of odontoblasts. That results in rapid deposition of dentin. Inhibitory control of odontoblastic secretion can be reinstituted after pulp revascularization is finished—resulting in partial PCO [9,10]. PCO can occur as a response to different stimuli—for example in teeth after dental trauma [1,9], after orthodontic treatment [11], or in patients on long-term glucocorticosteroids [12]. There are reports suggesting that systemic diseases such as thyroid disorders, hypertension, and diabetes may be linked to pulp canal obliteration (PCO). Hormonal changes and metabolic alterations associated with these conditions can affect dental health, leading to structural changes in teeth and contributing to the occurrence of PCO. Further studies are needed to understand these relationships better and their impact on endodontic treatment [13]. According to Su et al. (2023) [14], isolated dentin defects like Dentin Dysplasia Type I (DD-1) and Dentinogenesis Imperfecta (DI) are correlated with Pulp Canal Obliteration (PCO), with these conditions linked to mutations in the DSPP gene. Moreover, several systemic diseases associated with PCO were identified, including Osteogenesis Imperfecta (OI), Hypophosphatemic Rickets, Ehlers-Danlos Syndrome (EDS), and Schimke Immuno-Osteodysplastic Dysplasia (SIOD), which may be associated with specific changes in tooth structure that lead to pulp canal obliteration [14]. Clinical symptoms of PCO may be crown discoloration (darker or yellowish) and lower or negative response to pulp sensibility tests, although the process of calcification is usually asymptomatic [1,3]. Radiographically, PCO can be partial—when the chamber is not detectable, but part of root canal is visible, or when both chamber and canal are hardly or not detectable [2]. The pulp tests express only conductivity of pulp nerve fibers—not pulp vascular supply. The radiographs reveal the result of osteoclastic/osteoblastic activity in the root or bone, not any other pathological or healing event in process in the pulp [10]. The pulp necrosis in teeth with PCO varies from 1 to 27% but is considered low [1]. Thus, most studies suggest that teeth with PCO should be monitored clinically and radiographically. The root canal treatment should be initiated when periapical disease or clinical symptoms occur. PCO is a challenge during endodontic treatment even for dentists specializing in endodontic treatment [1,3].
In response to the challenges posed by pulp canal obliteration (PCO), guided endodontics (GE) was introduced as a pioneering approach. It was first presented by Krastl et al. in 2016 [15] as a novel treatment strategy specifically designed to address the difficulties associated with treating teeth affected by PCO [15]. The aim of guided endodontics is to achieve minimally invasive access for root canals preparation [15] or endodontic microsurgery [16]. The concept is based on the principle of guided surgery used to reach proper implant placement [15,17,18]. A virtual treatment plan in implantology is now a reality and common procedure. Surgical guides facilitate the insertion of dental implants into an ideal position [19,20]. Today, guided endodontics is used in multiple treatments, such as locating root canals in teeth with pulp canal obliteration [15] and locating canal paths in teeth with previous endodontic failure—for example via falsa, deviation [3], removing glass fiber posts [21], treating teeth with complicated anatomy, e.x. dens invaginatus [22], or microsurgical endodontics [23]. Guided endodontics can be divided into static guided endodontics (use of a template) and dynamic guided endodontics, where markers are positioned in patient’s mouth and a stereo camera is connected to the dynamic navigation system [24,25]. Cone-beam computed tomography (CBCT) is the basis of digital planning in guided endodontics, both static and dynamic [17].
The entire process of static guided endodontics can be divided into two main parts:
(1)
A planning and laboratory part—digital planning and laboratory production of endodontics guide
(2)
A clinical part—endodontics treatment with the use of endodontic guide [17].
The first step of planning demands a CBCT and patient’s arch digital registration. To visualize calcified root canals, a CBCT with the smallest field of view and high resolution is required. The CBCT scan is stored in a Digital Imaging and Communication (DICOM) format. Digital arch registration can be performed directly by an intraoral scanner or by taking an impression and scanning the dental model in the dental laboratory. The digital file of arch registration is stored in Standard Tesselation Language (STL) format. For the virtual planning, the digital planning software is required. Digital software synchronizes and overlays the DICOM file from CBCT with the STL file of the patient’s arch model. The CBCT image should allow to localize the visible part of the root canal. The virtual image of the drill is positioned so that the tip of the drill reaches the visible part of the root canal. Once the drill and sleeve positions are planned, the virtual template is designed. The guide should cover the labial and palatal surfaces of the adjacent teeth; the high of the sleeve and the diameter of the sleeve hole should be adapted to the drill length and diameter. The STL file of the temple is exported from planning software and processed in the slicer software, which allows to prepare the file for 3D printing. The clinical steps start with checking the endodontics guide fitting and stability. The enamel is removed with the diamond bur. A mark placed through the template can indicate the region of the endodontic access. Then, the specific bur is inserted through the prepared hole and moved slowly in depth with pumping movements. The drill is cleaned regularly of debris and the root canal is irrigated. After each few millimeters gain in the depth, the hand file is used to check if the canal can be negotiated. The procedure is continued till the bur is stopped by the sleeve dimension. If the canal is located, the conventional root canal treatment can be performed [15,17,18,24,25,26].
The entire workflow is presented in Table 1.

