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Open AccessReview

Smart MRI Agents for Detecting Extracellular Events In Vivo: Progress and Challenges

1
Department of Radiology, UT Southwestern Medical Center, Dallas, TX 75390, USA
2
Department of Chemistry, University of Texas at Dallas, Dallas, TX 75080, USA
3
Werner Siemens Imaging Center, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany
*
Author to whom correspondence should be addressed.
Inorganics 2019, 7(2), 18; https://doi.org/10.3390/inorganics7020018
Received: 3 January 2019 / Revised: 25 January 2019 / Accepted: 29 January 2019 / Published: 9 February 2019
(This article belongs to the Special Issue MRI Contrast Agents)
Many elegant inorganic designs have been developed to aid medical imaging. We know better now how to improve imaging due to the enormous efforts made by scientists in probe design and other fundamental sciences, including inorganic chemistry, physiochemistry, analytical chemistry, and biomedical engineering. However, despite several years being invested in the development of diagnostic probes, only a few examples have shown applicability in MRI in vivo. In this short review, we aim to show the reader the latest advances in the application of inorganic agents in preclinical MRI. View Full-Text
Keywords: MRI; contrast agents; paramagnetic agents; responsive sensors; smart sensors MRI; contrast agents; paramagnetic agents; responsive sensors; smart sensors
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MDPI and ACS Style

Parrott, D.; Fernando, W.S.; Martins, A.F. Smart MRI Agents for Detecting Extracellular Events In Vivo: Progress and Challenges. Inorganics 2019, 7, 18.

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