2. Materials and Methods

A search strategy of the literature was performed on PubMed until 18 November 2025 with the following keywords: “Guided Endodontic” OR “Guided Endodontics” OR “Guided Endodontic Access” OR “Guided Endodontic Treatment”. No year restriction nor language restriction were applied. The abstracts were manually reviewed by two independent researchers and articles with exclusion criteria were screened out. Later, full-text evaluation was performed to complete the list of articles.
Inclusion criteria were: specific keywords, the case reports which involve primary endodontic treatments of incisors and canines, and in vivo studies.
Exclusion criteria were: articles in other languages than English, reviews, articles focusing on premolars and molars, in vitro studies, articles on guided endodontics microsurgery/surgery, articles on dynamic guided endodontics, augmented reality, PriciGuide, case reports describing the use of endodontic navigation for endodontic retreatment, removal of fractured instruments, glass fiber post removal or treatment of dens invaginatus, experts’ opinions/comments/responses to letters, and articles that do not focus solely on guided endodontics (GE).
The PRISMA flow chart of the study selection is presented in Figure 1.

3. Results

Based on the literature review, 221 publications were initially identified; 203 articles were selected for full-text review. Subsequently, 175 articles were excluded, leaving a final set of publications for analysis. For the study, case reports and original studies related to guided endodontics (GE) and its applications on anterior teeth, such as incisors and canines, published from 2016 onwards, were focused upon. The selected articles, which address primary indications and techniques of guided endodontic procedures, are summarized in Table 2. These publications encompass a range of approaches and outcomes, providing a comprehensive overview of recent advancements in the field.
Introduction and Objectives of Guided Endodontics Therapy
From the 28 selected studies 27 are case reports/case series studies and one [49] is an observational study in 50 patients. The diagnoses of treated teeth were mainly described as Apical Periodontitis (AAP, SAP, AAA, CAA) or pulp necrosis. All selected studies reported PCO as a main problem and the reason why guided endodontics was applied; additional problems were reported in two studies: root fracture [27] and previous iatrogenic deviation [28].
First Visit and Imaging Diagnostics
The clinical and digital protocols were similar in all studies: the CBCT as the radiographic examination, intraoral scans/plaster casts scanning, and exporting both files to the scanning software and matching them. The CBCT machines used in the studies varied widely. The voxel size is specified in 13 studies and differs from 0.075 mm to 0.5 mm. The CBCT images allowed to visualize part of the root canals, though the planned length of the drill path is not always specified. The conventional intraoral impressions with a following plaster cast scanning were performed in five studies [29,30,31,32,33]; in 23 studies intraoral scans were taken [27,28,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53].
Procedure Planning and Design
The majority of studies utilized various software solutions for guided endodontic planning, with common tools including BlueSkyPlan [27,35,40,43,48,52], SimPlant [28,33,47,50] and 3Shape [39,46,53]. In addition, endodontic guides were predominantly fabricated using a range of 3D printing technologies, the most commonly used being the Objet Eden 260 V [28,33,50,51] and materials, mainly resins, with some variations in the use of metal or sleeve-less designs.
Clinical Practice: Procedure Execution
A review of current research indicates that various types of drills were employed during clinical procedures for guided endodontics to obtain endodontic access to the patent part of canal. The most commonly used drill was the Munce Discovery Bur (CJM Engineering, Santa Barbara, CA, USA) [27,31,35,36,40,41,52]. Several other drills were utilized: Tivoly drills [34], Gates Glidden drills [42], and EG5 drills [29]. Most studies reported using a drill speed of around 10,000 rpm [31,33,34,38,43,44,47,51], though some employed higher or lower speeds depending on the bur type or conditions, while many did not specify the drill speed at all [27,35,36,37,39,40,41,42,45,46,48,52,53]. The time needed to locate the obliterated canal with GE is reported only in a few studies and varies from approximately 5 to 15 min [29,32,42,48], while many did not specify the exact time.
Follow-up and Outcome Evaluation
Follow-up periods ranged from 24 h [45] to up to 3 years [29]. In some articles the follow-up periods are very short—days or weeks [28,33,38,45]. The short follow-up periods were not enough to evaluate the radiological outcome. A 6-month follow-up period was reported in five studies [30,31,34,36,41], a one-year period was reported in six studies [27,28,35,42,43,50], an 18-month period was reported in four articles [34,40,42,53], and 2-year and 3-year periods were reported in two cases [29,37]. Some studies did not report any follow-up evaluation [32,46,48,49,51,53].
The clinical outcomes connected with pain were mainly described as “asymptomatic” or “no pain” [28,29,31,33,36,39,40,41,42,43,44,50,52]. Most studies reported teeth as asymptomatic, with normal function and radiographic evidence of healing [27,29,30,31,34,35,36,37,39,40,41,43,44,47,50,52], though several lacked detailed descriptions of healing outcomes [28,32,33,38,42,45,46,48,49,51,53].
The clinical and radiological follow-ups are summarized in Table 3.

4. Discussion

The main aim of root canal treatment is chemical cleaning and disinfection, which can be performed only when root canals are located, negotiated and mechanically prepared. Missed canals are highly connected with later apical periodontitis [54,55]. The PCO—confirmed in radiograph and CBCT—was the reason for using GE in all reviewed studies. The application of GE in all described cases was described as clinically successful—the obliterated root canals were located, the work length was reached and canals were obturated. The CBCT plays a crucial role in preoperative planning of calcified canals treatment. For the diagnosis of endodontic problems, the small FOV (Field of View) CBCT scans are recommended. In the small FOV scan, the volume of exposed tissues is reduced as well as the scatter, which improves image quality [56]. The recommendation of voxel size in endodontics varies—100 µm or less [56], or 76–300 µm [57]. Only a few studies of the present review reported applied both FOV and voxel size during CBCT [31,32,34,37,38,40,46]. Moreover, studies differ in the reported units of measurement—future directions are required to standardize the CBCT protocol reporting in GE. The use of intraoral scanner reduces the number of steps. However, it is not necessary to achieve good results in guided endodontic planning. A conventional impression and gypsum cast scanning can also be successfully used [29,30,31,32,33]. However, the more steps are taken, the higher amount of errors can occur.
Planning and designing the guided endodontic procedure requires thorough anatomical analysis and careful selection of appropriate instruments, such as burs with suitable diameters and lengths. Not only is space a limitation—consideration of root thickness is also crucial, as it significantly influences instrument choice and access technique. When planning access on mandibular incisors, which have narrower roots compared to maxillary teeth, the use of thinner burs is necessary to prevent structural damage and root fracture, as supported by studies within minimally invasive techniques [58]. In this context, tools such as Munce Discovery Burs (CJM Engineering, Santa Barbara, CA, USA) are highly recommended because they offer high precision and ergonomic design, ensuring better control during drilling and thus reducing the risk of fracture or perforation. These tools are widely endorsed in the literature and used by many researchers in both clinical and experimental studies [59]. When selecting the rotational speed of the instruments, it is essential to control the force applied and prevent excessive heat generation, which can damage periapical tissues and the periodontal ligament. The recommended speed, typically around 10,000 rpm, is supported by scientific evidence indicating that proper parameters enhance both safety and precision in endodontic procedures [15]. Effective cooling during the operation, especially when drilling in calcified canals, is critical to prevent thermal tissue damage and preserve the integrity of adjacent bone and ligament structures [60]. It is also important to highlight that the process of planning and preparation within guided endodontics requires a significant investment of time, although this approach consistently demonstrates a reduction in overall procedure duration—typically from a few to several minutes—which has been confirmed in studies [61,62]. Preparing the template and planning the access usually takes approximately 9.4 min, while performing the actual access can be completed in about 30 s. This not only minimizes tissue damage and reduces patient chair time but also lowers the risk of procedural complications. According to studies by Cvek et al. [63], the total failure rate was 20%, including perforation of the root, fracture of a file, or root canal not found, during root canal treatment on incisors with PCO [63]. During the procedure itself, precise control of drilling speed and cooling, along with the avoidance of excessive pressure and heat build-up, is critical to prevent cavitation, perforations, or damage to soft and hard tissues [1]. The use of advanced technologies such as CAD/CAM systems further enhances accuracy by enabling the production of highly precise, three-dimensional templates, as confirmed by various experimental and clinical studies [64]. Moreover, treating calcified root canals traditionally is highly time-consuming. Guided endodontics allows the procedure to be shortened to approximately 5–15 min, which significantly reduces the risk of complications and improves procedural success rates [15,50]. Finally, an essential part of the process is the assessment of treatment outcomes after the intervention. Regular follow-up examinations and monitoring of healing processes enable early detection of potential complications. Technologies and methodologies employed in guided endodontics also ensure greater consistency and predictability of results [31]. Most studies focus on clinical evaluation, such as the absence of pain, other symptoms, and the stability of radiological findings like complete periapical healing. Radiographically, reductions in lesion size, return to normal periodontal ligament space, and the absence of new pathology are common indicators of successful healing. However, some studies lack detailed descriptions of clinical and radiological outcomes, highlighting the need for standardized reporting protocols. Importantly, while short-term assessments (e.g., 24 h, 1 week) can suggest positive results based on pain relief and absence of symptoms, only long-term follow-up (e.g., beyond six months) provides a reliable evaluation of the durability and stability of the treatment outcome. Currently, there are no standardized guidelines regarding the optimal duration and frequency of follow-up visits in guided endodontics, which limits the comparability of results across studies. More standardized measuring protocols and higher quality studies (such as randomized clinical trials) are needed to compare the results of GE. Standardization of disinfection protocols and obturation techniques in guided endodontics would enhance reproducibility and allow more reliable comparison between studies. Furthermore, detailed description of the complete clinical protocol is essential, including the stages following guided access preparation. After successful localization and negotiation of the newly created root canal, adequate chemical disinfection with irrigants such as sodium hypochlorite and EDTA, proper working length determination, mechanical preparation, and three-dimensional obturation must be clearly reported. In addition, analysis of the cost–benefit ratio of guided endodontics should be included. Although GE requires investment in CBCT imaging, digital planning software, CAD/CAM technology, and template fabrication, the reduction in chair time, decreased risk of iatrogenic errors (such as perforations or missed canals), and increased predictability of treatment may justify these costs, particularly in complex cases with pulp canal obliteration. A comprehensive evaluation comparing financial expenditure, clinical efficiency, and long-term outcomes would provide valuable insight into the practical applicability of this technique in daily practice.
This review has several strengths. First, it provides a comprehensive synthesis of available clinical in vivo studies on guided endodontics in cases of pulp canal obliteration. Second, it focuses not only on the technical aspects of the procedure but also on clinical workflow, CBCT parameters, instrument selection, and treatment outcomes, offering a structured overview of the current evidence. Additionally, the inclusion of detailed tables enhances transparency and facilitates comparison between studies. However, certain limitations must be acknowledged. The included studies were predominantly case reports and case series, with a lack of randomized controlled trials and long-term follow-up data. The heterogeneity in reported CBCT parameters, voxel sizes, planning software, bur dimensions, and outcome assessment criteria limited direct comparison between studies. Furthermore, inconsistent reporting of clinical and radiographic follow-up protocols reduced the ability to perform a standardized evaluation of long-term success. These limitations reflect the current stage of development of guided endodontics and highlight the need for higher-quality, standardized clinical studies.

5. Conclusions

In conclusion, although most studies report favorable outcomes, there is still a lack of precise, standardized timeframes and detailed guidelines for assessing the long-term efficacy of this method. Future efforts should focus on establishing unified protocols for technical parameters—such as CBCT settings, bur selection, rotational speed, software planning standards, and quality control intervals—to standardize procedures and improve comparability between clinical centers.

Author Contributions

M.K.: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, Writing—review and editing, Validation, Visualization. W.P.: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, Writing—review and editing, Validation, Visualization. A.Ż.: Project administration, Writing—review and editing, Resources, Supervision. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

No new data were created or analyzed in this study. Data sharing is not applicable to this article.

Conflicts of Interest

The authors declare no conflicts of interest.

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Figure 1. PRISMA flow chart of the selection process.
Figure 1. PRISMA flow chart of the selection process.
Dentistry 14 00195 g001
Table 1. Digital and clinical workflow of guided endodontics.
Table 1. Digital and clinical workflow of guided endodontics.
1. LabolatoryPhase
CBCT & Digital Registration
Acquire CBCT scan (high resolution, small FOV, DICOM format)
Obtain digital arch registration (via intraoral scanner or impression & scanning) (STL format)
Virtual Planning
Overlay CBCT (DICOM) and arch STL in planning software
Localize visible root canal parts
Position virtual drill to reach root canal
Template Design
Design guide covering adjacent teeth surfaces
Adjust sleeve height and diameter for drill
Export STL of the guide
3D Printing
Process STL in slicer software
Print the guide
2. Clinical Phase
Guide Fit Check
Verify fit and stability
Preparation
Mark access point through guide
Remove enamel with diamond bur
Endodontic Procedure
Insert drill through guide hole
Move drill in depth with pumping movements
Clean drill regularly and irrigate root canal
Use hand file to check negotiation
Continue until the drill reaches sleeve dimension
Root Canal Treatment
Locate canal
Proceed with endodontic treatment
Table 2. Data extraction of the literature on guided endodontics in primary endodontic treatment of anterior teeth [27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53].
Table 2. Data extraction of the literature on guided endodontics in primary endodontic treatment of anterior teeth [27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53].
Author,
Year
TeethDiagnosisProblemCBCTFOVVoxel
Size
ImpressionScannerPlanning SoftwarePrinterBur TypeBur SpecificationBur SpeedTemplate SleeveTemplate MaterialTimeWorking LengthPlanned Length of the Drill PathReached Canal Length
Nabavi et al.
(2025) [52]
21PNPCOPlanmeca ProMAX 3D Classic; Planmeca Oy, Helsinki, FinlandNo dataNo dataNoPrimescan scanner, Dentsply Sirona, GermanyBlue Sky Bio LLC, Glenview, Illinois, USASonic 4K 3D Printer, Phrozen Technology, Hsinchu City, Taiwan#1 Munce Discovery Bur
(CJM Engineering, Santa Barbara, CA, USA)
No dataNo dataNo dataResinNo dataNo dataNo dataNo data
Kasar et al.
(2025) [53]
21No dataPCOPlanmeca ProMAX 3D Classic; Planmeca Oy, Helsinki, FinlandNo dataNo dataNoNo data3Shape Implant Studio (3Shape, Copenhagen, Denmark)Ackuretta DENTIQ-120; Ackuretta Technologies, Taipei, TaiwanSurgical bur
(Mani Inc.; Tochigi, Japan
No dataNo dataNo dataNo dataNo data22 mmNo dataNo data
Kuczmaja et al.
(2025) [27]
22No dataPCO and root fractureCarestream 9300 C, Carestream Dental2016, Atlanta, GA, USANo dataNo dataNoCarestream 360Blue Sky Plan 4 softwarePhrozen Sonic Mini 4K, Taipei, Taiwan#1 Munce Discovery Bur
(CJM Engineering, Santa Barbara, CA, USA)
No dataNo data5 mm L,
1.05 mm D
NextDent SG, Istanbul, TurkeyNo dataNo data18 mmNo data
Fernández-Grisales et al.
(2025) [34]
(a) 11
(b) 31
(c) 13
(d) 11
AAPPCOPlanmeca ProMAX 3D Classic; Planmeca Oy, Helsinki, Finland50 × 40 mm0.075 mmNoMedit i700; Medit, Seoul, KoreaPlanmeca RomexisNo data(a–c) Tivoly drill
(d) DSP drilling system
(a) 0.75 mm D and 21 mm L
(b) 0.75 mm D and 23 mm L
(c) 0.9 mm D and 23 mm L
(d) 0.8 mm D and 25.5 mm L
10,000 rpm(a, b) Metal sleeve: 3.5 mm in external D, 0.75 mm in internal D, 5 mm L
(c) Metal sleeve: 3.5 mm external D, 0.9 mm internal D, 5 mm L
(d) No data
Surgical guide resin; Formlabs, Somerville, MA, USANo dataNo dataNo dataWhere the calclification-free canal could be identified
(c) 14 mm, 19 mm—with template
(d) 17 mm, 22 mm—with template
Abdulwahed et al. (2024) [35]11AAPPCOOrthophos S 3D, Dentsply Sirona, Bensheim, GermanyNo dataNo dataNo3Shape Trios, Copenhagen, DenmarkBlueskyPlan, Libertyville, ILAsiga MAX, Asiga, Alexandria, NSW, AustraliaMunce Discovery Bur
(CJM Engineering, Santa Barbara, CA, USA)
No dataNo dataNo dataNo dataNo dataNo data9 mm (with template 16.01 mm)No data
MahjourianQomi et al.
(2024) [36]
(a) 31
(b) 41
(c) 42
(a) AAP
(b) AAP
(c) PN
PCOPlanmeca ProMAX 3D Classic; Planmeca Oy, Helsinki, FinlandNo dataNo dataNo3Shape Trios, Copenhagen, DenmarkDental System v2017; 3Shape, Copenhagen, DenmarkSonic 4K 3D Printer, Phrozen Technology, Hsinchu City, TaiwanMunce Discovery Bur size #1
(CJM Engineering, Santa Barbara, CA, USA)
No dataNo dataNo dataPhotopolymerized biocompatible polymer resin (PowerResins SG, Singapore)No dataNo data(a, b) Between the middle and apical regions
(c) Between the coronal and middle parts
No data
Fornara et al.
(2024) [37]
33SAPPCOMorita Veraview X800, J.Morita, Tokyo, Japan6 × 7 cm0.16 mm reconstruting to raw data with 0.08 mmNoAadva, IOS 100P, GC, Leuven, BelgiumMimics—Materialise, Leuven, BelgiumSelective Laser Melting My Sint100 Sisma, Piovene Rocchette, Italy210L16 205 008 Komet Dental Gear Brassier GmbH & Co. KG, Lemgo, Germany0.8 mm DNo dataSlevelessGrade 23 medical titaniumNo dataNo dataNo dataNo data
Valverde et al.
(2024) [29]
31SAPPCOGIANO HR, Newton, Imola, ItalyNo dataNo dataAdhesive pastes (President, Coltene, Altstätten, Switzerland)AutoScan-DS-EX Pro, Shining 3D, Hangzhou, ChinaNo dataNo dataEG5 drill (Endoguide drill, SS White, Lakewood, CO, USA)34 mm L
1.5 mm D
20 000 rpmNo dataNo data10 minno dataIn the middle third of the rootIn the middle third of the root
Ambu et al.
(2023) [38]
18 calcified single-rooted teethPNPCOHyperion X 5 (MyRay, Cefla, Imola, Italy)6 × 6 cm upper jaw
6 × 7 cm lower jaw
0.16 mm reconstruting to raw data with 0.08 mmNoAadva, IOS 100P, GC, Leuven, BelgiumRealGuide software (3diemme, Cantů, Italy)SprintRay Pro 95 DLP Technology, SprintRay, Los Angeles, CA, USANo data22 mm L
0.75 mm D lower teeth
0.9 mm D upper teeth
10,000 rpm5 mm L
3.5 mm external D
0.75 mm internal D lower teeth
0.9 mm D upper teeth
No dataNo dataNo dataWhere the calcification-free canal could be detectedTeeth with optimal bur course: After reaching the WL with the bur, the canal was accessed and filled.
Teeth with acceptable bur course: After reaching the bur length, the canal was further widened under the microscope using ultrasonic tips until patency was achieved
Lewis et al.
(2023) [39]
22PN with periapical cystPCOiCAT; Imaging Sciences International, Hatfield, PA, USANo dataNo dataNo3Shape Trios, Copenhagen, Denmark3Shape Implant Suite™3ShapeET bur34 mm L
0.6 mm D
No dataNo dataResinNo dataNo data17 mm15 mm
Zargar et al.
(2023) [40]
21AAPPCONewTom Vgi, Verona, Italy6 × 6 cm0.1 mmNo3Shape Trios, Copenhagen, DenmarkBlueskyPlan, Libertyville, ILDentafab, Istanbul, TurkeyMunce bur size 1 (Meisinger, Germany)16 mm L
0.8 mm D
No dataMetal customized guiding sleeve
5 mm L
3 mm external D
1 mm internal D
ResinNo dataNo data6 mm above the apexNo data
Braga Diniz et al. (2022) [28](a) 12
(b) 11
(c) 12
(1) No data
(2) AAP
(3) Coronary fracture
PCO and previous iatrogenic deviationiCAT; Imaging Sciences International, Hatfield, PA, USANo data0.12 mmNo3Shape Trios, Copenhagen, DenmarkSimPlant Version 15.0 Pro; Materialise Dental, Leuven, BelgiumObjet Eden 260 V, Stratasys Ltd., Mineapolis, MN, USANeodent Drill for TempImplants, Ref.: 103179; JJGC Ind. E Comercio de Materiais Dentarios SA, Curitiba, BrazilNo data1200 rpmNo dataMED 610No dataNo dataNo dataNo data
Nabavi et al.
(2022) [41]
(a) 31
(b) 41
(c) 42
PNPCOPlanmeca ProMAX 3D Classic; Planmeca Oy, Helsinki, FinlandNo dataNo dataNo3Shape Trios, Warren, NJ, USADental System v2017; 3Shape, Copenhagen, DenmarkSonic 4K 3D Printer; Phrozen Technology; TaiwanMunce Discovery Bur size 1
(CJM Engineering, Santa Barbara, CA, USA)
0.7 mm DNo dataNo dataNo dataNo dataNo dataNo dataNo data
Loureiro et al.
(2021) [30]
21AAPPCONo dataNo dataNo dataSilicon Express XT, 3 M, Sumaré, Brazil3Shape Trios, Copenhagen, DenmarkcoDiagnostix (Dental Wings Inc., Montreal, QC, Canada)Moonray DLP 3D-Printer (Sprintray, Los Angeles, CA, USA)(1) Experimental diamond bur Helse Ultrasonic, Ribeirăo Preto, Brazil
(2) Implant drill
(1) 1.5 mm D
(2) 1.3 mm D
(2) 800 rpm1.5 mm D guide tube (Neodent, Curitiba, Brazil)Surgical guide resin (Sprintray, Los Angeles, CA, USA)No dataNo dataIn the apical thirdNo data
Velmurugan et al. (2021) [42](a) 12
(b) 21
(c) 21
(a) SAP
(b) SAP
(c) SAP
PCORomexis software Planmeca, FinlandNo data0.075–0.15 mmNoShining 3D; Hangzhou, ChinaGeomagic Freeform plus; Haptic Technology 3D systems, Rock Hill, USAForm2, Formlabs INC., Somerville, MA, USAGates-Glidden drill no. 20.8 mm DNo dataNo dataTransparent resin15 minNo dataNo data(a) In the middle third region
(b) In the middle third region
(c) No data
Llaquet Pujol et al.
(2021) [43]
(a) 21
(b) 13
(c) 21
(d) 11
(e) 11
(f) 21
(g) 11
(a) SAP
(b) CAA
(c) AAA
(d) SAP
(e) AAA
(f) AAP
(g) AAP
PCONewtom5GXL; Newtom, Verona, ItalyNo dataNo dataNo3Shape Trios, Copenhagen, DenmarkBlueskyPlan, Libertyville, IL, USANo dataCylindrical diamond bur21 mm L
1 mm D
10,000 rpmNo data(a) PMMA
(b) SLA
(c) FDM
(d) FDM
(e) SLA
(e) PMMA
G PMMA
No dataNo dataNo dataNo data
Freire et al.
(2021) [44]
21AAPPCOPrexion 3D Elite; Terarecon, SanMateo, USANo data0.1 mmNo3Shape Trios, Holmens Kanal, Copenhagen, DenmarkImplantViewer, Anne Solutions, Săo Paulo, BrazilForm2, Formlabs INC., Somerville, MA, USADiamond bur Neodent, Ref. 103179; Curitiba, Brazil20 mm L
1.3 mm D
10,000 rpmNo dataNo dataNo data21.5 mmNo dataNo data
Todd et al.
(2021) [45]
22PN, SAPPCODentsply SironaNo dataNo dataNoCerec, Dentsply SironaSicat EndoNo dataNo data24 mm LNo dataMetal (Sicat Endo)No dataNo data21 mm18 mm—from the incisal edge to the observable canal18 mm
Ishak et al.
(2020) [46]
(a) 31
(b) 41
PNPCOVGI evo, NewTom, Verona, Italy24 × 190.2 mmNo3Shape Trios, Copenhagen, Denmark3shape, Copenhagen, DenmarkAsiga Max, Sydeny, AustraliaFFDM, Pneumonat, Bourges, France0.75 mm DNo data5 mm L
1 mm external D
0.85 internal D
No dataNo data(a) 15.5 mm
(b) 15 mm
(a) 9 mm
(b) 4 mm
(a) 12.5 mm
(b) middle third of the root
Silva et al.
(2020) [47]
22PNPCONo dataNo dataNo dataNo3Shape R700Scanner, Holmens Kanal, Copenhagen, DenmarkSimPlant Version 11; Materialise Dental, Leuven, BelgiumNo dataNeodent Drill for TempImplants, refe. 103179, JJGC Ind and Dental Materials Trade SA, Curitiba, Brazil20 mm L
1.3 mmD
10,000 rpmNo dataNo dataNo dataNo dataVisible canal in the apical third of the rootNo data
Hedge et al.
(2020) [48]
11AAPPCOPLANMECANo dataNo dataNoCS3500-KODAK, CarestreamBlueskyPlan, Libertyville, IL, USAFormLabs2Round bur (LN surgical round bur (Mani)28 mm L
010–1mm D?
No dataYesClear resin (FormLabs 2)15 minNo dataNo dataThe junction of the middle and apical third
Buchgreitz et al.
(2018) [49]
(a) 11, 21–17
(b) 12, 22–14
(c) 13, 23–5
(d) 31, 41–9
(e) 32, 42–4
(f) 33, 43-1
PCO with signs of SAP-44
PCO in need of a post–6
PCOOrthophos XG 3D unit, Sirona Dental Systems, Bensheim, GermanyNo data0.5 mmNoCerec, Sirona Dental SystemsGalaxis/Galileos Implant, Sirona Dental SystemsCNC technology Sicat optiguide, Bonn, Germany(1) Highspeed bur–enamel
(2) Modified spiral bur (Busch, Engelskirchen, Germany)-dentine
(2) 1.2 mm D(2) 250 rpmMetal
1.2 mm internal D
CNC technology Sicat optiguide
No dataNo dataNo dataThe drill path was designed to reach the first visible part of the root canalNo data;
better precision when length of the drill path is longer than pulp space obliteration
Torres et al.
(2019) [31]
22AAPPCO,VGI evo, NewTom, Verona, Italy10 × 10 cm0.2 mmAlginateActivity 885, SmartOptics, Bochum, GermanyMimics Medical software 19.0 (Materialise, Leuven, Belgium)
3-matic Medical software 11.0 (Materialise)
Objet Connex 350 3D Printer (Stratasys, Eden Prairie, MN, USA)Munce Discovery Bur size 1
(CJM Engineering, Santa Barbara, CA, USA)
34 mm L
0.8 mm D (head)
10,000 rpm7 mm L
1 mm D
MED 610No dataNo dataNo dataNo data
Thorz et al.
(2019) [32]
31SAPPCOOrthophos SL, Dentsply Sirona, Bensheim, Germany5 × 5 cm0.08 mmAlginateNo dataSicat EndoNo dataSpiral carbide bur (Hager&meisinger, Neuss, Germany)24 mm L
1.2 mm D
5000 rpmMetalNo data10 min to localize pulp spaceNo dataApical third of the rootShallower than virtually planned depth
Lara-Mendes et al.
(2018) [50]
21SAPPCOiCAT; Imaging Sciences International, Hatfield, PANo data0.12 mmNoR700 Desktop Scanner (3Shape, Warren, NJ, USA)SimPlant Version 11; Materialise Dental, Leuven, BelgiumObjet Eden 260 V, Stratsys Ltd., Mineapolis, MN, USA(1) FG 1014 HL (KG Sorensen, Cotia, SP, Brazil)–enamel
(2) Neodent Drill for TempImplants, Ref. 103179; JJGC Ind e Comercio de Materiais Dentarios SA, Curitiba, Brazil
(2) 20 mm total L,
12 mm working L
1.3 mm D
1200 rpmRef. 102110; JJGC Ind e Comercio de Materiais Dentarios SA
8 mm L
3 mm external D
1.4 mm internal D
FullCure 720No dataNo data11.79 mmNo data
FonsecaTavares et al.
(2018) [33]
(a) 11
(b) 11
(a) SAP
(b) SAP
PCONo dataNo dataNo dataSilicon3Shape R700Scanner, Holmens Kanal, Copenhagen, DenmarkSimPlant Version 11; Materialise Dental, Leuven, BelgiumObjet Eden 260 V, Stratsys Ltd., Mineapolis, MN, USANeodent Drill for TempImplants
Ref. 103179; JJGC Ind e Comercio de Materiais Dentarios SA, Curitiba, Brazil
20 mm L
1.3 mm D
10,000 rpmMetalFullCure 720No dataNo data(a) Apical one third of the toothNo data
Connert et al.
(2018) [51]
(a) 31
(b) 41
(a) PN
(b) SAP
PCOAccuitomo 80; J. Morita Mfg. Corp., Irvine, CA, USANo dataNo dataNoiTero, AlignTechnology Inc., San Jose, CA, USA)coDiagnostix (Dental Wings Inc., Montreal, SC, Canada)Objet Eden 260 V, Stratasys Ltd., Mineapolis, MN, USA)Gebr.Brasseler GmbH&Co. KG, Lemgo, Germany)0.85 mm D10,000 rpmSteco–system–technik GmbH & Co. KG, Hamburg, GermanyMED 610No dataNo data4 mm from the apexNo data
Krastl et al.
(2016) [15]
11SAPPCOAccuitomo 80; J. Morita Mfg. Corp., Irvine, CA, USA50 × 500.08 mmNoiTero, AlignTechnology Inc., San Jose, CA, USA)coDiagnostix (Dental Wings Inc., Montreal, SC, Canada)Objet Eden 260 V, Stratsys Ltd., Mineapolis, MN, USAStraumann Drill for TempImplants, Ref.: 80381; Institut Straumann, Basel, Switzerland37 mm total L
18.5 mm working L
1.5 mm D
10,000 rpmMetal fabricated by CNC technology
6 mm L
2.8 mm extarnal D
1.5 mm internal D
MED 6105 min–location of the root canal24.4 mm7.7 mm from the apex9 mm from the apex,
approximately 1 mm from the target point
Letter coding: PCO—pulp canal obliteration; SAP—symptomatic apical periodontits, AAP—asymptomatic apical periodontits, CAA—chronical apical abscess, AAA—acute apical abscess, PN—pulp necrosis. L—length, D—diameter; WL—working length. PMMA—polymethyl methacrylate, SLA—stereolithography resin, #—size1, FDM—fused deposition modeling.
Table 3. The clinical and radiological follow-up.
Table 3. The clinical and radiological follow-up.
Authors, YearFollow-Up: TimeFollow-Up: PainFollow-Up: Healing/Symptoms
Nabavi et al. (2025) [52]18 monthsAsymptomaticThe lesion had completely healed
Kasar et al. (2025) [53]No dataNo dataNo data
Kuczmaja et al. (2025) [27]3 months, 6 months, 1 yearNo painNo signs of discomfort, tenderness, or radiographic abnormalities
Fernández-Grisales et al. (2025) [34](a) 18 months,
(b) 6 months
(c) 18 months
(d) 6 months
No data(b) No data
(a, c, d) Periapical healing achieved
Abdulwahed et al. (2024) [35]1 yearNo dataComplete healing
MahjourianQomi et al. (2024) [36]6 monthsAsymptomaticA normal periodontal ligament space around the apex
Fornara et al. (2024) [37]2 yearsNo painComplete healing
Valverde et al. (2024) [29]3 yearsabsence of clinical symptomsreduction in the size of the periapical reaction
Ambu et al. (2023) [38]One weekNo dataNo data
Lewis et al. (2023) [39]3 monthsAsymptomaticTooth is functional as normal
Zargar et al. (2023) [40]18 monthsAsymptomaticApical lesion was healed
Braga Diniz et al. (2022) [28](a) 1 year
(b) 1 year
(c) 15 days
AsymptomaticNo data
Nabavi et al. (2022) [41]6 monthsAsymptomaticNormal function
Loureiro et al. (2021) [30]6 monthsNo symptomsNo signs of periapical pathology
Velmurugan et al. (2021) [42](a) 18 months
(b) 1 year
(c) 1 year
(a) Asymptomatic
(b) Asymptomatic
(c) Asymptomatic
No data
Llaquet Pujol et al. (2021) [43]1 yearNo painPeriapical healing achieved
Freire et al. (2021) [44](a) 60 days
(b) 2 years
(a) Discreet pain
(b) Asymptomatic
(b) Asymptomatic healing
Todd et al. (2021) [45]24 hShe was comfortableNo data
Ishak et al. (2020) [46]No dataNo dataNo data
Silva et al. (2020) [47]1 yearNo dataIntegrity of treatment
Hedge et al. (2020) [48]No dataNo dataNo data
Buchgreitz et al. (2018) [49]No dataNo dataNo data
Torres et al. (2019) [31]6 monthsThe absence of symptomsCompletly healed periapical area
Thorz et al. (2019) [32]No dataNo dataNo data
Lara-Mendes et al. (2018) [50]1 yearAsymptomaticSmall alteration in the periodontal ligament space which may be a sign of scar tissue
FonsecaTavares et al. (2018) [33](a) 15 days
(b) 30 days
AsymptomaticNo data
Connert et al. (2018) [51]No dataNo dataNo data
Krastl et al. (2016) [15]15 monthsNo painNo signs of apical pathology
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Kuczmaja, M.; Puchalska, W.; Żółtowska, A. Static Guided Endodontics in Primary Endodontic Treatment of Anterior Teeth: A Narrative Review. Dent. J. 2026, 14, 195. https://doi.org/10.3390/dj14040195

AMA Style

Kuczmaja M, Puchalska W, Żółtowska A. Static Guided Endodontics in Primary Endodontic Treatment of Anterior Teeth: A Narrative Review. Dentistry Journal. 2026; 14(4):195. https://doi.org/10.3390/dj14040195

Chicago/Turabian Style

Kuczmaja, Monika, Wiesława Puchalska, and Agata Żółtowska. 2026. "Static Guided Endodontics in Primary Endodontic Treatment of Anterior Teeth: A Narrative Review" Dentistry Journal 14, no. 4: 195. https://doi.org/10.3390/dj14040195

APA Style

Kuczmaja, M., Puchalska, W., & Żółtowska, A. (2026). Static Guided Endodontics in Primary Endodontic Treatment of Anterior Teeth: A Narrative Review. Dentistry Journal, 14(4), 195. https://doi.org/10.3390/dj14040195

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